Skip to main content
Erschienen in: Osteoporosis International 7/2010

01.07.2010 | Original Article

The differences of femoral neck geometric parameters: effects of age, gender and race

verfasst von: F. Zhang, L.-J. Tan, S.-F. Lei, H.-W. Deng

Erschienen in: Osteoporosis International | Ausgabe 7/2010

Einloggen, um Zugang zu erhalten

Abstract

Summary

This study aims at investigating the effects of age, sex, and ethnicity on five femoral neck geometric parameters (FNGPs): femoral neck periosteal diameter, cross-sectional area, cortical thickness, sectional modulus, and buckling ratio and found that the three factors would influence the FNGPs.

Introduction

Bone geometry is one of the most important predictors of bone strength and osteoporotic fractures. This study aims at investigating the effects of age, sex, and ethnicity on five femoral neck geometric parameters (FNGPs): femoral neck periosteal diameter (W), cross-sectional area (CSA), cortical thickness (CT), sectional modulus (Z), and buckling ratio (BR).

Methods

In the studied 861 Caucasian subjects and 3,021 Chinese individuals, CSA, CT, and Z displayed trends of decrease with age, but W and BR showed increasing trends with age in both Chinese and Caucasian females and males (p < 0.05). W, CSA, CT, and Z were significantly higher (p ≤ 0.001) in Caucasians than in Chinese and higher in males than in females except for BR between Chinese males and Chinese females.

