Skip to main content
Erschienen in: Lasers in Medical Science 1/2010

01.01.2010 | Original Article

The effect of 904 nm low level laser on condylar growth in rats

verfasst von: Massoud Seifi, Arezoo Maghzi, Norbert Gutknecht, Maziar Mir, Mohammad Asna-Ashari

Erschienen in: Lasers in Medical Science | Ausgabe 1/2010

Einloggen, um Zugang zu erhalten

Abstract

A growth center of the mandible that contributes to its length and height is the mandibular condyle. Proliferation of prechondroblasts, followed by synthesis of the extracellular matrix and hypertrophy of the cartilage cells, governs the major part of condylar growth. The sample consisted of 54 male rats, weighing between 60 g and 80 g, divided randomly into three groups. Group I was the control group, group II was irradiated bilaterally, and group III was irradiated on the right side. Laser irradiation (λ = 904 nm, 2000 Hz, pulse length 200 ns and output power 4 mW) was performed, and the procedure was repeated after a 50-day interval. Two months later, the rats were killed. In a single blind manner the lengths of denuded mandibles and the lengths of mandibles on soft tissue were measured. The growth of the mandibles in the unilaterally irradiated group (P < 0.001) and the bilaterally irradiated group (P < 0.05) was significantly more than that in the control group. There was no significant difference between right and left condylar growth in the bilaterally irradiated group (P = 0.3). Soft tissue analysis also verified these results (P < 0.001). Histomorphometric results also revealed a significant difference between laser-irradiated groups and the control group (P < 0.01). We concluded that particular laser irradiation with the chosen parameters can stimulate condylar growth and subsequently cause mandibular advancement. These findings might be clinically relevant, indicating that low level laser irradiation can be used for further improvement of mandibular retrognathism.
Literatur
1.
Zurück zum Zitat Kuhberg AJ (2001) Steps in orthodontic treatment. In: Bishara SE (ed) Textbook of orthodontics. Saunders, St. Louis, pp 232–245 Kuhberg AJ (2001) Steps in orthodontic treatment. In: Bishara SE (ed) Textbook of orthodontics. Saunders, St. Louis, pp 232–245
2.
Zurück zum Zitat Spalding P (2001) Treatment of class II malocclusions. In: Bishara SE (ed) Textbook of orthodontics. Saunders, St. Louis, pp 324–374 Spalding P (2001) Treatment of class II malocclusions. In: Bishara SE (ed) Textbook of orthodontics. Saunders, St. Louis, pp 324–374
3.
Zurück zum Zitat Nicolau RA, Jorgetti V, Rigau J, Pacheco MTT, Reis LM, Zangaro RA (2003) Effect of low-power GaAlAs laser (660 nm) on bone structure and cell activity: an experimental animal study. Lasers Med Sci 18:89–94. doi:10.1007/s10103–003–0260-z CrossRef Nicolau RA, Jorgetti V, Rigau J, Pacheco MTT, Reis LM, Zangaro RA (2003) Effect of low-power GaAlAs laser (660 nm) on bone structure and cell activity: an experimental animal study. Lasers Med Sci 18:89–94. doi:10.​1007/​s10103–003–0260-z CrossRef
8.
Zurück zum Zitat Renno AC, McDonnell PA, Parizotto NA, Laakso EL (2007) The effects of laser irradiation on osteoblast and osteosarcoma cell proliferation and differentiation in vitro. Photomed Laser Surg 25:275–280. doi:10.1089/pho.2007.2055 CrossRefPubMed Renno AC, McDonnell PA, Parizotto NA, Laakso EL (2007) The effects of laser irradiation on osteoblast and osteosarcoma cell proliferation and differentiation in vitro. Photomed Laser Surg 25:275–280. doi:10.​1089/​pho.​2007.​2055 CrossRefPubMed
9.
Zurück zum Zitat Morrone G, Guzzardella GA, Torricelli P, Fini M, Giardino R (1998) In vitro experimental research of rabbit chondrocytes biostimulation with diode laser GaAlAs: a preliminary study. Artif Cells Blood Substit Immobil Biotechnol 26:437–439CrossRefPubMed Morrone G, Guzzardella GA, Torricelli P, Fini M, Giardino R (1998) In vitro experimental research of rabbit chondrocytes biostimulation with diode laser GaAlAs: a preliminary study. Artif Cells Blood Substit Immobil Biotechnol 26:437–439CrossRefPubMed
10.
Zurück zum Zitat Almeida-Lopes L, Rigau J, Zangaro RA, Guidugli-Neto J, Jaeger MM (2001) Comparison of the low level laser therapy effects on cultured human gingival fibroblasts proliferation using different irradiance and same fluence. Lasers Surg Med 29:179–184. doi:10.1002/lsm.1107 CrossRefPubMed Almeida-Lopes L, Rigau J, Zangaro RA, Guidugli-Neto J, Jaeger MM (2001) Comparison of the low level laser therapy effects on cultured human gingival fibroblasts proliferation using different irradiance and same fluence. Lasers Surg Med 29:179–184. doi:10.​1002/​lsm.​1107 CrossRefPubMed
11.
