Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Klimawandel und Gesundheit Neues aus dem Markt COVID-19 Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende
Erweiterte Suche
Anmelden
nach oben
Indian Journal of Thoracic and Cardiovascular Surgery
Erschienen in: Indian Journal of Thoracic and Cardiovascular Surgery 3/2018

20.09.2018 | Review Article

The effect of storage solutions on endothelial function and saphenous vein graft patency

verfasst von: Ismail Bouhout, Walid Ben Ali, Louis Paul Perrault

Erschienen in: Indian Journal of Thoracic and Cardiovascular Surgery | Sonderheft 3/2018

Einloggen, um Zugang zu erhalten

Abstract

Vein graft failure is a complex mechanism that can be triggered immediately after surgical harvesting. Storage solutions have a major role in preventing endothelial cell damage during harvesting. While normal saline is still widely used, buffered solutions seem to better preserve endothelial integrity and function. This review aims to summarize the current literature surrounding vein graft storage solutions.
Literatur
1.
Goldman S, Zadina K, Moritz T, et al. Long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: Results from a department of veterans affairs cooperative study. J Am Coll Cardiol. 2004;44:2149–56.CrossRefPubMed
2.
McNeely C, Markwell S, Vassileva C. Trends in patient characteristics and outcomes of coronary artery bypass grafting in the 2000 to 2012 medicare population. Ann Thorac Surg. 2016;102:132–8.CrossRefPubMed
3.
de Vries MR, Simons KH, Jukema JW, Braun J, Quax PH. Vein graft failure: From pathophysiology to clinical outcomes. Nat Rev Cardiol. 2016;13:451–70.CrossRefPubMed
4.
Alexander JH, Hafley G, Harrington RA, et al. Efficacy and safety of edifoligide, an e2f transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: A randomized controlled trial. JAMA. 2005;294:2446–54.CrossRef
5.
Harskamp RE, Alexander JH, Schulte PJ, et al. Vein graft preservation solutions, patency, and outcomes after coronary artery bypass graft surgery: Follow-up from the prevent iv randomized clinical trial. JAMA Surg. 2014;149:798–805.CrossRefPubMedPubMedCentral
6.
Williams JB, Harskamp RE, Bose S, et al. The preservation and handling of vein grafts in current surgical practice: Findings of a survey among cardiovascular surgeons of top-ranked us hospitals. JAMA Surg. 2015;150:681–3.CrossRefPubMed
7.
Schachner T. Pharmacologic inhibition of vein graft neointimal hyperplasia. J Thorac Cardiovasc Surg. 2006;131:1065–72.CrossRefPubMed
8.
Schlitt A, Pruefer D, Buerke U, et al. Neutrophil adherence to activated saphenous vein and mammary endothelium after graft preparation. Ann Thorac Surg. 2006;81:1262–8.CrossRefPubMed
9.
Weiss DR, Juchem G, Kemkes BM, Gansera B, Nees S. Extensive deendothelialization and thrombogenicity in routinely prepared vein grafts for coronary bypass operations: Facts and remedy. Int J Clin Exp Med. 2009;2:95–113.PubMedPubMedCentral
10.
Shuhaiber JH, Evans AN, Massad MG, Geha AS. Mechanisms and future directions for prevention of vein graft failure in coronary bypass surgery. Eur J Cardiothorac Surg. 2002;22:387–96.CrossRefPubMed
11.
Sur S, Sugimoto JT, Agrawal DK. Coronary artery bypass graft: Why is the saphenous vein prone to intimal hyperplasia? Can J Physiol Pharmacol. 2014;92:531–45.CrossRefPubMed
12.
Lamm P, Juchem G, Milz S, Reichart B. Continuous graft perfusion: Optimizing the quality of saphenous vein grafts. Heart Surg Forum. 2002;5:S355–61.PubMed
13.
Lopes RD, Hafley GE, Allen KB, et al. Endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery. N Engl J Med. 2009;361:235–44.CrossRefPubMed
14.
15.
Hinokiyama K, Valen G, Tokuno S, Vedin JB, Vaage J. Vein graft harvesting induces inflammation and impairs vessel reactivity. Ann Thorac Surg. 2006;82:1458–64.CrossRefPubMed
16.
Owens CD, Wake N, Conte MS, Gerhard-Herman M, Beckman JA. In vivo human lower extremity saphenous vein bypass grafts manifest flow mediated vasodilation. J Vasc Surg. 2009;50:1063–70.CrossRefPubMedPubMedCentral
17.
Loscalzo J. Vascular matrix and vein graft failure. Is the message in the medium? Circulation. 2000;101:221–3.CrossRefPubMed
18.
