Background
Methods
General approach
Data sources
Estimation methods
Sensitivity analyses
Results
Total deaths, world age-standardised mortality rates (WASRs) and YPPLL by gender
ICD10 | Cancer site | All deaths | % of the total | WASR per 100,000 | % of the total | YPPLL | % of the total |
---|---|---|---|---|---|---|---|
Males
| |||||||
C00-97,B21
|
All cancers
|
4,276
|
-
|
140.0
|
-
|
10,873
|
-
|
Top 10 cancers
|
3,272
|
76.5
|
-
|
-
|
7,453
|
68.5
| |
C15 | Oesophagus | 218 | 5.1 | 7.4 | 5.3 | 598 | 5.5 |
C16 | Stomach | 207 | 4.8 | 6.8 | 4.9 | 550 | 5.1 |
C18-21 | Colorectal | 554 | 13.0 | 17.9 | 12.8 | 1,211 | 11.1 |
C25 | Pancreas | 217 | 5.1 | 7.4 | 5.3 | 603 | 5.5 |
C33-34 | Lung | 994 | 23.4 | 33.0 | 23.6 | 2,089 | 19.2 |
C61 | Prostate | 530 | 12.4 | 15.6 | 11.1 | 207 | 1.9 |
C67 | Bladder | 121 | 2.8 | 3.7 | 12.6 | 151 | 1.4 |
C70-72 | Brain & CNS | 150 | 3.5 | 5.6 | 74.0 | 1,027 | 9.4 |
C82-85,C96 | Non-Hodgkin’s lymphoma | 132 | 3.1 | 4.4 | 3.1 | 520 | 4.8 |
C91-95 | Leukaemia | 150 | 3.5 | 5.0 | 3.6 | 499 | 4.6 |
Females
| |||||||
C00-97, B21
|
All cancers
|
3,791
|
-
|
104.1
|
-
|
12,119
|
-
|
Top 10 cancers
|
2,860
|
75.4
|
-
|
-
|
9,595
|
79.2
| |
C15 | Oesophagus | 118 | 3.1 | 2.8 | 2.7 | 178 | 1.5 |
C16 | Stomach | 130 | 3.4 | 3.3 | 3.2 | 334 | 2.8 |
C18-21 | Colorectal | 401 | 10.6 | 10.0 | 9.6 | 856 | 7.1 |
C25 | Pancreas | 218 | 5.8 | 5.5 | 5.3 | 361 | 3.0 |
C33-34 | Lung | 668 | 17.6 | 18.6 | 17.9 | 1,542 | 12.7 |
C50 | Breast | 679 | 17.9 | 20.5 | 19.7 | 3,329 | 27.5 |
C53-55 | Uterus | 172 | 4.5 | 5.5 | 5.3 | 1,126 | 9.3 |
C56 | Ovary | 254 | 6.7 | 7.7 | 7.4 | 901 | 7.4 |
C70-72 | Brain & CNS | 109 | 2.9 | 3.6 | 3.5 | 683 | 5.6 |
C82-85,C96 | Non-Hodgkin’s lymphoma | 111 | 2.9 | 2.8 | 2.7 | 288 | 2.4 |
Base-case analyses: total premature mortality costs, overall and by gender
ICD10 | Cancer site | Total premature mortality cost | % of the total | Premature mortality cost per death | Premature mortality cost per YPPLL |
---|---|---|---|---|---|
Males
| |||||
C00-97,B21
|
All cancers
|
332,246,992
|
-
|
290,172
|
30,558
|
Top 10 cancers
|
228,125,322
|
68.7
|
276,918
|
31,381
| |
C15 | Oesophagus | 18,564,734 | 5.6 | 268,276 | 31,045 |
C16 | Stomach | 17,294,647 | 5.2 | 315,596 | 31,445 |
C18-21 | Colorectal | 37,253,268 | 11.2 | 276,770 | 30,775 |
C25 | Pancreas | 18,624,081 | 5.6 | 263,797 | 30,911 |
C33-34 | Lung | 62,927,480 | 18.9 | 220,953 | 30,123 |
C61 | Prostate | 5,950,929 | 1.8 | 154,169 | 28,818 |
C67 | Bladder | 4,637,827 | 1.4 | 246,693 | 30,714 |
C70-72 | Brain & CNS | 32,011,173 | 9.6 | 421,200 | 32,367 |
C82-85,C96 | Non-Hodgkin’s lymphoma | 16,113,046 | 4.8 | 385,480 | 36,579 |
C91-95 | Leukaemia | 14,748,138 | 4.4 | 426,247 | 34,100 |
Females
| |||||
C00-97,B21
|
All cancers
|
177,266,357
|
-
|
159,959
|
14,628
|
Top 10 cancers
|
139,871,322
|
78.9
|
155,275
|
14,578
| |