Zurück zum Zitat Kreisler M, Christoffers AB, Al-Haj H, Willershausen B, D’Hoedt B (2002) Low level 809-nm diode laser-induced in vitro stimulation of the proliferation of human gingival fibroblasts. Lasers Surg Med 30:365–369. doi:10.1002/lsm.10060 CrossRefPubMed Kreisler M, Christoffers AB, Al-Haj H, Willershausen B, D’Hoedt B (2002) Low level 809-nm diode laser-induced in vitro stimulation of the proliferation of human gingival fibroblasts. Lasers Surg Med 30:365–369. doi:10.​1002/​lsm.​10060 CrossRefPubMed
12.
Zurück zum Zitat Guzzardella GA, Morrone G, Torricelli P, Rocca M, Tigani D, Brodano GB, et al (2000) Assessment of low-power biostimulation on chondral lesions: an “in vivo” experimental study. Artif Cells Blood Substit Immobil Biotechnol 28:441–449CrossRefPubMed Guzzardella GA, Morrone G, Torricelli P, Rocca M, Tigani D, Brodano GB, et al (2000) Assessment of low-power biostimulation on chondral lesions: an “in vivo” experimental study. Artif Cells Blood Substit Immobil Biotechnol 28:441–449CrossRefPubMed
13.
Zurück zum Zitat Morrone G, Guzzardella GA, Torricelli P, Rocca M, Tigani D, Brodano GB, et al (2000) Osteochondral lesion repair of the knee in the rabbit after low-power diode GaAlAs laser biostimulation: an experimental study. Artif Cell Blood Substit Immobil Biotechnol 28:321–336CrossRef Morrone G, Guzzardella GA, Torricelli P, Rocca M, Tigani D, Brodano GB, et al (2000) Osteochondral lesion repair of the knee in the rabbit after low-power diode GaAlAs laser biostimulation: an experimental study. Artif Cell Blood Substit Immobil Biotechnol 28:321–336CrossRef
14.
Zurück zum Zitat Michel JL (2004) Treatment of molluscum contagiosum with 585 nm collagen remodeling pulsed dye laser. Eur J Dermatol 14:103–106PubMed Michel JL (2004) Treatment of molluscum contagiosum with 585 nm collagen remodeling pulsed dye laser. Eur J Dermatol 14:103–106PubMed
15.
Zurück zum Zitat Michel JL (2003) Treatment of hemangiomas with 595 nm pulsed dye laser dermobeam. Eur J Dermatol 13:136–141PubMed Michel JL (2003) Treatment of hemangiomas with 595 nm pulsed dye laser dermobeam. Eur J Dermatol 13:136–141PubMed
17.
Zurück zum Zitat De Pedro JA, Martin AP, Blanco M, Salvado M, Perez MA, Cardoso F, et al (2007) Histomorphometric study of femoral heads in hip osteoarthritis and osteoporosis. Histol Histopathol 22:1091–1097PubMed De Pedro JA, Martin AP, Blanco M, Salvado M, Perez MA, Cardoso F, et al (2007) Histomorphometric study of femoral heads in hip osteoarthritis and osteoporosis. Histol Histopathol 22:1091–1097PubMed
19.
20.
Zurück zum Zitat Parfitt AM, Drenzer MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, et al (1987) Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2:595–610PubMedCrossRef Parfitt AM, Drenzer MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, et al (1987) Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2:595–610PubMedCrossRef
21.
Zurück zum Zitat Dew DK, Supik L, Darrow CR (1993) Tissue repair using laser: a review. Orthopedics 16:581–587PubMed Dew DK, Supik L, Darrow CR (1993) Tissue repair using laser: a review. Orthopedics 16:581–587PubMed
22.
Zurück zum Zitat Dortbudak O, Haas R, Mallath-Pokorny G (2000) Biostimulation of bone marrow cells with a diode soft laser. Clin Oral Implants Res 11:540–545CrossRefPubMed Dortbudak O, Haas R, Mallath-Pokorny G (2000) Biostimulation of bone marrow cells with a diode soft laser. Clin Oral Implants Res 11:540–545CrossRefPubMed
23.
Zurück zum Zitat Silva Junior AN, Pinheiro ALB, Oliveira MG, Weismann R, Pedreira Ramalho LM, Amadei Nicolau R, et al (2002) Computerized morphometric assessment of the effect of low-level laser therapy on bone repair: an experimental animal study. J Clin Laser Med Surg 20:83–87CrossRefPubMed Silva Junior AN, Pinheiro ALB, Oliveira MG, Weismann R, Pedreira Ramalho LM, Amadei Nicolau R, et al (2002) Computerized morphometric assessment of the effect of low-level laser therapy on bone repair: an experimental animal study. J Clin Laser Med Surg 20:83–87CrossRefPubMed
24.
Zurück zum Zitat Ozawa Y, Shimizu N, Mishima H, Kariya G, Yamaguchi M, Takiguchi H, et al (1995) Stimulatory effects of low-power laser irradiation on bone formation in vitro. Proc SPIE 1984: 281–288 Ozawa Y, Shimizu N, Mishima H, Kariya G, Yamaguchi M, Takiguchi H, et al (1995) Stimulatory effects of low-power laser irradiation on bone formation in vitro. Proc SPIE 1984: 281–288
Metadaten
Titel
The effect of 904 nm low level laser on condylar growth in rats
verfasst von
Massoud Seifi
Arezoo Maghzi
Norbert Gutknecht
Maziar Mir
Mohammad Asna-Ashari
Publikationsdatum
01.01.2010
Verlag
Springer-Verlag
Erschienen in
Lasers in Medical Science / Ausgabe 1/2010
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-009-0651-x

Weitere Artikel der Ausgabe 1/2010

Lasers in Medical Science 1/2010 Zur Ausgabe