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Targeted Oncology

Ausgabe 3/2016

Inhalt (15 Artikel)

Review Article

Targeted Therapies for the Treatment of Brain Metastases in Solid Tumors

Jan-Paul Bohn, Georg Pall, Guenther Stockhammer, Michael Steurer

Review Article

Systematic Review of the Side Effects Associated With Anti-HER2-Targeted Therapies Used in the Treatment of Breast Cancer, on Behalf of the EORTC Quality of Life Group

Samantha C. Sodergren, Ellen Copson, Alice White, Fabio Efficace, Mirjam Sprangers, Deborah Fitzsimmons, Andrew Bottomley, Colin D. Johnson

Open Access Review Article

A Review of Clinical Studies and Practical Guide for the Administration of Triplet Chemotherapy Regimens with Bevacizumab in First-line Metastatic Colorectal Cancer

Fotios Loupakis, Alexander Stein, Marc Ychou, Frank Hermann, Antonieta Salud, Pia Österlund

Original Research Article

Phase 1 Study of Monotherapy with KHK2866, an Anti-Heparin-Binding Epidermal Growth Factor-Like Growth Factor Monoclonal Antibody, in Patients with Advanced Cancer

John Sarantopoulos, Monica M. Mita, Michael J. Birrer, Lee D. Cranmer, Luis T. Campos, Xiaoping Zhang, Penelope Bristow, Hidekuni Kaito, Vincent Strout, Luis H. Camacho

Original Research Article

Changes in Renal Function of Patients with Metastatic Renal Cell Carcinoma During Treatment with Molecular-Targeted Agents

Hideaki Miyake, Mototsugu Muramaki, Satoshi Imai, Ken-ichi Harada, Masato Fujisawa

Original Research Article

Dose-Dense Temozolomide in Patients with MGMT-Silenced Chemorefractory Colorectal Cancer

Filippo Pietrantonio, Filippo de Braud, Massimo Milione, Claudia Maggi, Roberto Iacovelli, Katia Fiorella Dotti, Federica Perrone, Elena Tamborini, Marta Caporale, Rosa Berenato, Giorgia Leone, Alessio Pellegrinelli, Ilaria Bossi, Fabrizio Festinese, Stefano Federici, Maria Di Bartolomeo

Original Research Article

Magnitude of PD-1, PD-L1 and T Lymphocyte Expression on Tissue from Castration-Resistant Prostate Adenocarcinoma: An Exploratory Analysis

Francesco Massari, Chiara Ciccarese, Anna Caliò, Enrico Munari, Luca Cima, Antonio Benito Porcaro, Giovanni Novella, Walter Artibani, Teodoro Sava, Albino Eccher, Claudio Ghimenton, Francesco Bertoldo, Aldo Scarpa, Nicola Sperandio, Camillo Porta, Vincenzo Bronte, Marco Chilosi, Giuseppe Bogina, Giuseppe Zamboni, Giampaolo Tortora, Hemamali Samaratunga, Guido Martignoni, Matteo Brunelli

Original Research Article

Heterodimeric Bispecific Single Chain Variable Fragments (scFv) Killer Engagers (BiKEs) Enhance NK-cell Activity Against CD133+ Colorectal Cancer Cells

J. U. Schmohl, M. K. Gleason, P. R. Dougherty, J. S. Miller, D. A. Vallera

Original Research Article

Rare RAS Mutations in Metastatic Colorectal Cancer Detected During Routine RAS Genotyping Using Next Generation Sequencing

Alexandre Harlé, Pierre Filhine-Tresarrieu, Marie Husson, Romain Boidot, Marie Rouyer, Cindy Dubois, Agnès Leroux, Jean-Louis Merlin

Original Research Article

Afatinib, an Irreversible EGFR Family Inhibitor, Shows Activity Toward Pancreatic Cancer Cells, Alone and in Combination with Radiotherapy, Independent of KRAS Status

Florence Huguet, Marie Fernet, Nicole Giocanti, Vincent Favaudon, Annette K. Larsen

Original Research Article

Aflibercept Plus FOLFIRI vs. Placebo Plus FOLFIRI in Second-Line Metastatic Colorectal Cancer: a Post Hoc Analysis of Survival from the Phase III VELOUR Study Subsequent to Exclusion of Patients who had Recurrence During or Within 6 Months of Completing Adjuvant Oxaliplatin-Based Therapy

Eric Van Cutsem, Florence Joulain, Paulo M. Hoff, Edith Mitchell, Paul Ruff, Radek Lakomý, Jana Prausová, Vladimir M. Moiseyenko, Guy van Hazel, David Cunningham, Dirk Arnold, Hans-Joachim Schmoll, Albert J. ten Tije, Joseph McKendrick, Hendrik Kröning, Yves Humblet, Cristina Grávalos, Solenn Le-Guennec, Michael Andria, Emmanuelle Dochy, Raghu L. Vishwanath, Teresa Macarulla, Josep Tabernero

Original Research Article

An Adaptive Study to Determine the Optimal Dose of the Tablet Formulation of the PARP Inhibitor Olaparib

J. Mateo, V. Moreno, A. Gupta, S. B. Kaye, E. Dean, M. R. Middleton, M. Friedlander, C. Gourley, R. Plummer, G. Rustin, C. Sessa, K. Leunen, J. Ledermann, H. Swaisland, A. Fielding, W. Bannister, S. Nicum, L. R. Molife

Erratum

Erratum to: Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized Phase III Trial of Erlotinib Versus Observation in Ovarian Cancer Patients with No Evidence of Disease Progression after First-Line Platinum-Based Chemotherapy

Evelyn Despierre, Ignace Vergote, Ryan Anderson, Corneel Coens, Dionyssios Katsaros, Fred R. Hirsch, Bram Boeckx, Marileila Varella-Garcia, Annamaria Ferrero, Isabelle Ray-Coquard, John A. Green, Christopher Steer, Els M. J. J. Berns, Antonio Casado, Diether Lambrechts, Antonio Jimeno

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