Taggart DP, Ben Gal Y, Lees B, et al. A randomized trial of external stenting for saphenous vein grafts in coronary artery bypass grafting. Ann Thorac Surg. 2015;99:2039–45.CrossRefPubMed
19.
Kim KB, Hwang HY, Hahn S, Kim JS, Oh SJ. A randomized comparison of the saphenous vein versus right internal thoracic artery as a y-composite graft (save rita) trial: One-year angiographic results and mid-term clinical outcomes. J Thorac Cardiovasc Surg. 2014;148:901–7.CrossRefPubMed
20.
Catinella FP, Cunningham JN Jr, Srungaram RK, et al. The factors influencing early patency of coronary artery bypass vein grafts: Correlation of angiographic and ultrastructural findings. J Thorac Cardiovasc Surg. 1982;83:686–700.PubMed
21.
Sanchez AM, Wooldridge TA, Boerboom LE, Olinger GN, Almassi GH, Rusch NJ. Comparison of saphenous vein graft relaxation between plasma-lyte solution and normal saline solution. J Thorac Cardiovasc Surg. 1994;107:1445–53.PubMed
22.
Hickethier T, Dammrich J, Silber RE, Finster S, Elert O. Ultrastructural investigations for reducing endothelial cell damage of vein grafts during CABG-operation and practical consequences. J Cardiovasc Surg (Torino). 1999;40:71–6.
23.
Kown MH, Yamaguchi A, Jahncke CL, et al. L-arginine polymers inhibit the development of vein graft neointimal hyperplasia. J Thorac Cardiovasc Surg. 2001;121:971–80.CrossRefPubMed
24.
Biswas KS, Thatte HS, Najjar SF, et al. Multi-photon microscopy in the evaluation of human saphenous vein. J Surg Res. 2001;95:37–43.CrossRefPubMed
25.
Wilbring M, Tugtekin SM, Zatschler B, et al. Even short-time storage in physiological saline solution impairs endothelial vascular function of saphenous vein grafts. Eur J Cardiothorac Surg. 2011;40:811–5.PubMed
26.
Lawrie GM, Weilbacher DE, Henry PD. Endothelium-dependent relaxation in human saphenous vein grafts. Effects of preparation and clinicopathologic correlations. J Thorac Cardiovasc Surg. 1990;100:612–20.PubMed
27.
Bush HL Jr, Jakubowski JA, Curl GR, Deykin D, Nabseth DC. The natural history of endothelial structure and function in arterialized vein grafts. J Vasc Surg. 1986;3:204–15.CrossRefPubMed
28.
Chester AH, O'Neil GS, Tadjakarimi S, Borland JA, Yacoub MH. Effect of peri-operative storage solution on the vascular reactivity of the human saphenous vein. Eur J Cardiothorac Surg. 1993;7:399–404.CrossRefPubMed
29.
Cavallari N, Abebe W, Mingoli A, et al. Functional and morphological evaluation of canine veins following preservation in different storage media. J Surg Res. 1997;68:106–15.CrossRefPubMed
30.
Wilbring M, Ebner A, Schoenemann K, et al. Heparinized blood better preserves cellular energy charge and vascular functions of intraoperatively stored saphenous vein grafts in comparison to isotonic sodium-chloride-solution. Clin Hemorheol Microcirc. 2013;55:445–55.PubMed
31.
Gundry SR, Jones M, Ishihara T, Ferrans VJ. Optimal preparation techniques for human saphenous vein grafts. Surgery. 1980;88:785–94.PubMed
32.
Santoli E, Di Mattia D, Boldorini R, Mingoli A, Tosoni A, Santoli C. University of wisconsin solution and human saphenous vein graft preservation: Preliminary anatomic report. Eur J Cardiothorac Surg. 1993;7:548–52.CrossRefPubMed
33.
Dumanski A, Sopel M, Pelczar M, Szlapka M, Kustrzycki W, Zabel M. Influence of pressure on the endothelium of the saphenous vein coronary artery bypass graft. In Vivo. 2007;21:785–9.PubMed
34.
Tsakok M, Montgomery-Taylor S, Tsakok T. Storage of saphenous vein grafts prior to coronary artery bypass grafting: Is autologous whole blood more effective than saline in preserving graft function? Interact Cardiovasc Thorac Surg. 2012;15:720–5.CrossRefPubMedPubMedCentral
35.
Wise ES, Hocking KM, Cheung-Flynn J, Brophy CM. Balanced, ph-buffered preservation solutions improved physiologic response in human saphenous vein graft. Arterioscler Thromb Vasc Biol. 2014;34:A322.
36.
Bas M, Luther B, Knopf A, Suvorava T, Kojda G. Preservation of endothelial and smooth muscle function of human saphenous vein transplants. Exp Clin Transplant. 2016;14:86–92.PubMed
37.
