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Erschienen in: International Journal of Colorectal Disease 11/2017

20.09.2017 | Original Article

The effect of a geriatric evaluation on treatment decisions for older patients with colorectal cancer

verfasst von: N. M. Verweij, E. T. D. Souwer, A. H. W. Schiphorst, H. A. Maas, J. E. A. Portielje, A. Pronk, F. van den Bos, M. E. Hamaker

Erschienen in: International Journal of Colorectal Disease | Ausgabe 11/2017

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Abstract

Background

Treating elderly colorectal cancer patients can be challenging. It is very important to carefully weigh the risks and benefits of potential treatments in individual patients. This treatment decision making can be guided by geriatric consultation. Our aim was to assess the effect of a geriatric evaluation on treatment decisions for older patients with colorectal cancer.

Methods

Colorectal cancer patients who were referred for a geriatric consultation between 2013 and 2015 in three Dutch teaching hospitals were included in a prospective database. The outcome of geriatric assessment, non-oncological interventions and geriatricians’ treatment recommendations were evaluated.

Results

The total number of included referrals was 168. The median age was 81 years (range 60–94). Most patients (71%) had colon cancer and 49% had tumour stage III disease. The reason for geriatric consultation was uncertainty regarding the optimal oncologic treatment in 139 patients (83%). Overall 93% of patients suffered from geriatric impairments; non-oncological interventions that followed after geriatric consultation was mostly aimed at malnutrition. The geriatrician recommended the ‘more intensive treatment’ option in 69% and the ‘less intensive treatment’ option in 31% of which 63% ‘supportive care only’.

