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Intensive Care Medicine

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23.03.2016 | Editorial

The Berlin definition met our needs: not sure

verfasst von: Jean-Louis Vincent

Erschienen in: Intensive Care Medicine | Ausgabe 5/2016

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Excerpt

I was fortunate to be one of the participants involved in elaborating the new criteria for the acute respiratory distress syndrome (ARDS) in Berlin in 2012 [1]. I appreciated the discussions during this process and support the outcome. At the same time, I respectfully wonder whether this intellectual performance really helps our patients. Developing new definitions may appear to bring some uniformity to the patient populations included in clinical trials, but it does not eliminate the underlying heterogeneity; it may, therefore, actually contribute to generate additional negative trials. So are these new ARDS definitions really a major advance? …

Ferguson ND, Fan E, Camporota L, Antonelli M, Anzueto A, Beale R, Brochard L, Brower R, Esteban A, Gattinoni L, Rhodes A, Slutsky AS, Vincent JL, Rubenfeld GD, Thompson BT, Ranieri VM (2012) The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med 38:1573–1582CrossRefPubMed

Bellani G, Laffey JG, Pham T, Fan E, Brochard L, Esteban A, Gattinoni L, van HF, Larsson A, McAuley DF, Ranieri M, Rubenfeld G, Thompson BT, Wrigge H, Slutsky AS, Pesenti A (2016) Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA 315:788–800CrossRefPubMed

Vincent JL, Santacruz C (2016) Do we need ARDS? Intensive Care Med 42:282–283CrossRefPubMed

Sutherasan Y, Vargas M, Pelosi P (2014) Protective mechanical ventilation in the non-injured lung: review and meta-analysis. Crit Care 18:211CrossRefPubMedPubMedCentral

Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, Zhou Q, Matte A, Walter SD, Lamontagne F, Granton JT, Arabi YM, Arroliga AC, Stewart TE, Slutsky AS, Meade MO (2013) High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med 368:795–805CrossRefPubMed

Vincent JL, Santacruz C (2015) Traitement de l’ARDS: Ce qui est basé sur l’évidence. Communications Scientifiques 2015. MAPAR Editions, Le Kremlin Bicêtre, pp 177–180

de Hemptinne Q, Remmelink M, Brimioulle S, Salmon I, Vincent JL (2009) ARDS: a clinicopathological confrontation. Chest 135:944–949CrossRefPubMed

Lorente JA, Cardinal-Fernandez P, Munoz D, Frutos-Vivar F, Thille AW, Jaramillo C, Ballen-Barragan A, Rodriguez JM, Penuelas O, Ortiz G, Blanco J, Pinheiro BV, Nin N, Del Carmen MM, Esteban A, Thompson TB (2015) Acute respiratory distress syndrome in patients with and without diffuse alveolar damage: an autopsy study. Intensive Care Med 41:1921–1930. doi:10.1007/s00134-015-4046-0 CrossRefPubMed

Kao KC, Hu HC, Chang CH, Hung CY, Chiu LC, Li SH, Lin SW, Chuang LP, Wang CW, Li LF, Chen NH, Yang CT, Huang CC, Tsai YH (2015) Diffuse alveolar damage associated mortality in selected acute respiratory distress syndrome patients with open lung biopsy. Crit Care 19:228CrossRefPubMedPubMedCentral

10.

Guerin C, Bayle F, Leray V, Debord S, Stoian A, Yonis H, Roudaut JB, Bourdin G, Devouassoux-Shisheboran M, Bucher E, Ayzac L, Lantuejoul S, Philipponnet C, Kemeny JL, Souweine B, Richard JC (2015) Open lung biopsy in nonresolving ARDS frequently identifies diffuse alveolar damage regardless of the severity stage and may have implications for patient management. Intensive Care Med 41:222–230. doi:10.1007/s00134-014-3583-2 CrossRefPubMed

11.

Vincent JL, Mira JP, Antonelli M (2016) Sepsis: older and newer concepts. Lancet Respir Med 4:237–240CrossRefPubMed

12.

Vincent JL (2016) Individual gene expression and personalised medicine in sepsis. Lancet Respir Med. doi:10.1016/S2213-2600(16)00068-0

Titel: The Berlin definition met our needs: not sure
verfasst von: Jean-Louis Vincent
Publikationsdatum: 23.03.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 5/2016
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-016-4319-2

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