Acknowledgements cohorts
We are grateful to all families and participants who took part in these studies. We also acknowledge and appreciate the unique efforts of the research teams and practitioners contributing to the collection of this wealth of data. C.M.M. is supported by funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement no. 721567. J.F.F. has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 633595 (DynaHEALTH) and 733206 (LifeCycle). R.M.F. and R.N.B. are supported by Sir Henry Dale Fellowship (Wellcome Trust and Royal Society grant: WT104150). D.L.C. is funded by the American Diabetes Association Grant 1-17-PDF-077. D.O.M-K. was supported by Dutch Science Organization (ZonMW-VENI Grant 916.14.023). N.M.W. is supported by an Australian National Health and Medical Research Council Early Career Fellowship (APP1104818). T.S.A. was partially funded by the Gene-Diet Interactions in Obesity (GENDINOB) project on behalf of GOYA male cohort data management and analyses and acknowledges the same. S.D. was supported by National Institute of Health Research. T.M.F. is supported by the European Research Council grant: 323195 SZ-245 50371-GLUCOSEGENES-FP7-IDEAS-ERC. The Novo Nordisk Foundation Center for Basic Metabolic Research is an independent Research Center at the University of Copenhagen partially funded by an unrestricted donation from the Novo Nordisk Foundation (
www.metabol.ku.dk). H.H. is funded by The Children’s Hospital of Philadelphia Endowed Chair in Genomic Research. A.T.H. is supported by the Wellcome Trust Senior Investigator Awards (WT098395), National Institute for Health Research (NIHR) Senior Investigator Award (NF-SI-0611-10219). J.Hebebrand received grants from German Research Society, German Ministry of Education and Research. M-F.H. is currently supported by an American Diabetes Association (ADA) Pathway Program Accelerator Early Investigator Award (1-15-ACE-26). S.J. is supported by Helse Vest no. 23929, Bergen Forskningsstiftelse and KG Jebsen Foundation and University of Bergen. J.K. has been supported by the Academy of Finland Research Professor program (grants 265240 & 263278). J.P.K. is funded by a University of Queensland Development Fellowship (UQFEL1718945). H.L. has served as a speaker for Eli-Lilly and Shire and has received research grants from Shire; all outside the submitted work. C.M.L is supported by the Li Ka Shing Foundation, WT-SSI/John Fell funds and by the NIHR Biomedical Research Centre, Oxford, by Widenlife and NIH (5P50HD028138-27). S.E.M. was funded by an NHMRC Senior Reseach Fellowship (APP1103623). K.Panoutsopoulou is funded by a career development fellowship (grant 20308) and by the Wellcome Trust (WT098051). C.P. at UCL Institute of Child Health, with support from the National Institute for Health Research Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Foundation Trust and University College London. I.P. was funded in part by the Wellcome Trust (WT205915), and the European Union’s Horizon 2020 research, the European Union FP7-IDEAS-ERC Advanced Grant (GEPIDIAB, ERC-AG – ERC- 294785), and innovation programme (DYNAhealth, H2020-PHC-2014-633595). R.C.R. is supported by CRUK (grant number C18281/A19169). J.G.S. is supported by an NHMRC Practitioner Fellowship Grant (APP1105807). J.T. is funded by the European Regional Development Fund (ERDF), the European Social Fund (ESF), Convergence Programme for Cornwall and the Isles of Scilly and the Diabetes Research and Wellness Foundation Non-Clinical Fellowship. N.V-T. is funded by a pre-doctoral grant from the Agència de Gestió d’Ajuts Universitaris i de Recerca (AGAUR) (2015 FI_B 00636), Generalitat de Catalunya. T.G.M.V was supported by ZonMW (TOP 40–00812–98–11010. J.F.W. is supported by the MRC Human Genetics Unit quinquennial programme “QTL in Health andDisease”. H.Y. is funded by Diabetes UK RD Lawrence fellowship (grant: 17/0005594). M.H.Z was supported by BBMRI-NL (CP2013-50). E.Z. is supported by the Wellcome Trust (098051). B.F. is supported by Novo Nordisk Foundation (12955) and an Oak Foundation Fellowship. S.S. and M-R.J. have received funding from the European Union’s Horizon 2020 research and innovation programme [under grant agreement No 633595] for the DynaHEALTH action. P.R.N. was supported by the European Research Council (ERC), University of Bergen, KG Jebsen and Helse Vest. G.D.S. works within the MRC Integrative Epidemiology Unit at the University of Bristol (MC_UU_12013/1). D.A.L was supported by the European Research Council under the European Union's Seventh Framework Programme (FP/2007-2013) / ERC Grant Agreement (Grant number 669545; DevelopObese), US National Institute of Health (grant: R01 DK10324), the UK Medical Research Council (grant: MC_UU_00011/6), Wellcome Trust GWAS grant (WT088806), an NIHR Senior Investigator Award (NF-SI-0611-10196) and the NIHR Biomedical Research Centre at University Hospitals Bristol NHS Foundation Trust and the University of Bristol. L.Paternoster was supported by the UK Medical Research Council Unit grants MC_UU_12013_5. N.J.T. is a Wellcome Trust Investigator (202802/Z/16/Z), is the PI of the Avon Longitudinal Study of Parents and Children (MRC & WT 102215/2/13/2), is supported by the University of Bristol NIHR Biomedical Research Centre (BRC) and works within the CRUK Integrative Cancer Epidemiology Programme (C18281/A19169). V.W.V.J. received an additional grant from the Netherlands Organization for Health Research and Development (NWO, ZonMw-VIDI 016.136.361), a European Research Council Consolidator Grant (ERC-2014-CoG-648916) and funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 633595 (DynaHEALTH) and 733206 (LifeCycle). D.M.E. is funded by the UK Medical Research Council Unit grant MC_UU_12013_4, Australian Research Council Future Fellowship (FT130101709) and a NHMRC Senior Research Fellowship (GNT1137714). S.F.A.G. is funded by the Daniel B. Burke Endowed Chair for Diabetes Research and R01 HD056465. D.I.B. is supported by Spinozapremie (NWO-56-464-14192) and the Royal Netherlands Academy of Science Professor Award (PAH/6635) to DIB. M.I.M. is a Wellcome Senior Investgator and NIHR Senior Investigator supported by the Wellcome (090532, 098381, 203141), NIHR (NF-SI-0617-10090) and the NIHR Biomedical Research Centre, Oxford. The views expressed in this article are those of the author(s) and not necessarily those of the NHS, the NIHR, or the Department of Health.
