Skip to main content
Erschienen in: Lasers in Medical Science 1/2021

01.07.2020 | Original Article

The effect of low-level laser therapy as an adjunct to periodontal surgery in the management of postoperative pain and wound healing: a systematic review and meta-analysis

verfasst von: Han Zhao, Jingchao Hu, Li Zhao

Erschienen in: Lasers in Medical Science | Ausgabe 1/2021

Einloggen, um Zugang zu erhalten

Abstract

The meta-analysis and systematic review aimed to evaluate the effect of low-level laser therapy (LLLT) as an adjunct to periodontal surgery in the management of postoperative pain and wound healing. An electronic search in 4 databases (PubMed, Embase, Cochrane, and OpenGrey) was conducted for randomized clinical trials reporting the effectiveness of LLLT used as an adjunct to periodontal surgery to alleviate pain and accelerate wound healing compared with surgery alone. Finally, 13 studies were eligible and included. The results showed a significant difference of pain relief between groups at day 3 post-surgery, whereas no difference was found at day 7. Moreover, a significant reduction was observed in the mean analgesic intake during the first week in the LLLT group. On day 14, the adjunctive use of LLLT showed significantly faster re-epithelialization and better wound healing in palatal donor sites following free gingival graft procedures. Based on the results, LLLT used as an adjunct to periodontal surgery positively influenced postsurgical pain control. Low power (≤ 500 mW) combined with energy density ≥ 5 J/cm2 might be more appropriate for postoperative pain relief. Moreover, adjunctive LLLT to free gingival grafts could significantly accelerate wound healing of palate sites at early healing phase. Multicenter studies using different LLL parameters without postsurgical analgesics are needed to determine optimal laser settings.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
2.
Zurück zum Zitat Melcher AH (1976) On the repair potential of periodontal tissues. J Periodontol 47:256–260CrossRef Melcher AH (1976) On the repair potential of periodontal tissues. J Periodontol 47:256–260CrossRef
3.
Zurück zum Zitat Kaner D, Soudan M, Zhao H, Gaßmann G, Schönhauser A, Friedmann A (2017) Early healing events after periodontal surgery: observations on soft tissue healing, microcirculation, and wound fluid cytokine levels. Int J Mol Sci 18(2). https://doi.org/10.3390/ijms18020283 Kaner D, Soudan M, Zhao H, Gaßmann G, Schönhauser A, Friedmann A (2017) Early healing events after periodontal surgery: observations on soft tissue healing, microcirculation, and wound fluid cytokine levels. Int J Mol Sci 18(2). https://​doi.​org/​10.​3390/​ijms18020283
7.
Zurück zum Zitat Hamblin MR, Demidova TN (2006) Mechanisms of low level light therapy - an introduction. In: Hamblin MR, Waynant RW, Anders J (eds) Mechanisms for low-light therapy I, The International Society for Optical Engineering, vol 61001. Bellingham, Washington, pp 1–12 Hamblin MR, Demidova TN (2006) Mechanisms of low level light therapy - an introduction. In: Hamblin MR, Waynant RW, Anders J (eds) Mechanisms for low-light therapy I, The International Society for Optical Engineering, vol 61001. Bellingham, Washington, pp 1–12
11.
Zurück zum Zitat Dima R, Francio VT, Towery C, Davani S (2017) Review of literature on low-level laser therapy benefits for nonpharmacological pain control in chronic pain and osteoarthritis. Altern Ther Health Med 23(7):221–222 Dima R, Francio VT, Towery C, Davani S (2017) Review of literature on low-level laser therapy benefits for nonpharmacological pain control in chronic pain and osteoarthritis. Altern Ther Health Med 23(7):221–222
15.
Zurück zum Zitat Martius F (1923) Das Amdt-Schulz Grundgesetz. Munch Med Wschr 70:1005–1006 Martius F (1923) Das Amdt-Schulz Grundgesetz. Munch Med Wschr 70:1005–1006
18.