Conclusion

In conclusion, the differences of FNGPs according to gender and ethnicity provide important implications in the different prevalence of osteoporotic fracture among different gender and ethnic groups.
Literatur
1.
Zurück zum Zitat Melton LJ III, Atkinson EJ, O'Fallon WM, Wahner HW, Riggs BL (1993) Long-term fracture prediction by bone mineral assessed at different skeletal sites. J Bone Miner Res 8:1227–1233CrossRefPubMed Melton LJ III, Atkinson EJ, O'Fallon WM, Wahner HW, Riggs BL (1993) Long-term fracture prediction by bone mineral assessed at different skeletal sites. J Bone Miner Res 8:1227–1233CrossRefPubMed
2.
Zurück zum Zitat De Laet CE, Van Hout BA, Burger H, Weel AE, Hofman A, Pols HA (1998) Hip fracture prediction in elderly men and women: validation in the Rotterdam study. J Bone Miner Res 13:1587–1593CrossRefPubMed De Laet CE, Van Hout BA, Burger H, Weel AE, Hofman A, Pols HA (1998) Hip fracture prediction in elderly men and women: validation in the Rotterdam study. J Bone Miner Res 13:1587–1593CrossRefPubMed
3.
Zurück zum Zitat Faulkner KG, Cummings SR, Black D, Palermo L, Gluer CC, Genant HK (1993) Simple measurement of femoral geometry predicts hip fracture: the study of osteoporotic fractures. J Bone Miner Res 8:1211–1217CrossRefPubMed Faulkner KG, Cummings SR, Black D, Palermo L, Gluer CC, Genant HK (1993) Simple measurement of femoral geometry predicts hip fracture: the study of osteoporotic fractures. J Bone Miner Res 8:1211–1217CrossRefPubMed
4.
Zurück zum Zitat Ammann P (2005) Strontium ranelate: a novel mode of action leading to renewed bone quality. Osteoporos Int 16(Suppl 1):S11–S15CrossRefPubMed Ammann P (2005) Strontium ranelate: a novel mode of action leading to renewed bone quality. Osteoporos Int 16(Suppl 1):S11–S15CrossRefPubMed
5.
Zurück zum Zitat Pulkkinen P, Partanen J, Jalovaara P, Jamsa T (2004) Combination of bone mineral density and upper femur geometry improves the prediction of hip fracture. Osteoporos Int 15:274–280CrossRefPubMed Pulkkinen P, Partanen J, Jalovaara P, Jamsa T (2004) Combination of bone mineral density and upper femur geometry improves the prediction of hip fracture. Osteoporos Int 15:274–280CrossRefPubMed
6.
Zurück zum Zitat Gnudi S, Sitta E, Fiumi N (2007) Bone density and geometry in assessing hip fracture risk in post-menopausal women. Br J Radiol 80:893–897CrossRefPubMed Gnudi S, Sitta E, Fiumi N (2007) Bone density and geometry in assessing hip fracture risk in post-menopausal women. Br J Radiol 80:893–897CrossRefPubMed
7.
Zurück zum Zitat Chin K, Evans MC, Cornish J, Cundy T, Reid IR (1997) Differences in hip axis and femoral neck length in premenopausal women of Polynesian, Asian and European origin. Osteoporos Int 7:344–347CrossRefPubMed Chin K, Evans MC, Cornish J, Cundy T, Reid IR (1997) Differences in hip axis and femoral neck length in premenopausal women of Polynesian, Asian and European origin. Osteoporos Int 7:344–347CrossRefPubMed
8.
Zurück zum Zitat Cummings SR, Cauley JA, Palermo L, Ross PD, Wasnich RD, Black D, Faulkner KG (1994) Racial differences in hip axis lengths might explain racial differences in rates of hip fracture. Study of Osteoporotic Fractures Research Group. Osteoporos Int 4:226–229CrossRefPubMed Cummings SR, Cauley JA, Palermo L, Ross PD, Wasnich RD, Black D, Faulkner KG (1994) Racial differences in hip axis lengths might explain racial differences in rates of hip fracture. Study of Osteoporotic Fractures Research Group. Osteoporos Int 4:226–229CrossRefPubMed
9.