Schaeffer U, Strohschneider T, Pilch H, et al. Influence of several solutions used in bypass surgery on the perrmeability of the endothelium of carotid arteries in new zealand rabbits. Thorac Cardiovasc Surg. 1999;47:240–3.CrossRefPubMed
38.
Garbe S, Zatschler B, Muller B, et al. Preservation of human artery function following prolonged cold storage with a new solution. J Vasc Surg. 2011;53:1063–70.CrossRefPubMed
39.
Veres G, Hegedus P, Barnucz E, et al. Tiprotec preserves endothelial function in a rat model. J Surg Res. 2016;200:346–55.CrossRefPubMed
40.
Wilbring M, Tugtekin SM, Zatschler B, et al. Preservation of endothelial vascular function of saphenous vein grafts after long-time storage with a recently developed potassium-chloride and n-acetylhistidine enriched storage solution. Thorac Cardiovasc Surg. 2013;61:656–62.PubMed
41.
He GW, Rosenfeldt FL, Angus JA. Pharmacological relaxation of the saphenous vein during harvesting for coronary artery bypass grafting. Ann Thorac Surg. 1993;55:1210–7.CrossRefPubMed
42.
Wise ES, Hocking KM, Luo W, et al. Traditional graft preparation decreases physiologic responses, diminishes viscoelasticity, and reduces cellular viability of the conduit: A porcine saphenous vein model. Vasc Med. 2016;21:413–21.CrossRefPubMedPubMedCentral
43.
Thatte HS, Biswas KS, Najjar SF, et al. Multi-photon microscopic evaluation of saphenous vein endothelium and its preservation with a new solution, GALA. Ann Thorac Surg. 2003;75:1145–52.CrossRefPubMed
44.
Thatte HS, Khuri SF. The coronary artery bypass conduit: I. Intraoperative endothelial injury and its implication on graft patency. Ann Thorac Surg. 2001;72:S2245–52.CrossRefPubMed
45.
Bhardwaj S, Roy H, Yla-Herttuala S. Gene therapy to prevent occlusion of venous bypass grafts. Expert Rev Cardiovasc Ther. 2008;6:641–52.CrossRefPubMed
46.
Chandiwal A, Balasubramanian V, Baldwin ZK, Conte MS, Schwartz LB. Gene therapy for the extension of vein graft patency: A review. Vasc Endovascular Surg. 2005;39:1–14.CrossRefPubMed
47.
Alexander JH, Ferguson TB Jr, Joseph DM, et al. The project of ex-vivo vein graft engineering via transfection iv (prevent iv) trial: Study rationale, design, and baseline patient characteristics. Am Heart J. 2005;150:643–9.CrossRefPubMed
48.
Stahli BE, Gebhard C, Duchatelle V, et al. Effects of the P-selectin antagonist inclacumab on myocardial damage after percutaneous coronary intervention according to timing of infusion: Insights from the SELECT-ACS trial. J Am Heart Assoc. 2016;5.pii:e004255.
49.
Nakao A, Huang CS, Stolz DB, et al. Ex vivo carbon monoxide delivery inhibits intimal hyperplasia in arterialized vein grafts. Cardiovasc Res. 2011;89:457–63.CrossRefPubMed
Metadaten
Titel
The effect of storage solutions on endothelial function and saphenous vein graft patency
verfasst von
Ismail Bouhout
Walid Ben Ali
Louis Paul Perrault
Publikationsdatum
20.09.2018
Verlag
Springer Singapore
Erschienen in
Indian Journal of Thoracic and Cardiovascular Surgery / Ausgabe Sonderheft 3/2018
Print ISSN: 0970-9134
Elektronische ISSN: 0973-7723
DOI
https://doi.org/10.1007/s12055-018-0720-5

Weitere Artikel der Sonderheft 3/2018

Indian Journal of Thoracic and Cardiovascular Surgery 3/2018 Zur Ausgabe

Review Article

Intraoperative graft assessment and imaging of native coronary arteries

Review Article

Current concepts in atherosclerosis

Video Article

Off-pump CABG and Zamvar pericardial fold

Review Article

A review of the AATS guidelines for the prevention and management of sternal wound infections

Review Article

Saphenous vein: advances

Review Article

The role of stem cells in treating coronary artery disease in 2018

Neu im Fachgebiet Chirurgie

23.04.2024 | Ablationstherapie | Nachrichten

Wie erfolgreich ist eine Re-Ablation nach Rezidiv?

23.04.2024 | Appendizitis | Nachrichten

Hinter dieser Appendizitis steckte ein Erreger

23.04.2024 | Operationsvorbereitung | Nachrichten

Mehr Schaden als Nutzen durch präoperatives Aussetzen von GLP-1-Agonisten?

19.04.2024 | EAU 2024 | Kongressbericht | Nachrichten

Ureterstriktur: Innovative OP-Technik bewährt sich
weitere anzeigen

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Aktuelle BDC Leitlinien-Webinare

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.