INMA
This study was funded by grants from Instituto de Salud Carlos III (Red INMA G03/176; CB06/02/0041; PI041436; PI081151 incl. FEDER funds; PI12/01890 incl. FEDER funds; CP13/00054 incl. FEDER funds, FIS-FEDER: PI03/1615, PI04/1509, PI04/1112, PI04/1931, PI05/1079, PI05/1052, PI06/1213, PI07/0314, PI09/02647, PI11/01007, PI11/02591, PI11/02038, PI13/1944, PI13/2032, PI14/00891, PI14/01687, and PI16/1288; Miguel Servet-FEDER CP11/00178, CP15/00025, CPII16/00051, FIS-PI06/0867, FIS-PI09/00090, FIS-PI13/02187, 97/0588; 00/0021-2; PI061756; PS0901958; PI14/00677 incl. FEDER funds), CIBERESP, Generalitat de Catalunya-CIRIT 1999SGR 00241, Generalitat de Catalunya-AGAUR (2009 SGR 501, 2014 SGR 822), Fundació La marató de TV3 (090430), Spanish Ministry of Economy and Competitiveness (SAF2012-32991 incl. FEDER funds), Agence Nationale de Securite Sanitaire de l’Alimentation de l’Environnement et du Travail (1262C0010), EU Commission (261357, 308333, 603794, 634453, FP7-ENV-2011 cod 282957 and HEALTH.2010.2.4.5-1), Beca de la IV convocatoria de Ayudas a la Investigación en Enfermedades Neurodegenerativas de La Caixa, EC Contract No. QLK4-CT-2000-00263, Generalitat Valenciana: FISABIO (UGP 15-230, UGP-15-244, and UGP-15-249), Department of Health of the Basque Government (2005111093, 2009111069, 2013111089 and 2015111065), and the Provincial Government of Gipuzkoa (DFG06/002, DFG08/001 and DFG15/221) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu , Legazpi, Azkoitia y Azpeitia y Beasain). ISGlobal is a member of the CERCA Programme, Generalitat de Catalunya.
The authors for this manuscript are:
Christel M Middeldorp1,2,3, Janine F Felix4,5,6, Anubha Mahajan7,8, Momoko Horikoshi7,8,9, Neil R Robertson7,8, Robin N Beaumont10, Jonathan P Bradfield11,12, Mariona Bustamante13,14,15, Diana L Cousminer16,17, Felix R Day18, N Maneka De Silva19, Monica Guxens13,14,15, Dennis O Mook-Kanamori20,21, Beate St Pourcain22,23, Nicole M Warrington24, Linda S Adair25, Emma Ahlqvist26, Tarunveer S Ahluwalia27,28,29, Peter Almgren26, Wei Ang30, Mustafa Atalay31, Juha Auvinen32, Meike Bartels3,33,34, Jacques S Beckmann35, Jose Ramon Bilbao36,37,38, Tom Bond19, Judith B Borja39,40, Alana Cavadino41,42, Pimphen Charoen19,43, Zhanghua Chen44, Lachlan Coin45, Cyrus Cooper46, John A Curtin47, Adnan Custovic48, Shikta Das42, Gareth E Davies49, George V Dedoussis50, Liesbeth Duijts4,51,52, Peter R Eastwood53,54, Anders U Eliasen55,56, Paul Elliott19, Johan G Eriksson57,58,59, Xavier Estivill60, João Fadista61, Iryna O Fedko3,33, Timothy M Frayling10, Romy Gaillard5, W James Gauderman44, Frank Geller61, Frank Gilliland44, Vincente Gilsanz62, Raquel Granell63, Niels Grarup28, Leif Groop26,64, Dexter Hadley65, Hakon Hakonarson11,16,66, Torben Hansen28, Catharina A Hartman67, Andrew T Hattersley10,68, M Geoffrey Hayes69, Johannes Hebebrand70, Joachim Heinrich71,72, Øyvind Helgeland73,74,75, Anjali K Henders45, John Henderson63, Tine B Henriksen76, Joel N Hirschhorn77,78,79, Marie-France Hivert80,81,82, Berthold Hocher83,84, John W Holloway85, Patrick Holt86, Jouke-Jan Hottenga3,33,34, Elina Hyppönen42,87,88, Carmen Iñíguez15,89,90, Stefan Johansson73,91, Astanand Jugessur92,93,94, Mika Kähönen95,96, Heidi J Kalkwarf97, Jaakko Kaprio64,98, Ville Karhunen99, John P Kemp23,24,63, Marjan Kerkhof100, Gerard H Koppelman101, Antje Körner102,103, Sailesh Kotecha104, Eskil Kreiner-Møller27,105, Benard Kulohoma7, Ashish Kumar106,107, Zoltán Kutalik108,109, Jari Lahti110,111, Joan M Lappe112, Henrik Larsson113,114, Terho Lehtimäki115,116, Alexandra M Lewin19, Jin Li11, Paul Lichtenstein114, Cecilia M Lindgren7,117,118, Virpi Lindi31, Allan Linneberg119,120, Xueping Liu61, Jun Liu5, William L Lowe Jr69, Sebastian Lundström121,122, Leo-Pekka Lyytikäinen115,116, Ronald CW Ma123,124,125, Aurélien Macé108, Reedik Mägi126, Per Magnus93, Abdullah A Mamun127, Minna Mannikko32, Nicholas G Martin128, Hamdi Mbarek3,33,34,129, Nina S McCarthy130, Sarah E Medland128, Mads Melbye61,131, Erik Melén106,132, Karen L Mohlke133, Claire Monnereau4,5,6, Camilla S Morgen134, Andrew P Morris7,126,135, Jeffrey C Murray136, Ronny Myhre92, Jackob M Najman137, Michel G Nivard3,33, Ellen A Nohr138, Ilja M Nolte139, Ioanna Ntalla140, Paul O’Reilly141, Sharon E Oberfield142, Emily Oken143, Albertine J Oldehinkel67, Katja Pahkala144,145, Teemu Palviainen64, Kalliope Panoutsopoulou146, Oluf Pedersen28, Craig E Pennell147, Göran Pershagen106,148, Niina Pitkänen144, Robert Plomin149, Christine Power42, Rashmi B Prasad26, Inga Prokopenko7,150, Lea Pulkkinen151, Katri Räikkönen111, Olli T Raitakari144,152, Rebecca M Reynolds153, Rebecca C Richmond23,63, Fernando Rivadeneira4,5,154, Alina Rodriguez19,155, Richard J Rose156, Rany Salem78,157,158,159, Loreto Santa-Marina15,160,161, Seang-Mei Saw162,163, Theresia M Schnurr28, James G Scott137,164,165, Saskia Selzam149, John A Shepherd166, Angela Simpson47, Line Skotte61, Patrick MA Sleiman11,66, Harold Snieder139, Thorkild IA Sørensen23,28,134, Marie Standl71, Eric AP Steegers167, David P Strachan168, Leon Straker169, Timo Strandberg32,170,171, Michelle Taylor23,63, Yik-Ying Teo162,172,173, Elisabeth