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Pediatric Cardiology

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01.08.2019 | Riley Symposium

Tbx3-Mediated Regulation of Cardiac Conduction System Development and Function: Potential Contributions of Alternative RNA Processing

verfasst von: Brian P. Delisle, Yao Yu, Pavan Puvvula, Allison R. Hall, Chad Huff, Anne M. Moon

Erschienen in: Pediatric Cardiology | Ausgabe 7/2019

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Abstract

In this article, we provide a brief summary of work by us and others to discover the molecular underpinnings of early conduction system development and function. We focus on how the multifunctional protein Tbx3 contributes to acquisition and homeostasis of the tissue-specific properties of the sinoatrial and atrioventricular nodes. We also provide unpublished, preliminary findings supporting the role of Tbx3-regulated alternative RNA processing in the developing conduction system.

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Titel: Tbx3-Mediated Regulation of Cardiac Conduction System Development and Function: Potential Contributions of Alternative RNA Processing
verfasst von: Brian P. Delisle
Yao Yu
Pavan Puvvula
Allison R. Hall
Chad Huff
Anne M. Moon
Publikationsdatum: 01.08.2019
Verlag: Springer US
Erschienen in: Pediatric Cardiology / Ausgabe 7/2019
Print ISSN: 0172-0643
Elektronische ISSN: 1432-1971
DOI: https://doi.org/10.1007/s00246-019-02166-4

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Tbx3-Mediated Regulation of Cardiac Conduction System Development and Function: Potential Contributions of Alternative RNA Processing

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