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Erschienen in: Langenbeck's Archives of Surgery 4/2008

01.07.2008 | Overview

The challenge of pancreatic anastomosis

verfasst von: Axel Kleespies, Markus Albertsmeier, Firas Obeidat, Hendrik Seeliger, Karl-Walter Jauch, Christiane J. Bruns

Erschienen in: Langenbeck's Archives of Surgery | Ausgabe 4/2008

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Abstract

Background and aims

Significant progress in surgical technique and perioperative management has substantially reduced the mortality rate of pancreatic surgery. However, morbidity remains considerably high, even in expert hands and leakage from the pancreatic stump still accounts for the majority of surgical complications after pancreatic head resection. For that reason, management of the pancreatic remnant after partial pancreatoduodenectomy remains a challenge. This review will focus on technique, pitfalls, and complication management of pancreaticoenteric anastomoses.

Materials and methods

A medline search for surgical guidelines, prospective randomized controlled trials, systematic metaanalysis, and clinical reports was performed with regard to surgical technique and complication management of pancreatic anastomoses.

Results

Pancreaticojejunostomy appears to be most widely performed, but pancreaticogastrostomy is a reasonable alternative. Postoperative treatment with octreotide can be recommended only for patients with soft pancreatic tissue, and neither stents of the pancreatic duct nor drainages have proven to effectively reduce anastomotic complications. Gastroparesis remains the most common complication after pancreatic surgery and should be treated conservatively. However, it may be a symptom of other local complications, such as anastomotic leakage, pancreatic fistula or abscess. All septic complications may finally result in late postoperative hemorrhage, which requires immediate diagnostic workup and therapy. Today, interventional radiology has emerged as a standard tool in the management of local septic complications and bleeding. Therefore, relaparotomy has become less frequent and salvage pancreatectomy is now a rare procedure in case of local complications.

Conclusion

The surgeon’s experience with one or the other technique of pancreatic anastomosis appears to be more important than the technique itself.
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Metadaten
Titel
The challenge of pancreatic anastomosis
verfasst von
Axel Kleespies
Markus Albertsmeier
Firas Obeidat
Hendrik Seeliger
Karl-Walter Jauch
Christiane J. Bruns
Publikationsdatum
01.07.2008
Verlag
Springer-Verlag
Erschienen in
Langenbeck's Archives of Surgery / Ausgabe 4/2008
Print ISSN: 1435-2443
Elektronische ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-008-0324-4