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01.12.2023

The associations between short-term exposure to ambient particulate matter and hospitalizations for osteoporotic fracture in Hangzhou: a time-stratified case-crossover study

verfasst von: Faxue Zhang, Xupeng Zhang, Shijie Zhu, Gaichan Zhao, Tianzhou Li, Aojing Han, Xiaowei Zhang, Tingxiao Zhao, Dejia Li, Wei Zhu

Erschienen in: Archives of Osteoporosis | Ausgabe 1/2023

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Abstract

Summary

Our results suggested that short-term exposure to particulate matter (PM) might increase the risks of hospitalizations for osteoporotic fractures. Government should protect its citizens by putting in place policies to reduce unhealthy emissions and air pollution.

Introduction

Osteoporotic fractures are accompanied by high rates of disability and mortality. PM has been linked with many health outcomes. However, few studies focus on the association of short-term exposure to ambient PM and osteoporotic fractures.

Methods

Data on daily mean air pollution, meteorological factors, and hospitalizations for osteoporotic fractures were collected from Hangzhou, China, 2020–2021. A time-stratified case-crossover design with extended Cox proportional hazards regression was applied to assess the associations between PM and osteoporotic fractures.

Results

Short-term exposure to PM significantly increased the risks of hospitalizations for osteoporotic fractures at cumulative lag days. Per 10 μg/m³ increased in PM_2.5 (PM with an aerodynamic diameter ≤ 2.5 μm), PM_C (PM with an aerodynamic diameter between 2.5 μm and 10 μm), and PM₁₀ (PM with an aerodynamic diameter ≤ 10 μm) were associated with 5.65% (95% confidence intervals (CIs): 1.29, 10.19), 3.19% (0.11, 6.36), and 2.45% (0.57, 4.37) increase in hospitalizations for osteoporotic fractures, respectively. Significant PM-osteoporotic fracture associations were only observed in females and people aged over 65 years old. For the season, the estimates of PM on hospitalizations for osteoporotic fractures were 6.30% (95% CIs: 1.62, 11.20) in the cold season vs. 2.16% (95% CIs: − 4.62, 9.42) in the warm season for per 10 μg/m³ increase of PM_2.5, and 0.99 (95% CIs: − 2.69, 4.80) vs. 6.72% (95% CIs: 0.68, 13.13) for PM_C.

Conclusions

Our study showed PM was positively linked with the risk of osteoporotic fractures. Females and people aged over 65 years old were more susceptible to PM. The adverse impacts of PM_2.5 in the cold season and PM_C in the warm season were worthy of special attention.

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Titel: The associations between short-term exposure to ambient particulate matter and hospitalizations for osteoporotic fracture in Hangzhou: a time-stratified case-crossover study
verfasst von: Faxue Zhang
Xupeng Zhang
Shijie Zhu
Gaichan Zhao
Tianzhou Li
Aojing Han
Xiaowei Zhang
Tingxiao Zhao
Dejia Li
Wei Zhu
Publikationsdatum: 01.12.2023
Verlag: Springer London
Erschienen in: Archives of Osteoporosis / Ausgabe 1/2023
Print ISSN: 1862-3522
Elektronische ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-022-01192-9

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The associations between short-term exposure to ambient particulate matter and hospitalizations for osteoporotic fracture in Hangzhou: a time-stratified case-crossover study

Abstract

Summary

Introduction

Methods

Results

Conclusions

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Abstract

Summary

Introduction

Methods

Results

Conclusions

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