Thiering71,174, Maties Torrent15,175,176, Jessica Tyrrell10,177, André G Uitterlinden4,5,154, Toos van Beijsterveldt3,33, Peter J van der Most139, Cornelia M van Duijn5, Jorma Viikari178,179, Natalia Vilor-Tejedor180,181, Suzanne Vogelezang4,5,6, Judith M Vonk139,182, Tanja GM Vrijkotte183, Eero Vuoksimaa64, Carol A Wang147, William J Watkins104, H-Erich Wichmann71,184,185, Gonneke Willemsen3,33,34, Gail M Williams137, James F Wilson186,187, Naomi R Wray45,188, Shujing Xu44, Cheng-Jian Xu101, Hanieh Yaghootkar189, Lu Yi114, Mohammad Hadi Zafarmand183,190, Eleftheria Zeggini146, Babette S Zemel191, Anke Hinney70, Timo A Lakka31,192,193, Andrew JO Whitehouse86, Jordi Sunyer13,14,15,194, Elisabeth E Widén64, Bjarke Feenstra61, Sylvain Sebert19,32,195,196, Bo Jacobsson75,197, Pål R Njølstad73,74, Camilla Stoltenberg198, George Davey Smith23,63, Debbie A Lawlor23,63,199, Lavinia Paternoster23,63, Nicholas J Timpson23,63, Ken K Ong18,200, Hans
Bisgaard27, Klaus Bønnelykke27, Vincent WV Jaddoe4,5,6, Henning Tiemeier201,202, Marjo-Riitta Järvelin19,32,195,203,204, David M Evans23,24,63, John RB Perry18, Struan FA Grant11,16,17,66, Dorret I Boomsma3,33,34,129, Rachel M Freathy10,23, Mark I McCarthy7,8,205
1. Child Health Research Centre, University of Queensland, Brisbane, QLD, Australia. 2. Child and Youth Mental Health Service, Children’s Health Queensland Hospital and Health Service, Brisbane, QLD, Australia. 3. Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, 1081 BT, The Netherlands. 4. The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 5. Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 6. Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 7. Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK. 8. Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, OX3 7LE, UK. 9. RIKEN, Centre for Integrative Medical Sciences, Laboratory for Endocrinology, Metabolism and Kidney diseases, Yokohama, Kanagawa, 230-0045, Japan. 10. Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, EX2 5DW, UK. 11. Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA. 12. Quantinuum Research LLC, San Diego, CA, 92101, USA. 13. ISGlobal, Institute for Global Health, Barcelona, 08003, Spain. 14. Universitat Pompeu Fabra (UPF), Barcelona, 08003, Spain. 15. CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, 28029, Spain. 16. Division of Human Genetics, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA. 17. Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104, USA. 18. MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK. 19. Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, W2 1PG, UK. 20. Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands. 21. Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands. 22. Max Planck Institute for Psycholinguistics, Nijmegen, 6525 XD, The Netherlands. 23. Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, BS8 2BN, UK. 24. University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD, 4072, Australia. 25. Department of Nutrition, University of North Carolina, Chapel Hill, NC 27599, USA. 26. Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, SE-205 02, Sweden. 27. 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Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany. 72. Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital of Ludwig Maximilians University, Munich, Germany. 73. KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, N-5020, Norway. 74. Department of Pediatrics, Haukeland University Hospital, Bergen, 5021, Norway. 75. Department of Genetics and Bioinformatics, Domain of Health Data and Digitalisation, Norwegian Institute of Public Health, Oslo, N-0473, Norway. 76. Department of Paediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus N, DK-8200, Denmark. 77. Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. 78. Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. 79. 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Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA. 134. Department of Public Health, Section of Epidemiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Copenhagen, DK-1014, Denmark. 135. Department of Biostatistics, University of Liverpool, Liverpool, L69 3GL, UK. 136. Department of Pediatrics, University of Iowa, Iowa City, IA 52242, USA. 137. School of Public Health, The University of Queensland, QLD, Australia. 138. Research Unit for Gynaecology and Obstetrics, Institute of Clinical Research, University of Southern Denmark, Odense, DK-5000, Denmark. 139. Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. 140. William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK. 141. Medical Research Council (MRC), Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, SE5 8AF, UK. 142. Division of Pediatric Endocrinology, Diabetes, and Metabolism, Department of Pediatrics, Columbia University Medical Center, New York, NY 10032, USA. 143. Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA. 144. Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20014, Finland. 