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01.12.2017 | Research | Ausgabe 1/2017 Open Access

International Journal for Equity in Health 1/2017

The association of early life socioeconomic conditions with prediabetes and type 2 diabetes: results from the Maastricht study

Zeitschrift:
International Journal for Equity in Health > Ausgabe 1/2017
Autoren:
Ivonne P. M. Derks, Annemarie Koster, Miranda T. Schram, Coen D. A. Stehouwer, Pieter C. Dagnelie, Danielle A. I. Groffen, Hans Bosma
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​s12939-017-0553-7) contains supplementary material, which is available to authorized users.

Abstract

Background

Using cross-sectional data from The Maastricht Study, we examined the association of socioeconomic conditions in early life with prediabetes and T2DM in adulthood. We also examined potential mediating pathways via both adulthood socioeconomic conditions and adult BMI and health behaviours.

Methods

Of the 3263 participants (aged 40–75 years), 493 had prediabetes and 906 were diagnosed with T2DM. By using logistic regression analyses, the associations and possible mediating pathways were examined.

Results

Participants with low early life socioeconomic conditions had a 1.56 times higher odds of prediabetes (95% confidence interval (CI) = 1.21-2.02) and a 1.61 times higher odds of T2DM (95% CI = 1.31-1.99). The relation between low early life socioeconomic conditions and prediabetes was independent of current socioeconomic conditions (OR = 1.38, 95% CI = 1.05-1.80), whereas the relation with T2DM was not independent of current socioeconomic conditions (OR = 1.10, 95% CI = 0.87-1.37). BMI party mediated the association between early life socioeconomic conditions and prediabetes.

Conclusions

Socioeconomic inequalities starting in early life were associated with diabetes-related outcomes in adulthood and suggest the usefulness of early life interventions aimed at tackling these inequalities.
Zusatzmaterial
Additional file 1: Table S1. Associations between early life socioeconomic conditions and health behaviour and BMI, n = 3263. (PDF 146 kb)
12939_2017_553_MOESM1_ESM.pdf
Additional file 2: Associations between BMI, health behaviour and current socioeconomic conditions with diabetes status. (PDF 145 kb)
12939_2017_553_MOESM2_ESM.pdf
Additional file 3: Table S3. Odds ratios for newly diagnosed diabetes by early life socioeconomic conditions. (PDF 146 kb)
12939_2017_553_MOESM3_ESM.pdf
Literatur
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