Background
Methods
Participants
Assessment of DSM-IV diagnoses, delusional-like experiences and physical disorders
Item G1 (PS1*):
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Have you ever felt that your thoughts were being directly interfered with or controlled by another person? |
If yes, PS1A
#
:
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Did it come about in a way that many people would find hard to believe, for instance, through telepathy? |
Item G2 (PS2*):
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Have you ever had a feeling that people were too interested in you? |
If yes, PS2A
#
:
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Have you had a feeling that things were arranged so as to have a special meaning for you, or even that harm might come to you? |
Item G1 (PS3*):
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Do you ever have any special powers that most people lack? |
If yes, PS3A
#
:
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Do you belong to a group of people who also have these powers? |
Item PS4@: Has a doctor ever told you that you may have schizophrenia? |
Assessment of tobacco, cannabis and alcohol exposure
Data analysis
Results
Exposure | Sample Number (%) | Delusional-like experiences endorsement | |
---|---|---|---|
No (%) | Yes (%)@
| ||
Total sample | 8773 (100.00) | 7997(91.53) | 776 (8.47) |
Everyday tobacco use | 1539 (17.97) | 1325 (15.64) | 214 (13.01) |
Weekly tobacco use | 302 (4.04) | 266 (3.56) | 36 (14.72) |
No tobacco use | 6932 (77.98) | 6406 (72.33) | 526 (7.24) |
Cannabis use disorder, Lifetime | 339 (4.22) | 287 (3.63) | 52 (13.98) |
No Cannabis use disorder | 8434 (95.78) | 7710 (87.89) | 724 (8.23) |
Cannabis dependence disorder, Lifetime | 130 (1.74) | 99 (1.31) | 31 (24.65) |
No Cannabis dependence disorder | 8643 (98.26) | 7898 (90.21) | 745 (8.19) |
Alcohol use disorder, Lifetime | 1490 (18.31) | 1333 (16.60) | 157 (9.35) |
No alcohol use disorder | 7283 (81.69) | 6664 (74.93) | 619 (8.28) |
Alcohol dependence disorder, Lifetime | 329 (3.71) | 249 (2.84) | 80 (23.42) |
No alcohol dependence disorder | 8444 (96.29) | 7748 (88.69) | 249 (7.89) |
Association between tobacco use and DLE
Any Delusional-like experiences | |||||
---|---|---|---|---|---|
Screen items | Probe items | ||||
A. Tobacco use | |||||
Count (%) | Model 11
OR4 (95% CI5) | Model 22
OR4 (95% CI5) | Model 11
OR4 (95% CI5) | Model 22
OR4 (95% CI5) | |
Smoking
| |||||
Everyday | 1539 (17.97) |
1.86 (1.43, 2.43)*
|
1.39 (1.07, 1.81)*
|
2.37 (1.65, 3.39)*
|
1.66 (1.13, 2.44)*
|
Weekly | 302 (4.05) | 1.73 (0.99, 3.02) | 1.28 (0.67, 2.45) |
2.98 (1.09, 8.19)*
| 2.12 (0.65, 6.91) |
Never | 6932 (77.98) |
Reference
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Reference
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Reference
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Reference
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B. Age of start of smoking everyday
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Very early start (Q1: 6-15 y) | 517 (5.78) |
2.26 (1.63, 3.13)
|
1.61 (1.09, 2.36)
|
2.84 (1.82, 4.45)
|
1.82 (1.11, 3.00)
|
Early start (Q2:16-17y) | 352 (4.51) |
1.77 (1.18, 2.66)
| 1.42 (0.92, 2.18) |
2.45 (1.31, 4.59)
| 1.78 (0.89, 3.52) |
Mid age start (Q3: 18-19y) | 307 (3.56) | 1.00 (0.59, 1.69) | 0.79 (0.47, 1.36) | 1.51 (0.69, 3.29) | 1.19 (0.55, 2.61) |
Late start (Q4: 20y+) | 360 (4.10) |
1.93 (1.19, 3.12)
| 1.56 (0.97, 2.51) | 1.56 (0.83, 2.94) | 1.13 (0.61, 2.12) |
Not smoking at all | 7234 (82.04) |
Reference
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Reference
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Reference
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Reference
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C. Number of cigarettes or tobacco products per day
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Very heavy smoker (Q1: 23-75) | 325 (3.97) |
2.19 (1.46, 3.28)
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1.63 (1.06, 2.51)
|
2.35 (1.24, 4.44)
| 1.54 (0.77, 3.09) |
Heavy smoker (Q2:16-22) | 313 (3.24) |
1.76 (1.07, 2.91)
| 1.25 (0.76, 2.07) |
2.71 (1.60, 4.59)
|
1.77 (1.05, 2.99)
|
Light smoker (Q3: 11-15) | 314 (3.80) |
1.65 (1.03, 2.67)
| 1.33 (0.82, 2.15) | 1.72 (0.74, 4.01) | 1.25 (0.52, 3.03) |
Very light smoker (Q4: < 10) | 584 (6.94) |
1.68 (1.13, 2.51)
| 1.32 (0.85, 2.05) |
2.06 (1.24, 3.41)
| 1.52 (0.89, 2.57) |
Not smoking at all | 7234 (82.04) |
Reference
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Reference
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Reference
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Reference
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Association between cannabis use disorders and DLE