145. Paavo Nurmi Centre, Sports and Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland. 146. Wellcome Sanger Institute, Hinxton, Cambridgeshire, CB10 1HH, UK. 147. School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle, Callaghan, NSW, 2308, Australia. 148. Centre for Occupational and Environmental Medicine, Stockholm County Council, Sweden. 149. MRC Social, Genetic and Developmental Psychiatry Centre, King’s College London, London, UK. 150. Section of Genomics of Common Disease, Department of Medicine, Imperial College London, London, SW7 2AZ, UK. 151. Department of Psychology, University of Jyväskylä, Jyväskylä, Finland. 152. Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, 20520, Finland. 153. BHF Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, Edinburgh, EH16 4TJ, UK. 154. Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 155. Department of Psychology, Mid Sweden University, Östersund, SE-831 25, Sweden. 156. Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana, USA. 157. Department of Medicine, Division of Endocrinology, Boston Children’s Hospital, Boston, MA 02115, USA. 158. Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. 159. Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, MA 02115, USA. 160. Subdirección de Salud Pública y Adicciones de Gipuzkoa, San Sebastián, Spain. 161. Instituto de Investigación Sanitaria Biodonostia, San Sebastián, Spain. 162. Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, 119077, Singapore. 163. Singapore Eye Research Institute, Singapore, 168751, Singapore. 164. Metro North Mental Health Service, QLD, Australia. 165. Queensland Centre for Mental Health Research, QLD, Australia. 166. Department of Epidemiology, Cancer Center, University of Hawaii (Manoa), Honolulu, Hawaii, 96813, USA. 167. Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 168. Population Health Research Institute, St George’s University of London, London, SW17 0RE, UK. 169. School of Physiotherapy and Exercise Science, Faculty of Health Sciences, Curtin University, Perth, WA, Australia. 170. Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland. 171. Clinicum, University of Helsinki, Helsinki, Finland. 172. Department of Statistics and Applied Probability, National University of Singapore, Singapore, 117546, Singapore. 173. Life Sciences Institute, National University of Singapore, Singapore, 117456, Singapore. 174. Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children’s Hospital, University of Munich Medical Center, Munich, 80337, Germany. 175. ib-salut, Area de Salut de Menorca, Spain. 176. Fundació Institut d’Investigació Sanitària Illes Balears – IdISBa, Spain. 177. European Centre for Environment and Human Health, University of Exeter, Truro, TR1 3HD, UK. 178. Department of Medicine, University of Turku, Turku, Finland. 179. Division of Medicine, Turku University Hospital, Turku, Finland. 180. Center for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Spain. 181. Barcelonabeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain. 182. Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands. 183. Department of Public Health, Amsterdam Public Health Research Institute, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, 1105 AZ, The Netherlands. 184. Institute of Medical Statistics and Epidemiology, Technical University Munich, Munich, D-80333, Germany. 185. Institute of Medical Informatics, Biometry and Epidemiology, Ludwig Maximilians University, Munich, 81377, Germany. 186. Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH8 9AG, UK. 187. MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK. 188. Queensland Brain Institute, University of Queensland, QLD, Australia. 189. Genetics of Complex Traits, University of Exeter Medical School, Royal Devon & Exeter Hospital, Exeter, EX2 5DW, UK. 190. Department of Clinical Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, 1105 AZ, The Netherlands. 191. Division of Gastroenterology, Hepatology
and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA. 192. Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, 70210, Finland. 193. Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland. 194. IMIM (Hospital del Mar Medical Research Institute), Barcelona, 08003, Spain. 195. Biocenter Oulu, University of Oulu, Oulu, 90220, Finland. 196. Department of Genomics of Complexe Diseases, Imperial College, London, UK. 197. Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Diagnosvägen 15, SE-416 85 Gothenburg, Sweden. 198. Norwegian Institute of Public Health, Norway. 199. Bristol NIHR Biomedical Research Centre, Bristol, UK. 200. Department of Paediatrics, University of Cambridge, Cambridge, CB2 0QQ, UK. 201. Child and Adolescent Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands. 202. Social and Behavioral Sciences, Harvard TH Chan School of Public Health, Harvard University, Boston, USA. 203. Unit of Primary Care, Oulu University Hospital, Oulu, 90220, Finland. 204. Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Middlesex, UB8 3PH, UK. 205. Oxford National Institute for Health Research (NIHR) Biomedical Research Centre, Churchill Hospital, Oxford, OX3 7LE, UK.
EGG Membership
Members as of July 2018 are listed in alphabetical order.
