Skip to main content
Erschienen in: The International Journal of Cardiovascular Imaging 1/2019

21.08.2018 | Original Paper

The comparison of short-term prognostic value of T1 mapping with feature tracking by cardiovascular magnetic resonance in patients with severe dilated cardiomyopathy

verfasst von: Rui Chen, Jingjing Wang, Zhicheng Du, Yu-Hsiang Juan, Carmen Wing-Sze Chan, Hongwen Fei, Jiajun Xie, Wanjia Wu, Yulei Zhu, Liwen Li, Jinxiu Meng, Shulin Wu, Changhong Liang, Zhuliang Yu, Hui Liu

Erschienen in: The International Journal of Cardiovascular Imaging | Ausgabe 1/2019

Einloggen, um Zugang zu erhalten

Abstract

To evaluate and compare the prognostic value of T1 mapping with feature tracking cardiovascular magnetic resonance (FT-CMR) imaging in patients with severe dilated cardiomyopathy (DCM) during short-term follow-up. A total of 46 patients with severe DCM (LVEF < 35%) underwent 3.0-T CMR with T1 mapping and FT-CMR analysis. The study end-point was defined as a combination of cardiac death, heart transplantation, and hospitalization due to cardiovascular events. The significance of the risk factors was mainly evaluated by univariate and multivariate Cox model analyses. During the median follow-up of 13 months (interquartile range 7–17 months), two patients died of heart failure, one received a heart transplantation, and six were hospitalized for heart failure. In the univariate analysis, extracellular volume fraction (ECV) showed significant predictive association with cardiovascular events (hazard ratio [HR] 1.35; 95% confidence interval [CI] 1.13–1.62; P = 0.001). No strain parameters in FT-CMR differed significantly between patients with or without events (all P > 0.05). In the multivariate analyses, ECV was the sole independent predictor of cardiovascular events (HR, 1.48; 95% CI 1.13–1.94; P = 0.005). The area under the curve of the time-dependent receiver operating characteristic in leave-one-out cross-validation (all > 0.70) further confirmed the predictive significance of ECV. In patients with severe DCM, ECV was not only a strong independent predictor of adverse cardiovascular events but also provided prognostic value prior to strain parameters of the FT-CMR in the short term.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
3.
Zurück zum Zitat McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Bohm M, Dickstein K et al (2012) ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J 33:1787–1847. https://doi.org/10.1093/eurjhf/hfs105 CrossRefPubMed McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Bohm M, Dickstein K et al (2012) ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J 33:1787–1847. https://​doi.​org/​10.​1093/​eurjhf/​hfs105 CrossRefPubMed
8.
Zurück zum Zitat Nagueh SF, Smiseth OA, Appleton CP, Byrd BF 3rd, Dokainish H, Edvardsen T et al (2016) Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American Society of Echocardiography and the European Association of cardiovascular imaging. Eur Heart J 17:1321–1360. https://doi.org/10.1093/ehjci/jew082 CrossRef Nagueh SF, Smiseth OA, Appleton CP, Byrd BF 3rd, Dokainish H, Edvardsen T et al (2016) Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American Society of Echocardiography and the European Association of cardiovascular imaging. Eur Heart J 17:1321–1360. https://​doi.​org/​10.​1093/​ehjci/​jew082 CrossRef
9.
