Skip to main content
Erschienen in: Journal of Anesthesia 4/2016

04.05.2016 | Original Article

The effect of superior cervical ganglion resection on peripheral facial palsy in rats

verfasst von: Motonari Atsumi, Katsuhisa Sunada

Erschienen in: Journal of Anesthesia | Ausgabe 4/2016

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Stellate ganglion block is performed to treat peripheral facial palsy because it increases blood flow and promotes nerve regeneration. Although stellate ganglion block increases blood flow around the facial nerve that runs outside the temporal bone, it may not affect blood flow inside the bone. Therefore, although stellate ganglion block is an effective procedure when the facial nerve is damaged outside the temporal bone, no studies have investigated the relationship between the site of nerve damage and the therapeutic effect of stellate ganglion block. Here, we investigated the efficacy of stellate ganglion block for facial palsy caused by facial nerve damage both inside and outside the temporal bone in rats.

Methods

A rat facial palsy model was created with nerve cooling that damaged the facial nerve inside or outside the temporal bone. A rat facial palsy stellate ganglion block model was also created by performing superior cervical ganglion resection on facial palsy model rats, and the duration of paralysis was examined.

Results

Facial nerve cooling inside and outside the temporal bone resulted in a mean duration of paralysis of 13.8 ± 1.6 days and 18.3 ± 2.2 days, respectively. Superior cervical ganglion resection in which the facial nerve had been cooled inside and outside the temporal bone reduced the mean duration of paralysis by 2.4 ± 1.3 days and 5.4 ± 1.3 days, respectively.