Linda S Adair1, Emma Ahlqvist2, Tarunveer S Ahluwalia3,4,5, Peter Almgren2, Wei Ang6, Mustafa Atalay7, Robin N Beaumont8, Jacques S Beckmann9, Hans Bisgaard3, Tom Bond10, Klaus Bønnelykke3, Dorret I Boomsma11,12,13,14, Judith B Borja15,16, Jonathan P Bradfield17,18, Mariona Bustamante19,20,21, Alana Cavadino22,23, Pimphen Charoen10,24, Lachlan Coin25, Cyrus Cooper26, Diana L Cousminer27,28, John A Curtin29, Adnan Custovic30, Shikta Das23, Felix R Day31, N Maneka De Silva10, George V Dedoussis32, Paul Elliott10, Johan G Eriksson33,34,35, David M Evans36,37,38, João Fadista39, Bjarke Feenstra39, Janine F Felix40,41,42, Timothy M Frayling8, Rachel M Freathy8,36, Romy Gaillard41, Frank Geller39, Vincente Gilsanz43, Struan FA Grant17,27,28,44, Niels Grarup4, Leif Groop2,45, Monica Guxens19,20,21, Dexter Hadley46, Hakon Hakonarson17,27,44, Torben Hansen4, Andrew T Hattersley8,47, M Geoffrey Hayes48, Johannes Hebebrand49, Joachim Heinrich50,51, Øyvind Helgeland52,53,54, Tine B Henriksen55, Anke Hinney49, Joel N Hirschhorn56,57,58, Marie-France Hivert59,60,61, Berthold Hocher62,63, John W Holloway64, Momoko Horikoshi65,66,67, Jouke-Jan Hottenga11,12,14, Elina Hyppönen23,68,69, Bo Jacobsson54,70, Vincent WV Jaddoe40,41,42, Marjo-Riitta Järvelin10,71,72,73,74, Stefan Johansson52,75, Heidi J Kalkwarf76, Marjan Kerkhof77, Antje Körner78,79, Sailesh Kotecha80, Eskil Kreiner-Møller3,81, Benard Kulohoma65, Zoltán Kutalik82,83, Timo A Lakka7,84,85, Joan M Lappe86, Debbie A Lawlor36,37,87, Terho Lehtimäki88,89, Alexandra M Lewin10, Cecilia M Lindgren65,90,91, Virpi Lindi7, Allan Linneberg92,93, Xueping Liu39, Jun Liu41, William L Lowe Jr48, Ronald CW Ma94,95,96, Aurélien Macé82, Reedik Mägi97, Per Magnus98, Anubha Mahajan65,66, Nina S McCarthy99, Mark I McCarthy65,66,100, Mads Melbye39,101, Karen L Mohlke102, Claire Monnereau40,41,42, Dennis O Mook-Kanamori103,104, Camilla S Morgen105, Andrew P Morris65,97,106, Jeffrey C Murray107, Ronny Myhre108, Pål R Njølstad52,53, Ellen A Nohr109, Ioanna Ntalla110, Paul O’Reilly111, Sharon E Oberfield112, Emily Oken113, Ken K Ong31,114, Kalliope Panoutsopoulou115, Oluf Pedersen4, Craig E Pennell116, John RB Perry31, Niina Pitkänen117, Beate St Pourcain36,118, Christine Power23, Rashmi B Prasad2, Inga Prokopenko65,119, Olli T Raitakari117,120, Rebecca M Reynolds121, Rebecca C Richmond36,37, Alina Rodriguez10,122, Rany Salem57,123,124,125, Seang-Mei Saw126,127, Theresia M Schnurr4, Sylvain Sebert10,71,73,128, John A Shepherd129, Angela Simpson29, Line Skotte39, Thorkild IA Sørensen4,36,105, Marie Standl50, Eric AP Steegers130, David P Strachan131, Jordi Sunyer19,20,21,132, Michelle Taylor36,37, Yik-Ying Teo126,133,134, Elisabeth Thiering50,135, Nicholas J Timpson36,37, Jessica Tyrrell8,136, André G Uitterlinden40,41,137, Cornelia M van Duijn41, Suzanne Vogelezang40,41,42, Tanja GM Vrijkotte138, Carol A Wang116, Nicole M Warrington38, William J Watkins80, H-Erich Wichmann50,139,140, Elisabeth E Widén45, Gonneke Willemsen11,12,14, James F Wilson141,142, Hanieh Yaghootkar143, Mohammad Hadi Zafarmand138,144, Eleftheria Zeggini115, Babette S Zemel145
1. Department of Nutrition, University of North Carolina, Chapel Hill, NC 27599, USA. 2. Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, SE-205 02, Sweden. 3. COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, 2900 Hellerup, Denmark. 4. Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, DK-2200, Denmark. 5. Steno Diabetes Center Copenhagen, Gentofte, 2820, Denmark. 6. Division of Obstetrics and Gynaecology, The University of Western Australia, Crawley, WA, 6009, Australia. 7. Institute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, 70211, Finland. 8. Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter, EX2 5DW, UK. 9. University of Lausanne, Lausanne, CH-1015, Switzerland. 10. Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, W2 1PG, UK. 11. Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, 1081 BT, The Netherlands. 12. Amsterdam Public Health, Amsterdam, The Netherlands. 13. Amsterdam Reproduction and Development, Amsterdam, The Netherlands. 14. Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, 1081 HV, The Netherlands. 15. USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City, 6000, Philippines. 16. Department of Nutrition and Dietetics, University of San Carlos, Cebu City, 6000, Philippines. 17. Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA. 18. Quantinuum Research LLC, San Diego, CA, 92101, USA. 19. ISGlobal, Institute for Global Health, Barcelona, 08003, Spain. 20. Universitat Pompeu Fabra (UPF), Barcelona, 08003, Spain. 21. CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, 28029, Spain. 22. Section of Epidemiology & Biostatistics, School of Population Health, University of Auckland, Auckland, New Zealand. 23. Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, WC1N 1EH, UK. 24. Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand. 25. Institute for Molecular Bioscience, University of Queensland, QLD, Australia. 26. Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, Southampton, SO17 1BJ, UK. 27. Division of Human Genetics, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA. 28. Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104, USA. 29. Division of Infection Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, M13 9NT, UK. 30. Department of Paediatrics, Imperial College London, London, SW7 2AZ, UK. 31. MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK. 32. Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, 17671, Greece. 33. National Institute for Health and Welfare, Helsinki, 00271, Finland. 34. Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, 00014, Finland. 35. Folkhälsan Research Center, Helsinki, 00250, Finland. 36. Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, BS8 2BN, UK. 37. Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK. 38. University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD, 4072, Australia. 39. Department of Epidemiology Research, Statens Serum Institute, Copenhagen, DK-2300, Denmark. 40. The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 41. Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 42. Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 43. Department of Radiology, Children’s Hospital Los Angeles, Los Angeles, CA 90027, USA. 44. Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. 45. Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland. 46. Department of Pediatrics, University of California San Francisco School of Medicine, San Francisco, CA 94143, USA. 47. NIHR Exeter Clinical Research Facility, University of Exeter Medical School and Royal Devon and Exeter NHS Foundation Trust, Exeter, EX2 5DW, UK. 48. Department of Medicine, Division of Endocrinology, Metabolism, and Molecular Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. 49. Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, 45141, Germany. 50. Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany. 51. Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital of Ludwig Maximilians University, Munich, Germany. 52. KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, N-5020, Norway. 53. Department of Pediatrics, Haukeland University Hospital, Bergen, 5021, Norway. 54. Department of Genetics and Bioinformatics, Domain of Health Data and Digitalisation, Norwegian Institute of Public Health, Oslo, N-0473, Norway. 55. Department of Paediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus N, DK-8200, Denmark. 56. Programs in Metabolism and Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. 57. Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. 58. Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, MA, 02115, USA. 59. Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, MA 02215, USA. 60. Diabetes Center, Massachusetts General Hospital, Boston, MA 02114, USA. 61. Department of Medicine, Universite de Sherbrooke, Sherbooke, QC J1K 2R1, Canada. 62. Institute of Nutritional Science, University of Potsdam, Nuthetal, 14558, Germany. 63. The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China. 64. Human Development & Health, Faculty of Medicine, University of Southampton, Southampton, SO17 1BJ, UK. 65. Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK. 66. Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, OX3 7LE, UK. 67. RIKEN, Centre for Integrative Medical Sciences, Laboratory for Endocrinology, Metabolism and Kidney diseases, Yokohama, Kanagawa, 230-0045, Japan. 68. Australian Centre for Precision Health, University of South Australia Cancer Research Institute, Adelaide, SA, 5001, Australia. 69. South Australian Health and Medical Research Institute, Adelaide, SA, 5001, Australia. 70. Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Diagnosvägen 15, SE-416 85 Gothenburg, Sweden. 71. Biocenter Oulu, University of Oulu, Oulu, 90220, Finland. 72. Unit of Primary Care, Oulu University Hospital, Oulu, 90220, Finland. 73. Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, FI-90014, Finland. 74. Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Middlesex, UB8 3PH, UK. 75. Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway. 76. Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA. 77. Observational & Pragmatic Research Institute Pte Ltd, Singapore, Singapore. 78. Pediatric Research Center, Department of Women´s & Child Health, University of Leipzig, Leipzig, 04109, Germany. 79. IFB Adiposity Diseases, University of Leipzig, Leipzig, 04109, Germany. 80. Department of Child Health, School of Medicine, Cardiff Univeristy, Cardiff, CF10 3AT, UK. 81. Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, DK-2100, Denmark. 82. Institute of Social and Preventive Medicine, Lausanne University Hospital (CHUV), Lausanne, 1011, Switzerland. 83. Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland. 84. Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, 70210, Finland. 85. Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland. 86. Division of Endocrinology, Department of Medicine, Creighton University, Omaha, NE 68178, USA. 87. Bristol NIHR Biomedical Research Centre, Bristol, UK. 88. Department of Clinical Chemistry, Fimlab Laboratories, Tampere University Hospital, Tampere, Finland. 89. Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33520, Finland. 90. Li Ka Shing Centre for Health Information and Discovery, The Big Data Institute, University of Oxford, Oxford, OX3 7LF, UK. 91. The Broad Institute of Harvard and MIT, Cambridge, USA. 92. Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg, 2000, Denmark. 93. Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. 94. Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China. 95. Li Ka Shing
Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China. 96. Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China. 97. Estonian Genome Center, University of Tartu, Tartu, 50090, Estonia. 98. Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, N-0403, Norway. 99. Centre for Genetic Origins of Health and Disease (GOHaD), The University of Western Australia, Crawley, WA, 6000, Australia. 100. Oxford National Institute for Health Research (NIHR) Biomedical Research Centre, Churchill Hospital, Oxford, OX3 7LE, UK. 101. Department of Medicine, Stanford School of Medicine, Stanford, CA 94305, USA. 102. Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA. 103. Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands. 104. Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands. 105. Department of Public Health, Section of Epidemiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Copenhagen, DK-1014, Denmark. 106. Department of Biostatistics, University of Liverpool, Liverpool, L69 3GL, UK. 107. Department of Pediatrics, University of Iowa, Iowa City, IA 52242, USA. 108. Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, N-0403, Norway. 109. Research Unit for Gynaecology and Obstetrics, Institute of Clinical Research, University of Southern Denmark, Odense, DK-5000, Denmark. 110. William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK. 111. Medical Research Council (MRC), Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, SE5 8AF, UK. 112. Division of Pediatric Endocrinology, Diabetes, and Metabolism, Department of Pediatrics, Columbia University Medical Center, New York, NY 10032, USA. 113. Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA. 114. Department of Paediatrics, University of Cambridge, Cambridge, CB2 0QQ, UK. 115. Wellcome Sanger Institute, Hinxton, Cambridgeshire, CB10 1HH, UK. 116. School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle, Callaghan, NSW, 2308, Australia. 117. Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20014, Finland. 118. Max Planck Institute for Psycholinguistics, Nijmegen, 6525 XD, The Netherlands. 119. Section of Genomics of Common Disease, Department of Medicine, Imperial College London, London, SW7 2AZ, UK. 120. Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, 20520, Finland. 121. BHF Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, Edinburgh, EH16 4TJ, UK. 122. Department of Psychology, Mid Sweden University, Östersund, SE-831 25, Sweden. 123. Department of Medicine, Division of Endocrinology, Boston Children’s Hospital, Boston, MA 02115, USA. 124. Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. 125. Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, MA 02115, USA. 126. Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore, 119077, Singapore. 127. Singapore Eye Research Institute, Singapore, 168751, Singapore. 128. Department of Genomics of Complexe Diseases, Imperial College, London, UK. 129. Department of Epidemiology, Cancer Center, University of Hawaii (Manoa), Honolulu, Hawaii, 96813, USA. 130. Department of Obstetrics and Gynecology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 131. Population Health Research Institute, St George’s University of London, London, SW17 0RE, UK. 132. IMIM (Hospital del Mar Medical Research Institute), Barcelona, 08003, Spain. 133. Department of Statistics and Applied Probability, National University of Singapore, Singapore, 117546, Singapore. 134. Life Sciences Institute, National University of Singapore, Singapore, 117456, Singapore. 135. Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children’s Hospital, University of Munich Medical Center, Munich, 80337, Germany. 136. European Centre for Environment and Human Health, University of Exeter, Truro, TR1 3HD, UK. 137. Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 138. Department of Public Health, Amsterdam Public Health Research Institute, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, 1105 AZ, The Netherlands. 139. Institute of Medical Statistics and Epidemiology, Technical University Munich, Munich, D-80333, Germany. 140. Institute of Medical Informatics, Biometry and Epidemiology, Ludwig Maximilians University, Munich, 81377, Germany. 141. Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH8 9AG, UK. 142. MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK. 143. Genetics of Complex Traits, University of Exeter Medical School, Royal Devon & Exeter Hospital, Exeter, EX2 5DW, UK. 144. Department of Clinical Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, 1105 AZ, The Netherlands. 145. Division of Gastroenterology, Hepatology and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA.
