To investigate variables associated at one year (longitudinal design) with the physical or emotional component of burden in chronic tension type headache (CTTH).
One hundred and thirty (n = 130) individuals with CTTH participated in this longitudinal study. Clinical features were collected with a 4-weeks headache diary at baseline and 1-year follow-up. The burden of headache was assessed at baseline and one -year follow-up with the Headache Disability Inventory (HDI), physical (HDI-P) or emotional (HDI-E) component. Sleep quality (Pittsburgh Sleep Quality Index), anxiety and depression (Hospital Anxiety and Depression Scale-HADS), and quality of life (SF-36) were also assessed at baseline. Hierarchical regression analyses were conducted to determine the associations between the baseline variables and the headache burden at 1-year. Simple mediation models were also applied to determine the potential mediation effect of any intermediary variable.
Regression analyses revealed that baseline pain interference and depression explained 32% of the variance in the emotional burden of headache, whereas baseline emotional burden of the headache, pain interference, and headache duration explained 51% of the variance in the physical burden of headache (P < .01) at 1-year. The mediation models observed that the effect of baseline pain interference on emotional burden of headache at 1-year was mediated through baseline depression, whereas the effect of baseline pain interference on the physical burden of headache at 1-year was mediated through baseline emotional burden of headache (both P < .05).
The current study found a longitudinal interaction between pain interference and depression with the burden of headache in individuals with CTTH.
Dowson A (2015) The burden of headache: global and regional prevalence of headache and its impact. Int J Clin Pract Suppl 182:3–7 CrossRef
GBD 2016 Disease and Injury Incidence and Prevalence Collaborators (2017) Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the global burden of disease study 2016. Lancet 390:1211–1259 CrossRef
Zebenholzer K, Lechner A, Broessner G, Lampl C, Luthringshausen G, Wuschitz A, Obmann SM, Berek K, Wöber C (2016) Impact of depression and anxiety on burden and management of episodic and chronic headaches - a cross-sectional multicentre study in eight Austrian headache centres. J Headache Pain 17:15 CrossRefPubMedPubMedCentral
Palacios-Ceña M, Fernández-Muñoz JJ, Castaldo M, Wang K, Guerrero-Peral Á, Arendt-Nielsen L, Fernández-de-las-Peñas C (2017) The association of headache frequency with pain interference and the burden of disease is mediated by depression and sleep quality, but not anxiety, in chronic tension type headache. J Headache Pain 18:19 CrossRefPubMedPubMedCentral
ICHD-III (2013) International classification of headache disorder: headache classification Subcommittee of the International Headache Society, 3nd edition. Cephalalgia 33:629–808 CrossRef
Jensen R, Tassorelli C, Rossi P, Allena M, Osipova V, Steiner T, Sandrini G, Olesen J, Nappi G, Basic Diagnostic Headache Diary Study Group (2011) A basic diagnostic headache headache diary (BDHD) is well accepted and useful in the diagnosis of headache. A multicentre European and Latin American study. Cephalalgia 31:1549–1560 CrossRefPubMed
Herrmann-Lingen C, Buss U, Snaith R (2011) Hospital Anxiety and Depression Scale – Deutsche Version (HADS-D) Verlag Hans Huber, Bern
Juang KD, Wang SJ, Lin CH, Fuh JL (1999) Use of the hospital anxiety and depression scale as a screening tool for patients with headache. Zhonghua Yi Xue Za Zhi (Taipei) 62:749–755
Baron RM, Kenny DA (1986) The moderator-mediator variable distinction in social psychological research: conceptual, strategic and statistical considerations. J Personality Social Psychol 51:1173–1182 CrossRef
Hayes AF (2013) Introduction to mediation, moderation and conditional process analysis. A regression based approach. The Guilford Press, Nueva York
- The burden of headache is associated to pain interference, depression and headache duration in chronic tension type headache: a 1-year longitudinal study
Juan J. Fernández-Muñoz
- Springer Milan
Neu im Fachgebiet AINS
Meistgelesene Bücher aus dem Fachgebiet AINS
Mail Icon II