Zurück zum Zitat Wang XF, Duan Y, Beck TJ, Seeman E (2005) Varying contributions of growth and ageing to racial and sex differences in femoral neck structure and strength in old age. Bone 36:978–986CrossRefPubMed Wang XF, Duan Y, Beck TJ, Seeman E (2005) Varying contributions of growth and ageing to racial and sex differences in femoral neck structure and strength in old age. Bone 36:978–986CrossRefPubMed
10.
Zurück zum Zitat Duan Y, Turner CH, Kim BT, Seeman E (2001) Sexual dimorphism in vertebral fragility is more the result of gender differences in age-related bone gain than bone loss. J Bone Miner Res 16:2267–2275CrossRefPubMed Duan Y, Turner CH, Kim BT, Seeman E (2001) Sexual dimorphism in vertebral fragility is more the result of gender differences in age-related bone gain than bone loss. J Bone Miner Res 16:2267–2275CrossRefPubMed
11.
Zurück zum Zitat Xu L, Lu A, Zhao X, Chen X, Cummings SR (1996) Very low rates of hip fracture in Beijing, People's Republic of China the Beijing Osteoporosis Project. Am J Epidemiol 144:901–907PubMed Xu L, Lu A, Zhao X, Chen X, Cummings SR (1996) Very low rates of hip fracture in Beijing, People's Republic of China the Beijing Osteoporosis Project. Am J Epidemiol 144:901–907PubMed
12.
Zurück zum Zitat Zhang L, Cheng A, Bai Z, Lu Y, Endo N, Dohmae Y, Takahashi HE (2000) Epidemiology of cervical and trochanteric fractures of the proximal femur in 1994 in Tangshan, China. J Bone Miner Metab 18:84–88CrossRefPubMed Zhang L, Cheng A, Bai Z, Lu Y, Endo N, Dohmae Y, Takahashi HE (2000) Epidemiology of cervical and trochanteric fractures of the proximal femur in 1994 in Tangshan, China. J Bone Miner Metab 18:84–88CrossRefPubMed
13.
Zurück zum Zitat Yan L, Zhou B, Prentice A, Wang X, Golden MH (1999) Epidemiological study of hip fracture in Shenyang, People's Republic of China. Bone 24:151–155CrossRefPubMed Yan L, Zhou B, Prentice A, Wang X, Golden MH (1999) Epidemiological study of hip fracture in Shenyang, People's Republic of China. Bone 24:151–155CrossRefPubMed
14.
Zurück zum Zitat Xu H, Long JR, Yang YJ, Deng FY, Deng HW (2006) Genetic determination and correlation of body weight and body mass index (BMI) and cross-sectional geometric parameters of the femoral neck. Osteoporos Int 17:1602–1607CrossRefPubMed Xu H, Long JR, Yang YJ, Deng FY, Deng HW (2006) Genetic determination and correlation of body weight and body mass index (BMI) and cross-sectional geometric parameters of the femoral neck. Osteoporos Int 17:1602–1607CrossRefPubMed
15.
Zurück zum Zitat Ross PD, Norimatsu H, Davis JW, Yano K, Wasnich RD, Fujiwara S, Hosoda Y, Melton LJ III (1991) A comparison of hip fracture incidence among native Japanese, Japanese Americans, and American Caucasians. Am J Epidemiol 133:801–809PubMed Ross PD, Norimatsu H, Davis JW, Yano K, Wasnich RD, Fujiwara S, Hosoda Y, Melton LJ III (1991) A comparison of hip fracture incidence among native Japanese, Japanese Americans, and American Caucasians. Am J Epidemiol 133:801–809PubMed
16.
Zurück zum Zitat Xiong DH, Liu YZ, Liu PY, Zhao LJ, Deng HW (2005) Association analysis of estrogen receptor alpha gene polymorphisms with cross-sectional geometry of the femoral neck in Caucasian nuclear families. Osteoporos Int 16:2113–2122CrossRefPubMed Xiong DH, Liu YZ, Liu PY, Zhao LJ, Deng HW (2005) Association analysis of estrogen receptor alpha gene polymorphisms with cross-sectional geometry of the femoral neck in Caucasian nuclear families. Osteoporos Int 16:2113–2122CrossRefPubMed
17.