Zurück zum Zitat Buss SJ, Breuninger K, Lehrke S, Voss A, Galuschky C, Lossnitzer D et al (2015) Assessment of myocardial deformation with cardiac magnetic resonance strain imaging improves risk stratification in patients with dilated cardiomyopathy. Eur Heart J 16:307–315. https://doi.org/10.1093/ehjci/jeu181 CrossRef Buss SJ, Breuninger K, Lehrke S, Voss A, Galuschky C, Lossnitzer D et al (2015) Assessment of myocardial deformation with cardiac magnetic resonance strain imaging improves risk stratification in patients with dilated cardiomyopathy. Eur Heart J 16:307–315. https://​doi.​org/​10.​1093/​ehjci/​jeu181 CrossRef
11.
Zurück zum Zitat Moon JCMD, Kellman P, Piechnik SK, Robson MD, Ugander M, Gatehouse PD, Arai AE, Friedrich MG, Neubauer S, Schulz-Menger J, Schelbert EB (2013) Myocardial T1 mapping and extracellular volume quantification: a society for Cardiovascular Magnetic Resonance (SCMR) and CMR Working Group of the European Society of Cardiology consensus statement. J Cardiovasc Magn Reson 15:92. https://doi.org/10.1186/1532-429X-15-92 CrossRefPubMedPubMedCentral Moon JCMD, Kellman P, Piechnik SK, Robson MD, Ugander M, Gatehouse PD, Arai AE, Friedrich MG, Neubauer S, Schulz-Menger J, Schelbert EB (2013) Myocardial T1 mapping and extracellular volume quantification: a society for Cardiovascular Magnetic Resonance (SCMR) and CMR Working Group of the European Society of Cardiology consensus statement. J Cardiovasc Magn Reson 15:92. https://​doi.​org/​10.​1186/​1532-429X-15-92 CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat aus dem Siepen F, Buss SJ, Messroghli D, Andre F, Lossnitzer D, Seitz S, Keller M et al (2014) T1 mapping in dilated cardiomyopathy with cardiac magnetic resonance: quantification of diffuse myocardial fibrosis and comparison with endomyocardial biopsy. Eur Heart J 16:210–216. https://doi.org/10.1093/ehjci/jeu183 CrossRef aus dem Siepen F, Buss SJ, Messroghli D, Andre F, Lossnitzer D, Seitz S, Keller M et al (2014) T1 mapping in dilated cardiomyopathy with cardiac magnetic resonance: quantification of diffuse myocardial fibrosis and comparison with endomyocardial biopsy. Eur Heart J 16:210–216. https://​doi.​org/​10.​1093/​ehjci/​jeu183 CrossRef
20.
21.
22.
Zurück zum Zitat Arenja NRJ, Fritz T, Andre F, Siepen F, Mueller-Hennessen MGE, Katus HA, Friedrich MG, Buss SJ (2017) Diagnostic and prognostic value of long-axis strain and myocardial contraction fraction using standard cardiovascular MR imaging in patients with nonischemic dilated cardiomyopathies. Radiology 283:681–691. https://doi.org/10.1148/radiol.2016161184 CrossRefPubMed Arenja NRJ, Fritz T, Andre F, Siepen F, Mueller-Hennessen MGE, Katus HA, Friedrich MG, Buss SJ (2017) Diagnostic and prognostic value of long-axis strain and myocardial contraction fraction using standard cardiovascular MR imaging in patients with nonischemic dilated cardiomyopathies. Radiology 283:681–691. https://​doi.​org/​10.​1148/​radiol.​2016161184 CrossRefPubMed
Metadaten
Titel
The comparison of short-term prognostic value of T1 mapping with feature tracking by cardiovascular magnetic resonance in patients with severe dilated cardiomyopathy
verfasst von
Rui Chen
Jingjing Wang
Zhicheng Du
Yu-Hsiang Juan
Carmen Wing-Sze Chan
Hongwen Fei
Jiajun Xie
Wanjia Wu
Yulei Zhu
Liwen Li
Jinxiu Meng
Shulin Wu
Changhong Liang
Zhuliang Yu
Hui Liu
Publikationsdatum
21.08.2018
Verlag
Springer Netherlands
Erschienen in
The International Journal of Cardiovascular Imaging / Ausgabe 1/2019
Print ISSN: 1569-5794
Elektronische ISSN: 1875-8312
DOI
https://doi.org/10.1007/s10554-018-1444-8

Weitere Artikel der Ausgabe 1/2019

The International Journal of Cardiovascular Imaging 1/2019 Zur Ausgabe

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.