The authors declare that they have no competing interests.
UK : Conception and overall experimental management, head of Department of Plastic, Reconstructive Microsurgery. HD : Neck surgery, analysis and interpretation of data. AD : Neck surgery, acquisition of data. SJ : Surgical anesthesia, acquisition of data. AT : Drafting the manuscript. MM : Experimental design and manuscript drafting and revision, Co-head of Regenerative Medicine. All authors read and approved the final manuscript.
Management of asthma in chronically affected patients is a serious health problem. Our aim was to show that surgical treatment of chronic bronchial asthma by unilateral resection of the internal branch of the superior laryngeal nerve (ib-SLN) is an adequateand lasting remedial response.
In a retrospective study, 41 (26 male and 15 female) patients with bronchial chronic asthma were treated surgically during the period between 2005 and 2013. It consisted of a unilateral resection of the ib-SLN under optical zoom, on patients placed in supinator position. 35 patients (24 male and 11 female) who were un-operated were included as a control.
In all patients, medication was reduced progressively. When the results were compared with the control group, it was seen that in 26 % of the patients, both forced expiratory volume (FEV) and peak expiratory flow (PEF) increased significantly (p <05) and only modestly in 53.6 % of patients (FEV, p <05 and PEF, p <05). In the remaining 20 % of patients, these parameters remained however unchanged. Overall, in 80 % of patients unilateral resection of the ib-SLN gave satisfactory results because it shortened the intervals and duration of asthmatic attacks, rendering thereby a reduction in medication.
This minimal-invasive method helped prevent/cure asphyxias in chronic bronchial asthma without affecting cough reflex,respiratory control and phonation and it helped patients avoid severe crisis. This approach is of interest for patients with severe and/or uncontrolled bronchial asthma in settings with limited access to drug treatment.
Smakov GМ. Complications under surgical treatment of patients with bronchial asthma. Surgery. 1990;2:124–7.
Babichev SI, Smakov GM, Savchenko ZI, Shestov A. Status of the regulatory systems and substantiation of the indicators for conservative and surgical treatments of patients with bronchial asthma. Klin Med (Mosk). 1990;68(8):64–8.
Savchenko ZI, Shestov A. Evaluation of neurohumoral reactions in the selection of surgical methods for patients with bronchial asthma. Khirurgiia (Mosk). 1990;11:88–91.
Savchenko ZI, Smakov GM. Adaptation of regulatory physiological systems in surgical treatment of patients with bronchial asthma]. Klin Med (Mosk). 1996;74(7):38–9.
Engelmann C. Do surgical interventions in bronchial asthma promise success? Z ArztlFortbild (Jena). 1989;83(12):605–8.
Nolte D. Asthma operations: new wine in old pitchers? Med Klin (Munich). 1986;81(8):297–8.
Feofilov GL, Меlnikov VМ. New approach in surgical treatment of bronchial asthma. Toracal Cardiovasc Surg. 1996;2:54–7.
Feofilov GL, Mel′nikov VM, Bushuev AA, Osipov VP, Levitskiĭ VA, Vitsyn AE. [First experience in the treatment of bronchial asthma by resection of the superior laryngeal nerve]. Grud Serdechnososudistaia Khir. 1992;(1-2):45–7.
Gudoski LM, Karashurov SE, Karashurov ES, Volkov AA, Parshin VD. [Surgical treatment of bronchial asthma].Khirurgiia (Mosk) 2002;(7):14–18.
Ulmer WT, Zimmermann I, Schlenkhoff D. Einseitigevagus-sympathikus durchtrennungdes (KUX-Operation) Undeinseige Durchtrennung desnervus laryngeus craniallis (Bochumer Operation) beipatient enumitchronischer Atemwegs obstruktion Referat: Bochumer Treff, mai 1981. Munchen: Gedon-ReubVerlag; 1981.
Stedman HM, Bradley RM, Mistretta CM, Bradley BE. Chemosensitive responses from the cat epiglottis. Chem Senses. 1980;5:233–45. CrossRef
Melnikov VM, Volkov AV, Kapustin DV. Remote results of surgical treatment of bronchial asthma, indications and selecting the method of operation. Questions of Reconstr and Plastic Surg. 2014;1:94–8.
Zong Q, Zhang K, Han G, Yang S, Wang L, Li H. Rhizotomy targeting the intermediate nerve, the glossopharyngeal nerve and the upper 1st to 2nd rootlets of the vagus nerve for the treatment of laryngeal neuralgia combined with intermediate nerve neuralgia-a case report. BMC Surg. 2014;14:60. doi: 10.1186/1471-2482-14-60. PubMedCentralCrossRefPubMed
- Surgical treatment of bronchial asthma by resection of the laryngeal nerve
- BioMed Central
Neu im Fachgebiet Chirurgie
Mail Icon II