Zurück zum Zitat Deng FY, Xiao P, Lei SF, Zhang L, Yang F, Tang ZH, Liu PY, Liu YJ, Recker RR, Deng HW (2007) Bivariate whole genome linkage analysis for femoral neck geometric parameters and total body lean mass. J Bone Miner Res 22:808–816CrossRefPubMed Deng FY, Xiao P, Lei SF, Zhang L, Yang F, Tang ZH, Liu PY, Liu YJ, Recker RR, Deng HW (2007) Bivariate whole genome linkage analysis for femoral neck geometric parameters and total body lean mass. J Bone Miner Res 22:808–816CrossRefPubMed
18.
Zurück zum Zitat Deng HW, Deng H, Liu YJ, Liu YZ, Xu FH, Shen H, Conway T, Li JL, Huang QY, Davies KM, Recker RR (2002) A genomewide linkage scan for quantitative-trait loci for obesity phenotypes. Am J Hum Genet 70:1138–1151CrossRefPubMed Deng HW, Deng H, Liu YJ, Liu YZ, Xu FH, Shen H, Conway T, Li JL, Huang QY, Davies KM, Recker RR (2002) A genomewide linkage scan for quantitative-trait loci for obesity phenotypes. Am J Hum Genet 70:1138–1151CrossRefPubMed
19.
Zurück zum Zitat Deng HW, Deng XT, Conway T, Xu FH, Heaney R, Recker RR (2002) Determination of bone size of hip, spine, and wrist in human pedigrees by genetic and lifestyle factors. J Clin Densitom 5:45–56CrossRefPubMed Deng HW, Deng XT, Conway T, Xu FH, Heaney R, Recker RR (2002) Determination of bone size of hip, spine, and wrist in human pedigrees by genetic and lifestyle factors. J Clin Densitom 5:45–56CrossRefPubMed
20.
Zurück zum Zitat Recker R, Lappe J, Davies K, Heaney R (2000) Characterization of perimenopausal bone loss: a prospective study. J Bone Miner Res 15(10):1965–1973CrossRefPubMed Recker R, Lappe J, Davies K, Heaney R (2000) Characterization of perimenopausal bone loss: a prospective study. J Bone Miner Res 15(10):1965–1973CrossRefPubMed
21.
Zurück zum Zitat Deng HW, Chen WM, Conway T, Zhou Y, Davies KM, Stegman MR, Deng H, Recker RR (2000) Determination of bone mineral density of the hip and spine in human pedigrees by genetic and life-style factors. Genet Epidemiol 19(2):160–177CrossRefPubMed Deng HW, Chen WM, Conway T, Zhou Y, Davies KM, Stegman MR, Deng H, Recker RR (2000) Determination of bone mineral density of the hip and spine in human pedigrees by genetic and life-style factors. Genet Epidemiol 19(2):160–177CrossRefPubMed
22.
Zurück zum Zitat Filardi S, Zebaze RM, Duan Y, Edmonds J, Beck T, Seeman E (2004) Femoral neck fragility in women has its structural and biomechanical basis established by periosteal modeling during growth and endocortical remodeling during aging. Osteoporos Int 15:103–107CrossRefPubMed Filardi S, Zebaze RM, Duan Y, Edmonds J, Beck T, Seeman E (2004) Femoral neck fragility in women has its structural and biomechanical basis established by periosteal modeling during growth and endocortical remodeling during aging. Osteoporos Int 15:103–107CrossRefPubMed
23.
Zurück zum Zitat Kaptoge S, Dalzell N, Loveridge N, Beck TJ, Khaw KT, Reeve J (2003) Effects of gender, anthropometric variables, and aging on the evolution of hip strength in men and women aged over 65. Bone 32:561–570CrossRefPubMed Kaptoge S, Dalzell N, Loveridge N, Beck TJ, Khaw KT, Reeve J (2003) Effects of gender, anthropometric variables, and aging on the evolution of hip strength in men and women aged over 65. Bone 32:561–570CrossRefPubMed
24.
Zurück zum Zitat Rivadeneira F, Houwing-Duistermaat JJ, Beck TJ, Janssen JA, Hofman A, Pols HA, Van Duijn CM, Uitterlinden AG (2004) The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: the Rotterdam Study. J Bone Miner Res 19:1280–1290CrossRefPubMed Rivadeneira F, Houwing-Duistermaat JJ, Beck TJ, Janssen JA, Hofman A, Pols HA, Van Duijn CM, Uitterlinden AG (2004) The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: the Rotterdam Study. J Bone Miner Res 19:1280–1290CrossRefPubMed
