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Osteoporosis International
Erschienen in: Osteoporosis International 5/2015

01.05.2015 | Original Article

The effects of differing resistance training modes on the preservation of bone mineral density in postmenopausal women: a meta-analysis

verfasst von: R. Zhao, M. Zhao, Z. Xu

Erschienen in: Osteoporosis International | Ausgabe 5/2015

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Abstract

Summary

This meta-analysis synthesized current evidence from 24 clinical trials to evaluate the impact of different resistance training modes on postmenopausal bone loss. Exercise interventions were categorized into two training modes, namely resistance-alone versus combined resistance training protocols. The combined resistance training protocols were defined as the combination of resistance training and high-impact or weight-bearing exercise. The results suggested that the combined resistance training protocols were effective in improving bone mineral density (BMD) at the femoral neck and lumbar spine.

Introduction

The current meta-analysis aimed to examine the effects of combined resistance and resistance-alone training protocols on the preservation of femoral neck and lumbar spine BMD in postmenopausal women.

Methods

An electronic database search was conducted in PubMed, EMBASE, SPORTDiscus, Web of Science, and ProQuest up to March 1, 2014 for the influence of resistance exercise on BMD in postmenopausal women. The study quality was evaluated. The effect sizes were estimated in terms of the standardized mean difference (SMD). A subgroup analysis was conducted by exercise categories.

Results

Twenty-four studies were included in the overall analysis of skeletal response to resistance exercise. The between-study heterogeneity was evident for the hip (I 2 = 46.5 %) and spine (I 2 = 62.3 %). The overall analysis suggested that resistance training significantly increased femoral neck BMD (SMD = 0.303, 95 % confidence interval (95 % CI) = 0.127–0.479, p = 0.001) and lumbar spine BMD (SMD = 0.311, 95 % CI = 0.115–0.507, p = 0.002) in postmenopausal women. However, subgroup analysis indicated that combined resistance training programs significantly affected both the hip BMD (SMD = 0.411, 95 % CI = 0.176–0.645, p = 0.001) and spine BMD (SMD = 0.431, 95 % CI = 0.159–0.702, p = 0.002), whereas resistance-alone protocols only produced nonsignificant positive effects both on the femoral neck and lumbar spine BMD.

