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Erschienen in: Irish Journal of Medical Science (1971 -) 3/2018

24.01.2018 | Original Article

The clinical utility of pre-operative neutrophil-to-lymphocyte ratio as a predictor of outcomes in patients undergoing elective laparoscopic cholecystectomy

verfasst von: Brian M. Moloney, Ronan M. Waldron, Niamh O’ Halloran, Michael E. Kelly, Eddie Myers, Joseph T. Garvin, Michael J. Kerin, Chris G. Collins

Erschienen in: Irish Journal of Medical Science (1971 -) | Ausgabe 3/2018

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Abstract

Background

In recent years, there has been an increasing trend towards day-case surgery for patients undergoing laparoscopic cholecystectomy (LC). We investigated the predictive value that pre-operative neutrophil-to-lymphocyte ratio (PNLR) had on surgical outcomes.

Methods

A review of all patients who underwent LC during a 6-year period in a single institution was performed and PNLR recorded. A PNLR cutoff value of 3 was utilised. We compared operation time, length of stay (LOS), and conversion to open between those with PNLR less and greater than 3.

Results

A total of 567 patients underwent elective LC. Those with PNLR>3 had associated prolonged operation time (p < 0.005), prolonged LOS (p < 0.005), and higher rates of conversion to open surgery (p < 0.005).

Conclusions

PNLR correlates with outcomes following LC. It is useful in delineating patients that have higher risk of conversion or prolonged length of hospital stay and is helpful in assessing suitability of day-case surgery.
Literatur
9.
Zurück zum Zitat Dirksen CD, Schmitz RF, Hans KM, Nieman FH, Hoogenboom LJ, Go PM (2001) Ambulatory laparoscopic cholecystectomy is as effective as hospitalization and from a social perspective less expensive: a randomized study. Ned Tijdschr Geneeskd 145(50):2434–2439PubMed Dirksen CD, Schmitz RF, Hans KM, Nieman FH, Hoogenboom LJ, Go PM (2001) Ambulatory laparoscopic cholecystectomy is as effective as hospitalization and from a social perspective less expensive: a randomized study. Ned Tijdschr Geneeskd 145(50):2434–2439PubMed
11.
Zurück zum Zitat Kelly ME, Khan A, Riaz M, Bolger JC, Bennani F, Khan W, Waldron R, Khan IZ, Barry K (2015) The utility of neutrophil-to-lymphocyte ratio as a severity predictor of acute appendicitis, length of hospital stay and postoperative complication rates. Dig Surg 32(6):459–463. https://doi.org/10.1159/000440818 CrossRefPubMed Kelly ME, Khan A, Riaz M, Bolger JC, Bennani F, Khan W, Waldron R, Khan IZ, Barry K (2015) The utility of neutrophil-to-lymphocyte ratio as a severity predictor of acute appendicitis, length of hospital stay and postoperative complication rates. Dig Surg 32(6):459–463. https://​doi.​org/​10.​1159/​000440818 CrossRefPubMed
17.
Zurück zum Zitat Petrie HT, Klassen LW, Kay HD (1985) Inhibition of human cytotoxic T lymphocyte activity in vitro by autologous peripheral blood granulocytes. J Immunol 134(1):230–234PubMed Petrie HT, Klassen LW, Kay HD (1985) Inhibition of human cytotoxic T lymphocyte activity in vitro by autologous peripheral blood granulocytes. J Immunol 134(1):230–234PubMed
18.
Zurück zum Zitat TVK KH, Bhaskaran A, Jaswanthi AR (2017) Neutrophil to lymphocyte ratio in diagnosing acute cholecystitis: a retrospective cohort study in a tertiary rural hospital. Int Surger J 4(1):4 TVK KH, Bhaskaran A, Jaswanthi AR (2017) Neutrophil to lymphocyte ratio in diagnosing acute cholecystitis: a retrospective cohort study in a tertiary rural hospital. Int Surger J 4(1):4
23.
Zurück zum Zitat Beliaev AM et al (2016) Evaluation of neutrophil-to-lymphocyte ratio as a potential biomarker for acute cholecystitis. J Surg Res 209:93–101CrossRefPubMed Beliaev AM et al (2016) Evaluation of neutrophil-to-lymphocyte ratio as a potential biomarker for acute cholecystitis. J Surg Res 209:93–101CrossRefPubMed
26.
Zurück zum Zitat Liu X et al (2016) Prognostic significance of neutrophil-to-lymphocyte ratio in patients with sepsis: a prospective observational study. Mediat Inflamm 2016:8191254 Liu X et al (2016) Prognostic significance of neutrophil-to-lymphocyte ratio in patients with sepsis: a prospective observational study. Mediat Inflamm 2016:8191254
27.
Zurück zum Zitat BADS (2009), British Association of Day Case Surgery - Directory of procedures. Third ed. London BADS (2009), British Association of Day Case Surgery - Directory of procedures. Third ed. London
28.
Zurück zum Zitat Reynolds I, Bolger J, al -Hilli Z, Hill AD (2015) Breaking barriers to successful implementation of day case laparoscopic cholecystectomy. Ir Med J 108(7):202–204PubMed Reynolds I, Bolger J, al -Hilli Z, Hill AD (2015) Breaking barriers to successful implementation of day case laparoscopic cholecystectomy. Ir Med J 108(7):202–204PubMed
29.
Zurück zum Zitat Ji W, Ding K, Li LT, Wang D, Li N, Li JS (2010) Outpatient versus inpatient laparoscopic cholecystectomy: a single center clinical analysis. Hepatobiliary Pancreat Dis Int 9(1):60–64PubMed Ji W, Ding K, Li LT, Wang D, Li N, Li JS (2010) Outpatient versus inpatient laparoscopic cholecystectomy: a single center clinical analysis. Hepatobiliary Pancreat Dis Int 9(1):60–64PubMed
Metadaten
Titel
The clinical utility of pre-operative neutrophil-to-lymphocyte ratio as a predictor of outcomes in patients undergoing elective laparoscopic cholecystectomy
verfasst von
Brian M. Moloney
Ronan M. Waldron
Niamh O’ Halloran
Michael E. Kelly
Eddie Myers
Joseph T. Garvin
Michael J. Kerin
Chris G. Collins
Publikationsdatum
24.01.2018
Verlag
Springer London
Erschienen in
Irish Journal of Medical Science (1971 -) / Ausgabe 3/2018
Print ISSN: 0021-1265
Elektronische ISSN: 1863-4362
DOI
https://doi.org/10.1007/s11845-018-1749-6

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