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18.06.2021 | Research Communication

Survival Outcomes for Colorectal Cancer with Isolated Liver Metastases at Academic Versus Community Hospitals

verfasst von: Vanessa M. Welten, Adam C. Fields, James Yoo, Jennifer L. Irani, Joel E. Goldberg, Ronald Bleday, Nelya Melnitchouk

Erschienen in: Journal of Gastrointestinal Surgery | Ausgabe 1/2022

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Excerpt

Colorectal cancer is the third leading cause of cancer-related deaths in the USA. Twenty to twenty-five percent of patients with colorectal cancer present with metastatic disease at diagnosis, with liver being the most common site of distant metastasis. ^1‐3 Survival has greatly improved over time with the introduction of metastasectomy, with 5-year survival rates ranging from 38 to as high as 58%. ^4‐6 Hepatic resection is now the treatment of choice for isolated resectable colorectal liver metastases. ⁵ We aim to compare outcomes for patients with stage IV colon and rectal cancer with isolated liver metastases treated at academic versus community hospitals. …

Robinson JR, Newcomb PA, Hardikar S, Cohen SA, Phipps AI. Stage IV colorectal cancer primary site and patterns of distant metastasis. Cancer Epidemiol. 2017;48:92-5. doi: https://doi.org/10.1016/j.canep.2017.04.003. CrossRefPubMedPubMedCentral

van der Geest LG, Lam-Boer J, Koopman M, Verhoef C, Elferink MA, de Wilt JH. Nationwide trends in incidence, treatment and survival of colorectal cancer patients with synchronous metastases. Clin Exp Metastasis. 2015;32(5):457-65. doi: https://doi.org/10.1007/s10585-015-9719-0. CrossRefPubMed

Stewart CL, Warner S, Ito K, Raoof M, Wu GX, Kessler J et al. Cytoreduction for colorectal metastases: liver, lung, peritoneum, lymph nodes, bone, brain. When does it palliate, prolong survival, and potentially cure? Curr Probl Surg. 2018;55(9):330-79. doi: https://doi.org/10.1067/j.cpsurg.2018.08.004. CrossRefPubMedPubMedCentral

Abdalla EK, Vauthey JN, Ellis LM, Ellis V, Pollock R, Broglio KR et al. Recurrence and outcomes following hepatic resection, radiofrequency ablation, and combined resection/ablation for colorectal liver metastases. Ann Surg. 2004;239(6):818-25; discussion 25-7. https://doi.org/10.1097/01.sla.0000128305.90650.71. CrossRefPubMedPubMedCentral

NCCN. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines): Colon Cancer2021 January 21 2021.

Stelzner S, Radulova-Mauersberger O, Zschuppe E, Kittner T, Abolmaali N, Puffer E et al. Prognosis in patients with synchronous colorectal cancer metastases after complete resection of the primary tumor and the metastases. J Surg Oncol. 2019;120(3):438-45. doi: https://doi.org/10.1002/jso.25578. CrossRefPubMed

Titel: Survival Outcomes for Colorectal Cancer with Isolated Liver Metastases at Academic Versus Community Hospitals
verfasst von: Vanessa M. Welten
Adam C. Fields
James Yoo
Jennifer L. Irani
Joel E. Goldberg
Ronald Bleday
Nelya Melnitchouk
Publikationsdatum: 18.06.2021
Verlag: Springer US
Erschienen in: Journal of Gastrointestinal Surgery / Ausgabe 1/2022
Print ISSN: 1091-255X
Elektronische ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-021-05062-6

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Survival Outcomes for Colorectal Cancer with Isolated Liver Metastases at Academic Versus Community Hospitals

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