25.
Zurück zum Zitat Duan Y, Beck TJ, Wang XF, Seeman E (2003) Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging. J Bone Miner Res 18:1766–1774CrossRefPubMed Duan Y, Beck TJ, Wang XF, Seeman E (2003) Structural and biomechanical basis of sexual dimorphism in femoral neck fragility has its origins in growth and aging. J Bone Miner Res 18:1766–1774CrossRefPubMed
26.
Zurück zum Zitat Beck TJ, Looker AC, Ruff CB, Sievanen H, Wahner HW (2000) Structural trends in the aging femoral neck and proximal shaft: analysis of the Third National Health and Nutrition Examination Survey dual-energy X-ray absorptiometry data. J Bone Miner Res 15:2297–2304CrossRefPubMed Beck TJ, Looker AC, Ruff CB, Sievanen H, Wahner HW (2000) Structural trends in the aging femoral neck and proximal shaft: analysis of the Third National Health and Nutrition Examination Survey dual-energy X-ray absorptiometry data. J Bone Miner Res 15:2297–2304CrossRefPubMed
27.
Zurück zum Zitat Lauderdale DS, Jacobsen SJ, Furner SE, Levy PS, Brody JA, Goldberg J (1997) Hip fracture incidence among elderly Asian-American populations. Am J Epidemiol 146:502–509PubMed Lauderdale DS, Jacobsen SJ, Furner SE, Levy PS, Brody JA, Goldberg J (1997) Hip fracture incidence among elderly Asian-American populations. Am J Epidemiol 146:502–509PubMed
28.
Zurück zum Zitat Nakamura T, Turner CH, Yoshikawa T, Slemenda CW, Peacock M, Burr DB, Mizuno Y, Orimo H, Ouchi Y, Johnston CC Jr (1994) Do variations in hip geometry explain differences in hip fracture risk between Japanese and white Americans? J Bone Miner Res 9:1071–1076CrossRefPubMed Nakamura T, Turner CH, Yoshikawa T, Slemenda CW, Peacock M, Burr DB, Mizuno Y, Orimo H, Ouchi Y, Johnston CC Jr (1994) Do variations in hip geometry explain differences in hip fracture risk between Japanese and white Americans? J Bone Miner Res 9:1071–1076CrossRefPubMed
29.
Zurück zum Zitat Lekamwasam S, Lenora J (2007) Age-related trends in hip geometry in Sri Lankan women: a cross-sectional study. J Bone Miner Metab 25:431–435CrossRefPubMed Lekamwasam S, Lenora J (2007) Age-related trends in hip geometry in Sri Lankan women: a cross-sectional study. J Bone Miner Metab 25:431–435CrossRefPubMed
30.
Zurück zum Zitat Yu W, Qin M, Xu L, van Kuijk C, Meng X, Xing X, Cao J, Genant HK (1999) Normal changes in spinal bone mineral density in a Chinese population: assessment by quantitative computed tomography and dual-energy X-ray absorptiometry. Osteoporos Int 9:179–187CrossRefPubMed Yu W, Qin M, Xu L, van Kuijk C, Meng X, Xing X, Cao J, Genant HK (1999) Normal changes in spinal bone mineral density in a Chinese population: assessment by quantitative computed tomography and dual-energy X-ray absorptiometry. Osteoporos Int 9:179–187CrossRefPubMed
31.
Zurück zum Zitat Fujii Y, Tsutsumi M, Tsunenari T, Fukase M, Yoshimoto Y, Fujita T, Genant HK (1989) Quantitative computed tomography of lumbar vertebrae in Japanese patients with osteoporosis. Bone Miner 6:87–94CrossRefPubMed Fujii Y, Tsutsumi M, Tsunenari T, Fukase M, Yoshimoto Y, Fujita T, Genant HK (1989) Quantitative computed tomography of lumbar vertebrae in Japanese patients with osteoporosis. Bone Miner 6:87–94CrossRefPubMed
32.