Conclusion

Stellate ganglion block was more effective in facial palsy caused by damage to the facial nerve outside, rather than inside, the temporal bone.
Literatur
1.
Zurück zum Zitat Tsuji S. Classic nerve treatment: Bell’s palsy. Neurol Ther. 2008;25:171–85. Tsuji S. Classic nerve treatment: Bell’s palsy. Neurol Ther. 2008;25:171–85.
2.
Zurück zum Zitat Salvaggio I, Adducci E, Dell’Aquila L, Rinaldi S, Marini M, Zappia L, Mascaro A. Facial pain: a possible therapy with stellate ganglion block. Pain Med. 2008;9:958–62.CrossRefPubMed Salvaggio I, Adducci E, Dell’Aquila L, Rinaldi S, Marini M, Zappia L, Mascaro A. Facial pain: a possible therapy with stellate ganglion block. Pain Med. 2008;9:958–62.CrossRefPubMed
3.
Zurück zum Zitat Milligan NS, Nash TP. Treatment of post-herpetic neuralgia. A review of 77 consecutive cases. Pain. 1985;23:381–6.CrossRefPubMed Milligan NS, Nash TP. Treatment of post-herpetic neuralgia. A review of 77 consecutive cases. Pain. 1985;23:381–6.CrossRefPubMed
4.
Zurück zum Zitat Melis M, Zawaki K, Al-Badawi E, Lobo S, Mehta N. Complex regional pain syndrome in the head and neck: a review of the literature. J Orofac Pain. 2002;16:93–104.PubMed Melis M, Zawaki K, Al-Badawi E, Lobo S, Mehta N. Complex regional pain syndrome in the head and neck: a review of the literature. J Orofac Pain. 2002;16:93–104.PubMed
5.
Zurück zum Zitat Miyamoto Y, Murakami S, Yanagihara N. Efficacy of cervical sympathectomy on the facial nerve blood flow. Facial N Res Jpn. 1995;15:57–60 (in Japanese). Miyamoto Y, Murakami S, Yanagihara N. Efficacy of cervical sympathectomy on the facial nerve blood flow. Facial N Res Jpn. 1995;15:57–60 (in Japanese).
6.
Zurück zum Zitat Fujita H, Murakami S, Ozawa T, Matsumoto Y, Yanagihara N. Experimental facial palsy induced by compression. Facial N Res Jpn. 1984;4:65–70. Fujita H, Murakami S, Ozawa T, Matsumoto Y, Yanagihara N. Experimental facial palsy induced by compression. Facial N Res Jpn. 1984;4:65–70.
7.
Zurück zum Zitat Hosomi Y. Histopathological study of the recovery process in experimental facial nerve palsy induced by freezing. Nippon Jibiinkoka Gakkai Kaiho. 1991;97:1683–91 (in Japanese).CrossRef Hosomi Y. Histopathological study of the recovery process in experimental facial nerve palsy induced by freezing. Nippon Jibiinkoka Gakkai Kaiho. 1991;97:1683–91 (in Japanese).CrossRef
8.
Zurück zum Zitat Sugita T. Facial nerve paralysis induced by herpes simplex virus infection in mice. Nippon Jibiinkoka Gakkai Kaiho. 1993;96:685–92 (in Japanese).CrossRefPubMed Sugita T. Facial nerve paralysis induced by herpes simplex virus infection in mice. Nippon Jibiinkoka Gakkai Kaiho. 1993;96:685–92 (in Japanese).CrossRefPubMed
9.
Zurück zum Zitat Ide C. Nerve regeneration and Schwann cell basal lamina: observations of the long-term regeneration. Arch Histol Jpn. 1983;46:243–57.CrossRefPubMed Ide C. Nerve regeneration and Schwann cell basal lamina: observations of the long-term regeneration. Arch Histol Jpn. 1983;46:243–57.CrossRefPubMed
10.
Zurück zum Zitat Ide C, Kato S. Peripheral nerve regeneration. Neurosci Res Suppl. 1990;13:463–8. Ide C, Kato S. Peripheral nerve regeneration. Neurosci Res Suppl. 1990;13:463–8.
11.
Zurück zum Zitat Nakashimo Y, Nakao Y, Tanimitsu N, Tagashira N. Clinical studies of peripheral facial nerve palsy treated at the Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital. J Hiroshima Med Assoc. 2008;61:490–6 (in Japanese). Nakashimo Y, Nakao Y, Tanimitsu N, Tagashira N. Clinical studies of peripheral facial nerve palsy treated at the Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital. J Hiroshima Med Assoc. 2008;61:490–6 (in Japanese).
12.
Zurück zum Zitat Morisada Y. The role of Schwann cells and macrophages in the rat sciatic nerve after axotomy. Kawasaki Med J. 1993;19:299–310 (in Japanese). Morisada Y. The role of Schwann cells and macrophages in the rat sciatic nerve after axotomy. Kawasaki Med J. 1993;19:299–310 (in Japanese).
14.
Zurück zum Zitat Minatogawa T. The blood supply of the facial nerve in the human temporal bone. Auris Nasus Larynx (Tokyo). 1980;7:7–18 .CrossRef Minatogawa T. The blood supply of the facial nerve in the human temporal bone. Auris Nasus Larynx (Tokyo). 1980;7:7–18 .CrossRef
15.
Zurück zum Zitat Bagger-Sjoback D, Thomander L. Vascular supply of the facial canal in the rat; a scanning electron microscope study with the microcorrosive technique. Am J Otol. 1985;6:135–41.PubMed Bagger-Sjoback D, Thomander L. Vascular supply of the facial canal in the rat; a scanning electron microscope study with the microcorrosive technique. Am J Otol. 1985;6:135–41.PubMed
16.
Zurück zum Zitat Peiterson E. The natural history of Bell’s palsy. Am J Otol. 1982;4:107–11. Peiterson E. The natural history of Bell’s palsy. Am J Otol. 1982;4:107–11.
17.
Zurück zum Zitat Corte MJB, Nieto CS, Ablanedo PA. Mother and sensory facial nerve grafts. Arch Otolaryngol. 1984;110:378–83.CrossRef Corte MJB, Nieto CS, Ablanedo PA. Mother and sensory facial nerve grafts. Arch Otolaryngol. 1984;110:378–83.CrossRef
18.
Zurück zum Zitat Yoshiyuki Y, Saito T, Saito H. Distribution of sympathetic nerve fibers to the facial nerve in the rat temporal bone. Facial N Res Jpn. 1998;18:46–8 (in Japanese). Yoshiyuki Y, Saito T, Saito H. Distribution of sympathetic nerve fibers to the facial nerve in the rat temporal bone. Facial N Res Jpn. 1998;18:46–8 (in Japanese).
19.
Zurück zum Zitat Inamura H, Koike Y, Ishikawa M, Tonosaki A. Effects of high dose steroid on the experimentally induced facial palsy. Nippon Jibiinkoka Gakkai Kaiho. 1990;93:1978–90 (in Japanese).CrossRefPubMed Inamura H, Koike Y, Ishikawa M, Tonosaki A. Effects of high dose steroid on the experimentally induced facial palsy. Nippon Jibiinkoka Gakkai Kaiho. 1990;93:1978–90 (in Japanese).CrossRefPubMed
Metadaten
Titel
The effect of superior cervical ganglion resection on peripheral facial palsy in rats
verfasst von
Motonari Atsumi
Katsuhisa Sunada
Publikationsdatum
04.05.2016
Verlag
Springer Japan
Erschienen in
Journal of Anesthesia / Ausgabe 4/2016
Print ISSN: 0913-8668
Elektronische ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-016-2181-6

Weitere Artikel der Ausgabe 4/2016

Journal of Anesthesia 4/2016 Zur Ausgabe

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.