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Erschienen in: Brain Structure and Function 6/2021

20.05.2021 | Original Article

The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population

verfasst von: Anna Miró-Padilla, Jesús Adrián-Ventura, Víctor Costumero, María-Ángeles Palomar-García, Esteban Villar-Rodríguez, Lidón Marin-Marin, Naiara Aguirre, Elisenda Bueichekú

Erschienen in: Brain Structure and Function | Ausgabe 6/2021

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Abstract

The adhesio interthalamica (AI) is a small midline brain structure that connects the left and right thalamus. According to in vivo data, between 2.3 and 22.3% of the general population lack the AI, and the question of whether this absence is more prevalent in males than in females is a matter of debate. Despite the existence of these demographic figures, it remains unclear how this distinctive feature affects healthy people, or what specific anatomic profile is related to the presence or absence of the AI. The aim of this study was to investigate whole-brain gray matter (GM) volumetric differences depending on the presence or absence of the AI. A total of 240 healthy adult volunteers completed one MRI scanning session. After the AI assessment, the data from 110 participants were included in the final sample, of which 12.9% of the participants (n = 31) presented complete AI absence vs. 32.9% of participants (n = 79) who presented complete AI presence. Then, whole-brain group comparison analysis revealed that the absent AI brain, compared to the present AI brain, was associated with lower GM volume in the premotor cortex, inferior frontal gyrus, and anterior temporal cortex. Interestingly, neuroscience research has linked emotional and cognitive control brain processing to the latter two regions. The importance of these findings lies in providing a neuroanatomical profile for the absent AI brain in healthy human adults.
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Literatur
Zurück zum Zitat Carter CS, Barch DM, Buchanan RW, Bullmore E, Krystal JH, Cohen J, Geyer M, Green M, Nuechterlein KH, Robbins T, Silverstein S, Smith EE, Strauss M, Wykes T, Heinssen R (2008) Identifying cognitive mechanisms targeted for treatment development in schizophrenia: an overview of the first meeting of the cognitive neuroscience treatment research to improve cognition in schizophrenia initiative. Biol Psychiat 64(1):4–10. https://​doi.​org/​10.​1016/​j.​biopsych.​2008.​03.​020 CrossRefPubMed Carter CS, Barch DM, Buchanan RW, Bullmore E, Krystal JH, Cohen J, Geyer M, Green M, Nuechterlein KH, Robbins T, Silverstein S, Smith EE, Strauss M, Wykes T, Heinssen R (2008) Identifying cognitive mechanisms targeted for treatment development in schizophrenia: an overview of the first meeting of the cognitive neuroscience treatment research to improve cognition in schizophrenia initiative. Biol Psychiat 64(1):4–10. https://​doi.​org/​10.​1016/​j.​biopsych.​2008.​03.​020 CrossRefPubMed
Metadaten
Titel
The adhesio interthalamica as a neuroanatomical marker of structural differences in healthy adult population
verfasst von
Anna Miró-Padilla
Jesús Adrián-Ventura
Víctor Costumero
María-Ángeles Palomar-García
Esteban Villar-Rodríguez
Lidón Marin-Marin
Naiara Aguirre
Elisenda Bueichekú
Publikationsdatum
20.05.2021
Verlag
Springer Berlin Heidelberg
Erschienen in
Brain Structure and Function / Ausgabe 6/2021
Print ISSN: 1863-2653
Elektronische ISSN: 1863-2661
DOI
https://doi.org/10.1007/s00429-021-02297-6

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