Zurück zum Zitat Beck TJ, Oreskovic TL, Stone KL, Ruff CB, Ensrud K, Nevitt MC, Genant HK, Cummings SR (2001) Structural adaptation to changing skeletal load in the progression toward hip fragility: the study of osteoporotic fractures. J Bone Miner Res 16:1108–1119CrossRefPubMed Beck TJ, Oreskovic TL, Stone KL, Ruff CB, Ensrud K, Nevitt MC, Genant HK, Cummings SR (2001) Structural adaptation to changing skeletal load in the progression toward hip fragility: the study of osteoporotic fractures. J Bone Miner Res 16:1108–1119CrossRefPubMed
33.
Zurück zum Zitat Yoshimura N, Hashimoto T, Sakata K, Morioka S, Kasamatsu T, Cooper C (1999) Biochemical markers of bone turnover and bone loss at the lumbar spine and femoral neck: the Taiji study. Calcif Tissue Int 65:198–202CrossRefPubMed Yoshimura N, Hashimoto T, Sakata K, Morioka S, Kasamatsu T, Cooper C (1999) Biochemical markers of bone turnover and bone loss at the lumbar spine and femoral neck: the Taiji study. Calcif Tissue Int 65:198–202CrossRefPubMed
34.
Zurück zum Zitat Sone T, Miyake M, Takeda N, Fukunaga M (1995) Urinary excretion of type I collagen crosslinked N-telopeptides in healthy Japanese adults: age- and sex-related changes and reference limits. Bone 17:335–339CrossRefPubMed Sone T, Miyake M, Takeda N, Fukunaga M (1995) Urinary excretion of type I collagen crosslinked N-telopeptides in healthy Japanese adults: age- and sex-related changes and reference limits. Bone 17:335–339CrossRefPubMed
35.
Zurück zum Zitat Tsai KS, Pan WH, Hsu SH, Cheng WC, Chen CK, Chieng PU, Yang RS, Twu ST (1996) Sexual differences in bone markers and bone mineral density of normal Chinese. Calcif Tissue Int 59:454–460PubMed Tsai KS, Pan WH, Hsu SH, Cheng WC, Chen CK, Chieng PU, Yang RS, Twu ST (1996) Sexual differences in bone markers and bone mineral density of normal Chinese. Calcif Tissue Int 59:454–460PubMed
36.
Zurück zum Zitat Center JR, Nguyen TV, Sambrook PN, Eisman JA (1999) Hormonal and biochemical parameters in the determination of osteoporosis in elderly men. J Clin Endocrinol Metab 84:3626–3635CrossRefPubMed Center JR, Nguyen TV, Sambrook PN, Eisman JA (1999) Hormonal and biochemical parameters in the determination of osteoporosis in elderly men. J Clin Endocrinol Metab 84:3626–3635CrossRefPubMed
37.
Zurück zum Zitat Greendale GA, Edelstein S, Barrett-Connor E (1997) Endogenous sex steroids and bone mineral density in older women and men: the Rancho Bernardo Study. J Bone Miner Res 12:1833–1843CrossRefPubMed Greendale GA, Edelstein S, Barrett-Connor E (1997) Endogenous sex steroids and bone mineral density in older women and men: the Rancho Bernardo Study. J Bone Miner Res 12:1833–1843CrossRefPubMed
38.
Zurück zum Zitat Hughes DE, Dai A, Tiffee JC, Li HH, Mundy GR, Boyce BF (1996) Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta. Nat Med 2:1132–1136CrossRefPubMed Hughes DE, Dai A, Tiffee JC, Li HH, Mundy GR, Boyce BF (1996) Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta. Nat Med 2:1132–1136CrossRefPubMed
39.
Zurück zum Zitat Gilbert L, He X, Farmer P, Boden S, Kozlowski M, Rubin J, Nanes MS (2000) Inhibition of osteoblast differentiation by tumor necrosis factor-alpha. Endocrinology 141:3956–3964CrossRefPubMed Gilbert L, He X, Farmer P, Boden S, Kozlowski M, Rubin J, Nanes MS (2000) Inhibition of osteoblast differentiation by tumor necrosis factor-alpha. Endocrinology 141:3956–3964CrossRefPubMed
40.
Zurück zum Zitat Meunier PJ, Chapuy MC, Arlot ME, Delmas PD, Duboeuf F (1994) Can we stop bone loss and prevent hip fractures in the elderly? Osteoporos Int 4(Suppl 1):71–76CrossRefPubMed Meunier PJ, Chapuy MC, Arlot ME, Delmas PD, Duboeuf F (1994) Can we stop bone loss and prevent hip fractures in the elderly? Osteoporos Int 4(Suppl 1):71–76CrossRefPubMed
