Erschienen in:
22.01.2019 | Case Report
Surgically resected pancreatic metastasis from nasal malignant melanoma: case report and literature review
verfasst von:
Yoshihide Kanno, Yutaka Noda, Shinsuke Koshita, Takahisa Ogawa, Kaori Masu, Masaya Oikawa, Takaho Okada, Naoya Akazawa, Takashi Sawai, Kei Ito
Erschienen in:
Clinical Journal of Gastroenterology
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Ausgabe 4/2019
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Abstract
A 13-mm mass was observed in the pancreatic head of a 70-year-old woman who had undergone melanoma resection in the nasal cavity 10 years earlier. Endoscopic ultrasonography (EUS) showed that the mass consisted of multiple hypoechoic nodules. EUS-guided fine needle aspiration and pancreatic juice cytologies revealed neoplastic cells positive for HMB45 and melan-A staining with a few melanin granules, indicating the presence of a metastatic malignant melanoma. These additional stainings were evaluated after surgery. In the surgically resected specimen, the mass had multiple nodule-like structures, some of which were brown colored. Immunocytochemistry and electronic microscopy findings confirmed the diagnosis of malignant melanoma. Microscopic findings were similar to the nasal specimen; therefore, the pancreatic lesion was considered to be a metastasis from the nasal cavity.