Zurück zum Zitat Moslemi N, Heidari M, Fekrazad R, Nokhbatolfoghahaie H, Yaghobee S, Shamshiri A et al (2014) Evaluation of the effect of 660nm low power laser on pain and healing in palatal donor site: a randomized controlled clinical trial. J Dent Med-Tehran Univ Med Sci 27:71–77 Moslemi N, Heidari M, Fekrazad R, Nokhbatolfoghahaie H, Yaghobee S, Shamshiri A et al (2014) Evaluation of the effect of 660nm low power laser on pain and healing in palatal donor site: a randomized controlled clinical trial. J Dent Med-Tehran Univ Med Sci 27:71–77
21.
Zurück zum Zitat Higgins JPT, Altman DG, Sterne JAC (2017) Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Churchill R, Chandler J, Cumpston MS (ed). Cochrane handbook for systematic reviews of interventions version 5.2.0 (updated June 2017). Cochrane, pp 1-73 Higgins JPT, Altman DG, Sterne JAC (2017) Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Churchill R, Chandler J, Cumpston MS (ed). Cochrane handbook for systematic reviews of interventions version 5.2.0 (updated June 2017). Cochrane, pp 1-73
28.
Zurück zum Zitat da Silva Neves FL, Silveira CA, Dias SB, Santamaria Júnior M, de Marco AC, Kerbauy WD, de Melo Filho AB, Jardini MA, Santamaria MP (2016) Comparison of two power densities on the healing of palatalwounds after connective tissue graft removal: randomized clinical trial. Lasers Med Sci 31:1371–1378. https://doi.org/10.1007/s10103-016-1988-6CrossRefPubMed da Silva Neves FL, Silveira CA, Dias SB, Santamaria Júnior M, de Marco AC, Kerbauy WD, de Melo Filho AB, Jardini MA, Santamaria MP (2016) Comparison of two power densities on the healing of palatalwounds after connective tissue graft removal: randomized clinical trial. Lasers Med Sci 31:1371–1378. https://​doi.​org/​10.​1007/​s10103-016-1988-6CrossRefPubMed
29.
Zurück zum Zitat Fernandes-Dias SB, Fonseca MV, Dos Santos NC, Mathias IF, Martinho FC, Junior MS, Jardini MA, Santamaria MP (2015) Effect of GaAIAs low-level laser therapy on the healing of human palate mucosa after connective tissue graft harvesting: randomized clinical trial. Lasers Med Sci 30:1695–1702. https://doi.org/10.1007/s10103-014-1685-2CrossRef Fernandes-Dias SB, Fonseca MV, Dos Santos NC, Mathias IF, Martinho FC, Junior MS, Jardini MA, Santamaria MP (2015) Effect of GaAIAs low-level laser therapy on the healing of human palate mucosa after connective tissue graft harvesting: randomized clinical trial. Lasers Med Sci 30:1695–1702. https://​doi.​org/​10.​1007/​s10103-014-1685-2CrossRef
32.
Zurück zum Zitat Vieira JPPG, Lopes CB, DeMarco AC, de Melo Filho AB, Jardini A (2010) Clinical study of laser biomodulation (650 k) after free gingival grafts. J Oral Laser Applications 10:159–163 Vieira JPPG, Lopes CB, DeMarco AC, de Melo Filho AB, Jardini A (2010) Clinical study of laser biomodulation (650 k) after free gingival grafts. J Oral Laser Applications 10:159–163
45.
Zurück zum Zitat Hanna R, Agas D, Benedicenti S, Ferrando S, Laus F, Cuteri V, Lacava G, Sabbieti MG, Amaroli A (2019) A comparative study between the effectiveness of 980 nm photobiomodulation delivered by hand-piece with Gaussian vs. flat-top profiles on osteoblasts maturation. Front Endocrinol (Lausanne) 10:92. https://doi.org/10.3389/fendo.2019.00092 eCollection 2019CrossRef Hanna R, Agas D, Benedicenti S, Ferrando S, Laus F, Cuteri V, Lacava G, Sabbieti MG, Amaroli A (2019) A comparative study between the effectiveness of 980 nm photobiomodulation delivered by hand-piece with Gaussian vs. flat-top profiles on osteoblasts maturation. Front Endocrinol (Lausanne) 10:92. https://​doi.​org/​10.​3389/​fendo.​2019.​00092 eCollection 2019CrossRef
Metadaten
Titel
The effect of low-level laser therapy as an adjunct to periodontal surgery in the management of postoperative pain and wound healing: a systematic review and meta-analysis
verfasst von
Han Zhao
Jingchao Hu
Li Zhao
Publikationsdatum
01.07.2020
Verlag
Springer London
Erschienen in
Lasers in Medical Science / Ausgabe 1/2021
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-020-03072-5

Weitere Artikel der Ausgabe 1/2021

Lasers in Medical Science 1/2021 Zur Ausgabe