C15 | Oesophagus | 2,442,679 | 1.4 | 118,577 | 13,762 |
C16 | Stomach | 4,985,032 | 2.8 | 178,037 | 14,925 |
C18-21 | Colorectal | 12,393,845 | 7.0 | 147,195 | 14,487 |
C25 | Pancreas | 4,847,345 | 2.7 | 105,377 | 13,428 |
C33-34 | Lung | 21,099,185 | 11.9 | 114,919 | 13,683 |
C61 | Breast | 49,395,514 | 27.9 | 172,350 | 14,840 |
C67 | Uterus | 17,291,434 | 9.8 | 208,331 | 15,363 |
C70-72 | Ovary | 12,862,247 | 7.3 | 141,343 | 14,283 |
C82-85,C96 | Brain & CNS | 10,370,158 | 5.9 | 202,542 | 15,183 |
C91-95 | Non-Hodgkin’s lymphoma | 4,183,884 | 2.4 | 157,289 | 14,553 |
Premature mortality cost per death and per YPPLL
Gender distribution of YPPLL and premature mortality costs by age
Sensitivity analysis
Male | Female | |||||
---|---|---|---|---|---|---|
Total premature mortality cost | % change from BC | Premature mortality cost per death | Total premature mortality cost | % change from BC | Premature mortality cost per death | |
BC
|
332,246,992
|
-
|
290,172
|
177,266,357
|
-
|
159,959
|
Wage growth (BC: 2.6%)
| ||||||
1.50%
| 307,469,158 | (-7.5) | 268,532 | 164,171,979 | (-7.4) | 148,143 |
3.50%
| 353,158,857 | (+6.3) | 308,436 | 189,439,743 | (+6.9) | 170,944 |
Discount rate (BC: 4%)
| ||||||
2%
| 384,579,486 | (+15.8) | 335,877 | 206,654,039 | (+16.6) | 186,477 |
6%
| 291,598,265 | (-12.2) | 254,671 | 155,339,730 | (-12.4) | 140,173 |
Labour force participation & unemployment (BC: 2009 rates)
| ||||||
2013 rates
| 368,598,902 | (+10.9) | 321,920 | 178,709,602 | (+0.8) | 161,261 |
Retirement age (BC: 65)
| ||||||
Age = 66
| 365,157,324 | (+9.9) | 318,915 | 187,656,321 | (+5.9) | 169,334 |
Scenario analysis: Lost household production and caring activity
ICD10 | Cancer site | Total lost household production cost | Total lost caring cost |
---|---|---|---|
Male
| |||
C00-97,B21
|
All cancers
|
68,119,367
|
39,440,641
|
Top 10 cancers
|
47,031,364
|
27,230,833
| |
C15 | Oesophagus | 3,817,270 | 2,210,173 |
C16 | Stomach | 3,459,966 | 2,003,296 |
C18-21 | Colorectal | 7,646,872 | 4,441,163 |
C25 | Pancreas | 3,854,138 | 2,231,519 |
C33-34 | Lung | 13,500,891 | 7,816,922 |
C61 | Prostate | 1,361,957 | 788,564 |
C67 | Bladder | 964,857 | 558,646 |
C70-72 | Brain & CNS | 6,253,721 | 3,620,861 |
C82-85,C96 | Non-Hodgkin’s lymphoma | 3,186,066 | 1,844,710 |
C91-95 | Leukaemia | 2,962,003 | 1,714,979 |
Female
| |||
C00-97,B21
|
All cancers
|
163,592,354
|
165,057,650
|
Top 10 cancers
|
130,228,532
|
131,394,989
| |
C15 | Oesophagus | 2,455,357 | 2,477,349 |
C16 | Stomach | 4,482,568 | 4,522,718 |
C18-21 | Colorectal | 11,646,872 | 11,751,193 |
C25 | Pancreas | 5,044,263 | 5,089,444 |
C33-34 | Lung | 21,421,357 | 21,613,229 |
C61 | Breast | 45,150,884 | 45,555,300 |
C67 | Uterus | 14,988,015 | 15,122,262 |
C70-72 | Ovary | 12,270,087 | 12,379,990 |
C82-85,C96 | Brain & CNS | 8,921,161 | 9,001,068 |
C91-95 | Non-Hodgkin’s lymphoma | 3,847,969 | 3,882,435 |