Any Delusional-like experiences | |||||
---|---|---|---|---|---|
Screen items | Probe items | ||||
A. Lifetime cannabis use/dependence disorder | |||||
Count (%) | Model 11
OR4 (95% CI5) | Model 22
OR4 (95% CI5) | Model 11
OR4 (95% CI5) | Model 22
OR4 (95% CI5) | |
Cannabis use disorder Cannabis dependence disorder
| 339 (4.23) 130 (1.74) |
1.73 (1.12, 2.66)*
3.53 (1.87, 6.66)*
| 1.13 (0.71, 1.82)
1.76 (1.00, 2.75)*
|
2.28 (1.27, 4.12)*
5.51 (2.75, 11.05)*
| 1.35 (0.73, 2.49)
2.39 (1.14, 4.99)*
|
B. Age of onset of cannabis use disorder
| |||||
Very early onset (Q1: 12-16y) | 131 (1.59) |
3.15 (1.80, 5.49)
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1.85 (1.00, 3.44)
|
5.51 (2.42, 12.58)
|
2.85 (1.18, 6.89)
|
Early onset (Q2:17-18y) | 123 (1.79) | 1.39 (0.69, 2.81) | 1.03 (0.49, 2.15) |
3.08 (1.22, 7.77)
| 2.17 (0.84, 5.59) |
Middle onset (Q3: 19-20y) | 89 (1.26) | 1.77 (0.64, 4.95) | 1.08 (0.41, 2.84) | 1.24 (0.20, 7.66) | 0.70 (0.11, 4.46) |
Late onset (Q4: 21-50y) | 101 (1.09) |
3.38 (1.65, 6.94)
| 1.93 (0.92, 4.05) |
3.47 (1.46, 8.24)
| 1.73 (0.62, 4.82) |
No onset of use disorder | 8329 (94.28) |
Reference
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Reference
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Reference
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Reference
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C. Age of onset of cannabis dependence
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Very early onset (Q1: 12-16y) | 32 (0.38) |
5.83 (2.09, 16.19)
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4.38 (1.39, 13.79)
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12.73 (3.73, 43.66)
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9.41 (2.42, 36.49)
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Early onset (Q2:17-19y) | 37 (0.65) | 1.18 (0.27, 5.09) | 0.76 (0.16, 3.52) | 1.86 (0.49, 7.00) | 1.11 (0.28, 4.44) |
Middle onset (Q3: 20-22y) | 28 (0.28) | 1.43 (0.37, 5.52) | 0.67 (0.16, 2.81) |
-
| - |
Late onset (Q4: 23-50y) | 31 (0.41) |
10.39 (354, 30.56)
|
4.97 (1.58, 15.64)
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6.34 (2.28, 17.63)
| 2.41 (0.76, 7.63) |
No onset | 8645 (98.27) |
Reference
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Reference
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Reference
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Reference
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Association between alcohol use disorders and DLE
Any Delusional-like experiences | |||||
---|---|---|---|---|---|
Screen items | Probe items | ||||
A. Lifetime alcohol use/dependence disorder | |||||
Count (%) | Model 11
OR4 (95% CI5) | Model 22
OR4 (95% CI5) | Model 11
OR4 (95% CI5) | Model 22
OR4 (95% CI5) | |
Alcohol use disorder, lifetime
Alcohol dependence disorder, lifetime
| 1490 (18.31) 329 (3.71, 0.28) | 1.18 (0.89, 1.56)
3.50 (2.33, 5.28)*
| 1.01 (0.76, 1.33)
1.85 (1.15, 2.97)*
| 1.41 (0.97, 2.03)
4.48 (2.39, 8.40)*
| 1.09 (0.72, 1.63) 1.93 (0.91, 4.07) |
B. Age of onset of alcohol use disorder
| |||||
Very early onset (Q1: 9-17y) | 361 (4.49) |
2.26 (1.48, 3.46)
| 1.54 (0.99, 2.39) |
3.50 (1.79, 6.84)
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2.06 (1.02, 4.18)
|
Early onset (Q2:18-19y) | 487 (6.34) | 1.03 (0.70, 1.50) | 0.87 (0.59, 1.29) | 1.40 (0.75, 2.61) | 1.14 (0.59, 2.16) |
Middle onset (Q3: 20-25y) | 509 (6.34) |
1.55 (1.09, 2.19)
| 1.19 (0.80, 1.78) |
2.17 (1.35, 3.51)
| 1.53 (0.87, 2.67) |
Late onset (Q4: 26-79y) | 441 (4.58) |
2.25 (1.45, 3.49)
| 1.53 (0.96, 2.42) |
2.08 (1.01, 4.29)
| 1.26 (0.54, 2.95) |
No onset of use disorder | 6975 (78.26) |
Reference
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Reference
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Reference
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Reference
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C. Age of onset of alcohol dependence disorder
| |||||
Very early (Q1: 12-17 y) | 66 (0.86) |
3.63 (1.84, 7.17)
| 1.69 (0.82, 3.49) |
8.73 (3.33, 22.91)
|
3.51 (1.29, 9.52)
|
Early (Q2:18-20y) | 100 (1.07) | 1.19 (0.66, 2.15) | 0.71 (0.39, 1.29) | 2.18 (0.84, 5.65) | 1.14 (0.45, 2.82) |
Middle (Q3: 21-29y) | 75 (0.85) |
4.45 (1.79, 11.05)
| 1.99 (0.79, 5.02) |
3.23 (1.16, 8.99)
| 1.18 (0.36, 3.88) |
Late (Q4: 30-79y) | 83 (0.84) |
7.12 (2.97, 17.09)
|
4.29 (1.24, 14.89)
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5.51 (131, 23.27)
| 2.84 (0.46, 17.66) |
No onset | 8449 (96.39) |
Reference
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Reference
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Reference
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Reference
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