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Social Psychiatry and Psychiatric Epidemiology

Erschienen in:

01.06.2015 | Invited Reviews

The ‘Early Developmental Stages of Psychopathology (EDSP) study’: a 20-year review of methods and findings

verfasst von: Katja Beesdo-Baum, Susanne Knappe, Eva Asselmann, Petra Zimmermann, Tanja Brückl, Michael Höfler, Silke Behrendt, Roselind Lieb, Hans-Ulrich Wittchen

Erschienen in: Social Psychiatry and Psychiatric Epidemiology | Ausgabe 6/2015

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Abstract

Purpose

The “Early Developmental Stages of Psychopathology (EDSP)” study is a prospective-longitudinal study program in a community sample (Munich, Germany) of adolescents and young adults. The program was launched in 1994 to study the prevalence and incidence of psychopathological syndromes and mental disorders, to describe the natural course and to identify vulnerability and risk factors for onset and progression as well as psychosocial consequences. This paper reviews methods and core outcomes of this study program.

Methods

The EDSP is based on an age-stratified random community sample of originally N = 3021 subjects aged 14–24 years at baseline, followed up over 10 years with up to 3 follow-up waves. The program includes a family genetic supplement and nested cohorts with lab assessments including blood samples for genetic analyses. Psychopathology was assessed with the DSM-IV/M-CIDI; embedded dimensional scales and instruments assessed vulnerability and risk factors.

Results

Beyond the provision of age-specific prevalence and incidence rates for a wide range of mental disorders, analyses of their patterns of onset, course and interrelationships, the program identified common and diagnosis-specific distal and proximal vulnerability and risk factors including critical interactions.

Conclusions

The EDSP study advanced our knowledge on the developmental pathways and trajectories, symptom progression and unfolding of disorder comorbidity, highlighting the dynamic nature of many disorders and their determinants. The results have been instrumental for defining more appropriate diagnostic thresholds, led to the derivation of symptom progression models and were helpful to identify promising targets for prevention and intervention.

Nur mit Berechtigung zugänglich

Previous publications include assessments up to T2. Completed information on assessments up to T3 is available from the corresponding author upon request.

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Titel: The ‘Early Developmental Stages of Psychopathology (EDSP) study’: a 20-year review of methods and findings
verfasst von: Katja Beesdo-Baum
Susanne Knappe
Eva Asselmann
Petra Zimmermann
Tanja Brückl
Michael Höfler
Silke Behrendt
Roselind Lieb
Hans-Ulrich Wittchen
Publikationsdatum: 01.06.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: Social Psychiatry and Psychiatric Epidemiology / Ausgabe 6/2015
Print ISSN: 0933-7954
Elektronische ISSN: 1433-9285
DOI: https://doi.org/10.1007/s00127-015-1062-x

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The ‘Early Developmental Stages of Psychopathology (EDSP) study’: a 20-year review of methods and findings

Abstract

Purpose

Methods

Results

Conclusions

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Springer Medizin

Abstract

Purpose

Methods

Results

Conclusions

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