EAGLE Membership
Members as of July 2018 are listed in alphabetical order.
Tarunveer S Ahluwalia1,3, Juha Auvinen4, Meike Bartels5,6,7, Jose Ramon Bilbao8,9,10, Hans Bisgaard1, Klaus Bønnelykke1, Dorret I Boomsma5,6,7,11, Jonathan P Bradfield12,13, Mariona Bustamante14,15,16, Zhanghua Chen17, John A Curtin18, Adnan Custovic19, George Davey Smith20,21, Gareth E Davies22, Liesbeth Duijts23,24,25, Peter R Eastwood26,27, Anders U Eliasen28,29, Xavier Estivill30, David M Evans20,21,31, Iryna O Fedko5,6, Janine F Felix23,32,33, W James Gauderman17, Frank Gilliland17, Raquel Granell21, Struan FA Grant12,34,35,36, Monica Guxens14,15,16, Hakon Hakonarson12,34,35, Catharina A Hartman37, Joachim Heinrich38,39, Anjali K Henders40, John Henderson21, Patrick Holt41, Jouke-Jan Hottenga5,6,7, Elina Hyppönen42,43,44, Carmen Iñíguez16,45,46, Bo Jacobsson47,48, Vincent WV Jaddoe23,32,33, Marjo-Riitta Järvelin4,49,50,51,52, Astanand Jugessur53,54,55, Mika Kähönen56,57, Jaakko Kaprio58,59, Ville Karhunen60, John P Kemp20,21,31, Gerard H Koppelman61, Ashish Kumar62,63, Jari Lahti64,65, Henrik Larsson66,67, Debbie A Lawlor20,21,68, Terho Lehtimäki69,70, Jin Li12, Paul Lichtenstein67, Sebastian Lundström71,72, Leo-Pekka Lyytikäinen69,70, Per Magnus54, Abdullah A Mamun73, Minna Mannikko4, Nicholas G Martin74, Hamdi Mbarek5,6,7,11, Sarah E Medland74, Erik Melén62,75, Christel M Middeldorp6,76,77, Jackob M Najman78, Michel G Nivard5,6, Ilja M Nolte79, Albertine J Oldehinkel37, Katja Pahkala80,81, Teemu Palviainen58, Lavinia Paternoster20,21, Craig E Pennell82, Göran Pershagen62,83, Niina Pitkänen80, Robert Plomin84, Beate St Pourcain20,85, Christine Power44, Lea Pulkkinen86, Katri Räikkönen65, Olli T Raitakari80,87, Rebecca C Richmond20,21, Fernando Rivadeneira23,32,88, Richard J Rose89, Loreto Santa-Marina16,90,91, James G Scott78,92,93, Sylvain Sebert4,49,50,94, Saskia Selzam84, Angela Simpson18, Patrick MA Sleiman12,35, Harold Snieder79, Marie Standl38, Camilla Stoltenberg95, David P Strachan96, Leon Straker97, Timo Strandberg4,98,99, Jordi Sunyer14,15,16,100, Elisabeth Thiering38,101, Henning Tiemeier102,103, Nicholas J Timpson20,21, Maties Torrent16,104,105, André G Uitterlinden23,32,88, Toos van Beijsterveldt5,6, Peter J van der Most79, Cornelia M van Duijn32, Jorma Viikari106,107, Natalia Vilor-Tejedor108,109, Judith M Vonk79,110, Tanja GM Vrijkotte111, Eero Vuoksimaa58, Carol A Wang82, Andrew JO Whitehouse41, Gonneke Willemsen5,6,7, Gail M Williams78, Naomi R Wray40,112, Shujing Xu17, Cheng-Jian Xu61, Lu Yi67, Mohammad Hadi Zafarmand111,113
1. COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, 2900 Hellerup, Denmark. 2. Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, DK-2200, Denmark. 3. Steno Diabetes Center Copenhagen, Gentofte, 2820, Denmark. 4. Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, FI-90014, Finland. 5. Amsterdam Public Health, Amsterdam, The Netherlands. 6. Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, 1081 BT, The Netherlands. 7. Netherlands Twin Register, Department of Biological Psychology, VU University, Amsterdam, 1081 HV, The Netherlands. 8. University of the Basque Country (UPV/EHU), Spain. 9. Biocruces Health Research Institute, Spain. 10. CIBER Diebetes y Enfermedades Metabólicas (CIBERDEM), Spain. 11. Amsterdam Reproduction and Development, Amsterdam, The Netherlands. 12. Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA. 13. Quantinuum Research LLC, San Diego, CA, 92101, USA. 14. ISGlobal, Institute for Global Health, Barcelona, 08003, Spain. 15. Universitat Pompeu Fabra (UPF), Barcelona, 08003, Spain. 16. CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, 28029, Spain. 17. Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA. 18. Division of Infection Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, M13 9NT, UK. 19. Department of Paediatrics, Imperial College London, London, SW7 2AZ, UK. 20. Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol, BS8 2BN, UK. 21. Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 2BN, UK. 22. Avera Institute for Human Genetics, Sioux Falls, South Dakota, USA. 23. The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 24. Department of Pediatrics, Division of Respiratory Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. 25. Department of Pediatrics, Division of Neonatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. 26. School of Human Sciences, The University of Western Australia, WA, Australia. 27. West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology & Sleep Medicine, Sir Charles Gairdner Hospital, WA, Australia. 28. Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Denmark. 29. Department of Bio and Health Informatics, Technical University of Denmark, Denmark. 30. Sidra Medicine Research Center, Sidra Medicine, Doha, Qatar. 31. University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD, 4072, Australia. 32. Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 33. Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 34. Division of Human Genetics, The Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA. 35. Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. 36. Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104, USA. 37. Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. 38. Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany. 39. Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital of Ludwig Maximilians University, Munich, Germany. 40. Institute for Molecular Bioscience, University of Queensland, QLD, Australia. 41. Telethon Kids Institute (TKI), The University of Western Australia, WA, Australia. 42. Australian Centre for Precision Health, University of South Australia Cancer Research Institute, Adelaide, SA, 5001, Australia. 