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Erschienen in: Rheumatology International 10/2012

01.10.2012 | Case Report

Systemic sclerosis sine scleroderma associated with antiphospholipid syndrome

verfasst von: Pollyanna d’Ávila Leite, Jozélio Freire de Carvalho

Erschienen in: Rheumatology International | Ausgabe 10/2012

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Abstract

The antiphospholipid syndrome (APS) can be primary, when it occurs alone, or secondary, when it is associated with another autoimmune disease, mainly systemic lupus erythematosus and rarely other autoimmune diseases. Cases described in literature (Medline 1966 to December 2009) associate the presence of antiphospholipid antibodies with the presence of APS and systemic sclerosis (SS). Currently, however, no cases of the SS variant sine scleroderma with APS have been described. In this study, the authors describe the case of a patient with APS characterised by thrombosis of the retinal veins, in May 2006, the presence of lupus anticoagulant and an anticardiolipin IgG antibody. In May 2007, this patient developed Raynaud’s phenomenon, a lack of oesophageal motility and nailfold capillaroscopy with a scleroderma pattern. The patient was positive for the anti-centromere antibody but lacked any evidence of cutaneous thickening or involvement. In summary, the authors describe the first case of a patient with APS associated with SS sine scleroderma.
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Metadaten
Titel
Systemic sclerosis sine scleroderma associated with antiphospholipid syndrome
verfasst von
Pollyanna d’Ávila Leite
Jozélio Freire de Carvalho
Publikationsdatum
01.10.2012
Verlag
Springer-Verlag
Erschienen in
Rheumatology International / Ausgabe 10/2012
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-010-1482-6

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