41.
Zurück zum Zitat Eriksen EF, Langdahl B, Vesterby A, Rungby J, Kassem M (1999) Hormone replacement therapy prevents osteoclastic hyperactivity: a histomorphometric study in early postmenopausal women. J Bone Miner Res 14:1217–1221CrossRefPubMed Eriksen EF, Langdahl B, Vesterby A, Rungby J, Kassem M (1999) Hormone replacement therapy prevents osteoclastic hyperactivity: a histomorphometric study in early postmenopausal women. J Bone Miner Res 14:1217–1221CrossRefPubMed
42.
Zurück zum Zitat Pacifici R (2007) Estrogen deficiency, T cells and bone loss. Cell Immunol 252(1–2):68–80PubMed Pacifici R (2007) Estrogen deficiency, T cells and bone loss. Cell Immunol 252(1–2):68–80PubMed
43.
Zurück zum Zitat O'Neill TW, Felsenberg D, Varlow J, Cooper C, Kanis JA, Silman AJ (1996) The prevalence of vertebral deformity in european men and women: the European Vertebral Osteoporosis Study. J Bone Miner Res 11:1010–1018CrossRefPubMed O'Neill TW, Felsenberg D, Varlow J, Cooper C, Kanis JA, Silman AJ (1996) The prevalence of vertebral deformity in european men and women: the European Vertebral Osteoporosis Study. J Bone Miner Res 11:1010–1018CrossRefPubMed
44.
Zurück zum Zitat Ebbesen EN, Thomsen JS, Beck-Nielsen H, Nepper-Rasmussen HJ, Mosekilde L (1999) Age- and gender-related differences in vertebral bone mass, density, and strength. J Bone Miner Res 14:1394–1403CrossRefPubMed Ebbesen EN, Thomsen JS, Beck-Nielsen H, Nepper-Rasmussen HJ, Mosekilde L (1999) Age- and gender-related differences in vertebral bone mass, density, and strength. J Bone Miner Res 14:1394–1403CrossRefPubMed
45.
Zurück zum Zitat Duan Y, Seeman E (2002) Bone fragility in Asian and Caucasian men. Ann Acad Med Singap 31:54–66PubMed Duan Y, Seeman E (2002) Bone fragility in Asian and Caucasian men. Ann Acad Med Singap 31:54–66PubMed
46.
Zurück zum Zitat Liao EY, Wu XP, Deng XG, Huang G, Zhu XP, Long ZF, Wang WB, Tang WL, Zhang H (2002) Age-related bone mineral density, accumulated bone loss rate and prevalence of osteoporosis at multiple skeletal sites in chinese women. Osteoporos Int 13:669–676CrossRefPubMed Liao EY, Wu XP, Deng XG, Huang G, Zhu XP, Long ZF, Wang WB, Tang WL, Zhang H (2002) Age-related bone mineral density, accumulated bone loss rate and prevalence of osteoporosis at multiple skeletal sites in chinese women. Osteoporos Int 13:669–676CrossRefPubMed
47.
Zurück zum Zitat Seeman E (2003) The structural and biomechanical basis of the gain and loss of bone strength in women and men. Endocrinol Metab Clin North Am 32:25–38CrossRefPubMed Seeman E (2003) The structural and biomechanical basis of the gain and loss of bone strength in women and men. Endocrinol Metab Clin North Am 32:25–38CrossRefPubMed
48.
Zurück zum Zitat Lips P, Courpron P, Meunier PJ (1978) Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age. Calcif Tissue Res 26:13–17CrossRefPubMed Lips P, Courpron P, Meunier PJ (1978) Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age. Calcif Tissue Res 26:13–17CrossRefPubMed
Metadaten
Titel
The differences of femoral neck geometric parameters: effects of age, gender and race
verfasst von
F. Zhang
L.-J. Tan
S.-F. Lei
H.-W. Deng
Publikationsdatum
01.07.2010
Verlag
Springer-Verlag
Erschienen in
Osteoporosis International / Ausgabe 7/2010
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-009-1057-0

Weitere Artikel der Ausgabe 7/2010

Osteoporosis International 7/2010 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.