43. South Australian Health and Medical Research Institute, Adelaide, SA, 5001, Australia. 44. Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, WC1N 1EH, UK. 45. Department of Statistics and Computational Research, Universitat de València, Spain. 46. Epidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, Spain. 47. Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Diagnosvägen 15, SE-416 85 Gothenburg, Sweden. 48. Department of Genetics and Bioinformatics, Domain of Health Data and Digitalisation, Norwegian Institute of Public Health, Oslo, N-0473, Norway. 49. Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, W2 1PG, UK. 50. Biocenter Oulu, University of Oulu, Oulu, 90220, Finland. 51. Unit of Primary Care, Oulu University Hospital, Oulu, 90220, Finland. 52. Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Middlesex, UB8 3PH, UK. 53. Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, N-0403, Norway. 54. Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, N-0403, Norway. 55. Department of Global Public Health and Primary Care, University of Bergen, Norway. 56. Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland. 57. Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland. 58. Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland. 59. Department of Public Health, University of Helsinki, Helsinki, Finland. 60. Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. 61. University of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children’s Hospital, GRIAC Research Institute Groningen, Groningen, The Netherlands. 62. Institute of Environmental Medicine, Karolinska Institutet, Sweden. 63. Department of Public Health Epidemiology, Unit of Chronic Disease Epidemiology, Swiss Tropical and Public Health Institute, Basel, University of Basel, Switzerland. 64. Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, Finland. 65. Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland. 66. School of Medicine Sciences, Örebro University, Sweden. 67. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Sweden. 68. Bristol NIHR Biomedical Research Centre, Bristol, UK. 69. Department of Clinical Chemistry, Fimlab Laboratories, Tampere University Hospital, Tampere, Finland. 70. Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33520, Finland. 71. Centre for Ethics, Law and Mental Health, University of Gothenburg, Sweden. 72. Gillberg Neuropsychiatry Centre, University of Gothenburg, Sweden. 73. Institute for Social Science Research, University of Queensland, QLD, Australia. 74. QIMR Berghofer Medical Research Institute, QLD, Australia. 75. Sachs’ Children’s Hospital, Sweden. 76. Child Health Research Centre, University of Queensland, Brisbane, QLD, Australia. 77. Child and Youth Mental Health Service, Children’s Health Queensland Hospital and Health Service, Brisbane, QLD, Australia. 78. School of Public Health, The University of Queensland, QLD, Australia. 79. Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. 80. Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20014, Finland. 81. Paavo Nurmi Centre, Sports and Exercise Medicine Unit, Department of Physical Activity and Health, University of Turku, Turku, Finland. 82. School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle, Callaghan, NSW, 2308, Australia. 83. Centre for Occupational and Environmental Medicine, Stockholm County Council, Sweden. 84. MRC Social, Genetic and Developmental Psychiatry Centre, King’s College London, London, UK. 85. Max Planck Institute for Psycholinguistics, Nijmegen, 6525 XD, The Netherlands. 86. Department of Psychology, University of Jyväskylä, Jyväskylä, Finland. 87. Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, 20520, Finland. 88. Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, 3015 CE, The Netherlands. 89. Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana, USA. 90. Subdirección de Salud Pública y Adicciones de Gipuzkoa, San Sebastián, Spain. 91. Instituto de Investigación Sanitaria Biodonostia, San Sebastián, Spain. 92. Metro North Mental Health Service, QLD, Australia. 93. Queensland Centre for Mental Health Research, QLD, Australia. 94. Department of Genomics of Complexe Diseases, Imperial College, London, UK. 95. Norwegian Institute of Public Health, Norway. 96. Population Health Research Institute, St George’s University of London, London, SW17 0RE, UK. 97. School of Physiotherapy and Exercise Science, Faculty of Health Sciences, Curtin University, Perth, WA, Australia. 98. Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland. 99. Clinicum, University of Helsinki, Helsinki, Finland. 100. IMIM (Hospital del Mar Medical Research Institute), Barcelona, 08003,
Spain. 101. Division
of Metabolic and Nutritional Medicine, Dr. von Hauner Children’s Hospital, University of Munich Medical Center, Munich, 80337, Germany. 102. Child and Adolescent Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands. 103. Social and Behavioral Sciences, Harvard TH Chan School of Public Health, Harvard University, Boston, USA. 104. ib-salut, Area de Salut de Menorca, Spain. 105. Fundació Institut d’Investigació Sanitària Illes Balears – IdISBa, Spain. 106. Department of Medicine, University of Turku, Turku, Finland. 107. Division of Medicine, Turku University Hospital, Turku, Finland. 108. Center for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Spain. 109. Barcelonabeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain. 110. Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands. 111. Department of Public Health, Amsterdam Public Health Research Institute, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, 1105 AZ, The Netherlands. 112. Queensland Brain Institute, University of Queensland, QLD, Australia. 113. Department of Clinical Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, 1105 AZ, The Netherlands.