Conclusion

Geriatric consultation can be useful in treatment decision making in elderly patients with colorectal cancer. It may lead to changes in the treatment plan for individual cases and may result in an additional optimisation of patient’s health status prior to treatment.
Literatur
1.
Zurück zum Zitat Verweij NM, Schiphorst AH, Maas HA, Zimmerman DD, van den Bos F, Pronk A, Borel Rinkes IHM, Hamaker ME (2016) Colorectal cancer resections in the oldest old between 2011 and 2012 in The Netherlands. Ann Surg Oncol 23(6):1875–1882CrossRefPubMed Verweij NM, Schiphorst AH, Maas HA, Zimmerman DD, van den Bos F, Pronk A, Borel Rinkes IHM, Hamaker ME (2016) Colorectal cancer resections in the oldest old between 2011 and 2012 in The Netherlands. Ann Surg Oncol 23(6):1875–1882CrossRefPubMed
2.
Zurück zum Zitat Dekker JW, van den Broek CB, Bastiaannet E et al (2011) Importance of the first postoperative year in the prognosis of elderly colorectal cancer patients. Ann Surg Oncol 18(6):1533–1539CrossRefPubMedPubMedCentral Dekker JW, van den Broek CB, Bastiaannet E et al (2011) Importance of the first postoperative year in the prognosis of elderly colorectal cancer patients. Ann Surg Oncol 18(6):1533–1539CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Hamaker ME, Prins MC, Schiphorst AH et al (2015) Long-term changes in physical capacity after colorectal cancer treatment. J Geriatr Oncol 6(2):153–164CrossRefPubMed Hamaker ME, Prins MC, Schiphorst AH et al (2015) Long-term changes in physical capacity after colorectal cancer treatment. J Geriatr Oncol 6(2):153–164CrossRefPubMed
4.
Zurück zum Zitat Hamaker ME, Prins MC, Stauder R (2014) The relevance of a geriatric assessment for elderly patients with a haematological malignancy: a systematic review. Leuk Res 38:275–283CrossRefPubMed Hamaker ME, Prins MC, Stauder R (2014) The relevance of a geriatric assessment for elderly patients with a haematological malignancy: a systematic review. Leuk Res 38:275–283CrossRefPubMed
5.
Zurück zum Zitat Wildiers H, Heeren P, Puts M et al (2014) International Society of Geriatric Oncology consensus on geriatric assessment in older patients with cancer. J Clin Oncol 32:2595–2603CrossRefPubMedPubMedCentral Wildiers H, Heeren P, Puts M et al (2014) International Society of Geriatric Oncology consensus on geriatric assessment in older patients with cancer. J Clin Oncol 32:2595–2603CrossRefPubMedPubMedCentral
6.
Zurück zum Zitat Extermann M, Aapro M, Bernabei R et al (2005) Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG). Crit Rev Oncol Hematol 55:241–252CrossRefPubMed Extermann M, Aapro M, Bernabei R et al (2005) Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG). Crit Rev Oncol Hematol 55:241–252CrossRefPubMed
7.
Zurück zum Zitat Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383CrossRefPubMed Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383CrossRefPubMed
9.
Zurück zum Zitat Verweij NM, Schiphorst AHW, Pronk A et al (2016) Physical performance measures for predicting outcome in cancer patients: a systematic review. Acta Oncol 8:1–6 Verweij NM, Schiphorst AHW, Pronk A et al (2016) Physical performance measures for predicting outcome in cancer patients: a systematic review. Acta Oncol 8:1–6
10.
Zurück zum Zitat Brunello A, Sandri R, Extermann M (2009) Multidimensional geriatric evaluation for older cancer patients as a clinical and research tool. Cancer Treat Rev 35:487–492CrossRefPubMed Brunello A, Sandri R, Extermann M (2009) Multidimensional geriatric evaluation for older cancer patients as a clinical and research tool. Cancer Treat Rev 35:487–492CrossRefPubMed
11.
Zurück zum Zitat Extermann M, Hurria A (2007) Comprehensive geriatric assessment for older patients with cancer. J Clin Oncol 25:1824–1831CrossRefPubMed Extermann M, Hurria A (2007) Comprehensive geriatric assessment for older patients with cancer. J Clin Oncol 25:1824–1831CrossRefPubMed
12.
Zurück zum Zitat Verweij NM, Hamaker ME, Zimmerman DDE et al (2017) The impact of an ostomy on older colorectal cancer patients: a cross-sectional survey. Int J Colorectal Dis 32(1):89–94 Verweij NM, Hamaker ME, Zimmerman DDE et al (2017) The impact of an ostomy on older colorectal cancer patients: a cross-sectional survey. Int J Colorectal Dis 32(1):89–94
13.
Zurück zum Zitat Reynolds J, Chamberland-Tremblay A, Herrington JD et al (2017) High- versus low-dose leucovorin in the modified FOLFOX6 regimen for first-line treatment of metastatic colorectal cancer. J Oncol Pharm Pract 23(3):173–178 Reynolds J, Chamberland-Tremblay A, Herrington JD et al (2017) High- versus low-dose leucovorin in the modified FOLFOX6 regimen for first-line treatment of metastatic colorectal cancer. J Oncol Pharm Pract 23(3):173–178
14.
Zurück zum Zitat Lai P, Sud S, Zhang T et al (2016) Palliative chemotherapy in advanced colorectal cancer patients 80 years of age and older. Curr Oncol 23(3):144–153CrossRefPubMedPubMedCentral Lai P, Sud S, Zhang T et al (2016) Palliative chemotherapy in advanced colorectal cancer patients 80 years of age and older. Curr Oncol 23(3):144–153CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Hamaker ME, Schiphorst AH, ten Bokkel HD, Schaar C, van Munster BC (2014) The effect of a geriatric evaluation on treatment decisions for older cancer patients—a systematic review. Acta Oncol 53(3):289–296CrossRefPubMed Hamaker ME, Schiphorst AH, ten Bokkel HD, Schaar C, van Munster BC (2014) The effect of a geriatric evaluation on treatment decisions for older cancer patients—a systematic review. Acta Oncol 53(3):289–296CrossRefPubMed
16.
Zurück zum Zitat Verweij NM, Schiphorst AHW, Pronk A et al (2015) Conventional and laparoscopic colon resections in the elderly. World J Color Surg 5(2):Article 3 Verweij NM, Schiphorst AHW, Pronk A et al (2015) Conventional and laparoscopic colon resections in the elderly. World J Color Surg 5(2):Article 3
17.
Zurück zum Zitat Puts M, Sattar S, McWatters K et al A feasibility trial of geriatric assessment and integrated care plan for older cancer patients. Abstract 2016 SIOG conference, Milan. DOI: 10.1016/S1879-4068(16)30161-8 Puts M, Sattar S, McWatters K et al A feasibility trial of geriatric assessment and integrated care plan for older cancer patients. Abstract 2016 SIOG conference, Milan. DOI: 10.​1016/​S1879-4068(16)30161-8
18.
Zurück zum Zitat Li D, Kelly C, Trent M et al A randomized controlled trial of geriatric assessment guided multidisciplinary interventions: the first year experience. Abstract 2016 SIOG conference, Milan DOI: 10.1016/S1879-4068(16)30162-X Li D, Kelly C, Trent M et al A randomized controlled trial of geriatric assessment guided multidisciplinary interventions: the first year experience. Abstract 2016 SIOG conference, Milan DOI: 10.​1016/​S1879-4068(16)30162-X
Metadaten
Titel
The effect of a geriatric evaluation on treatment decisions for older patients with colorectal cancer
verfasst von
N. M. Verweij
E. T. D. Souwer
A. H. W. Schiphorst
H. A. Maas
J. E. A. Portielje
A. Pronk
F. van den Bos
M. E. Hamaker
Publikationsdatum
20.09.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
International Journal of Colorectal Disease / Ausgabe 11/2017
Print ISSN: 0179-1958
Elektronische ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-017-2883-8

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