Conclusions

Combined resistance exercise protocols appear effective in preserving femoral neck and lumbar spine BMD in postmenopausal women, whereas resistance-alone protocols only produced a nonsignificant positive effect.
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Literatur
1.
National Osteoporosis Foundation (2002) America’s bone health: the state of osteoporosis and low bone mass in our nation. National Osteoprosis Foundation, Washington
2.
Zhao D, Wu H, Liu Z (2006) Epidemiology of osteoporosis. In: Liu Z (ed) Bone mineral and clinic practice. Science and Technology Press, Beijing, pp 5–6
3.
Johnell O, Kanis JA (2006) An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int 17:1726–1733
4.
Moreira LD, Fronza FC, Dos Santos RN, Zach PL, Kunii IS, Hayashi LF, Teixeira LR, Kruel LF, Castro ML (2013) The benefits of a high-intensity aquatic exercise program (HydrOS) for bone metabolism and bone mass of postmenopausal women. J Bone Miner Metab. doi:10.​1007/​s00774-00013-00509-y PubMed
5.
Basat H, Esmaeilzadeh S, Eskiyurt N (2013) The effects of strengthening and high-impact exercises on bone metabolism and quality of life in postmenopausal women: a randomized controlled trial. J back Musculoskelet Rehabil 26:427–435PubMed
6.
7.
Ryan AS, Ivey FM, Hurlbut DE, Martel GF, Lemmer JT, Sorkin JD, Metter EJ, Fleg JL, Hurley BF (2004) Regional bone mineral density after resistive training in young and older men and women. Scand J Med Sci Sports 14:16–23CrossRefPubMed
8.
Bemben DA, Fetters NL, Bemben MG, Nabavi N, Koh ET (2000) Musculoskeletal responses to high- and low-intensity resistance training in early postmenopausal women. Med Sci Sports Exerc 32:1949–1957CrossRefPubMed
9.
Bemben DA, Palmer IJ, Bemben MG, Knehans AW (2010) Effects of combined whole-body vibration and resistance training on muscular strength and bone metabolism in postmenopausal women. Bone 47:650–656CrossRefPubMed
10.
Bocalini DS, Serra AJ, dos Santos L, Murad N, Levy RF (2009) Strength training preserves the bone mineral density of postmenopausal women without hormone replacement therapy. J Aging Health 21:519–527CrossRefPubMed
11.
Chilibeck PD, Davison KS, Whiting SJ, Suzuki Y, Janzen CL, Peloso P (2002) The effect of strength training combined with bisphosphonate (etidronate) therapy on bone mineral, lean tissue, and fat mass in postmenopausal women. Can J Physiol Pharmacol 80:941–950CrossRefPubMed
12.
Chuin A, Labonte M, Tessier D, Khalil A, Bobeuf F, Doyon CY, Rieth N, Dionne IJ (2009) Effect of antioxidants combined to resistance training on BMD in elderly women: a pilot study. Osteoporos Int J Established Result Coop Eur Found Osteoporos Natl Osteoporos Found U S A 20:1253–1258CrossRef
13.
Kerr D, Ackland T, Maslen B, Morton A, Prince R (2001) Resistance training over 2 years increases bone mass in calcium-replete postmenopausal women. J Bone Miner Res Off J Am Soc Bone Miner Res 16:175–181CrossRef
14.
Maddalozzo GF, Widrick JJ, Cardinal BJ, Winters-Stone KM, Hoffman MA, Snow CM (2007) The effects of hormone replacement therapy and resistance training on spine bone mineral density in early postmenopausal women. Bone 40:1244–1251CrossRefPubMed
15.
Marques EA, Wanderley F, Machado L, Sousa F, Viana JL, Moreira-Goncalves D, Moreira P, Mota J, Carvalho J (2011) Effects of resistance and aerobic exercise on physical function, bone mineral density, OPG and RANKL in older women. Exp Gerontol 46:524–532CrossRefPubMed
16.
Nelson ME, Fiatarone MA, Morganti CM, Trice I, Greenberg RA, Evans WJ (1994) Effects of high-intensity strength training on multiple risk factors for osteoporotic fractures. A randomized controlled trial. JAMA J Am Med Assoc 272:1909–1914CrossRef
17.
Pruitt LA, Jackson RD, Bartels RL, Lehnhard HJ (1992) Weight-training effects on bone mineral density in early postmenopausal women. J Bone Miner Res Off J Am Soc Bone Miner Res 7:179–185CrossRef
18.
Pruitt LA, Taaffe DR, Marcus R (1995) Effects of a one-year high-intensity versus low-intensity resistance training program on bone mineral density in older women. J Bone Miner Res Off J Am Soc Bone Miner Res 10:1788–1795CrossRef
19.
Rhodes EC, Martin AD, Taunton JE, Donnelly M, Warren J, Elliot J (2000) Effects of one year of resistance training on the relation between muscular strength and bone density in elderly women. Br J Sports Med 34:18–22CrossRefPubMedCentralPubMed
20.
Smidt GL, Lin SY, O’Dwyer KD, Blanpied PR (1992) The effect of high-intensity trunk exercise on bone mineral density of postmenopausal women. Spine 17:280–285CrossRefPubMed
21.
Verschueren SM, Roelants M, Delecluse C, Swinnen S, Vanderschueren D, Boonen S (2004) Effect of 6-month whole body vibration training on hip density, muscle strength, and postural control in postmenopausal women: a randomized controlled pilot study. J Bone Miner Res Off J Am Soc Bone Miner Res 19:352–359CrossRef
22.
Notomi T, Okazaki Y, Okimoto N, Saitoh S, Nakamura T, Suzuki M (2000) A comparison of resistance and aerobic training for mass, strength and turnover of bone in growing rats. Eur J Appl Physiol 83:469–474CrossRefPubMed
23.
Martyn-St James M, Carroll S (2006) High-intensity resistance training and postmenopausal bone loss: a meta-analysis. Osteoporos Int J Established Result Coop Eur Found Osteoporos Natl Osteoporos Found U S A 17:1225–1240CrossRef
24.
Bolton KL, Egerton T, Wark J, Wee E, Matthews B, Kelly A, Craven R, Kantor S, Bennell KL (2012) Effects of exercise on bone density and falls risk factors in post-menopausal women with osteopenia: a randomised controlled trial. J Sci Med Sport 15:102–109CrossRefPubMed
25.
Chilibeck PD, Vatanparast H, Pierson R, Case A, Olatunbosun O, Whiting SJ, Beck TJ, Pahwa P, Biem HJ (2013) Effect of exercise training combined with isoflavone supplementation on bone and lipids in postmenopausal women: a randomized clinical trial. J Bone Miner Res Off J Am Soc Bone Miner Res 28:780–793CrossRef
26.
Engelke K, Kemmler W, Lauber D, Beeskow C, Pintag R, Kalender WA (2006) Exercise maintains bone density at spine and hip EFOPS: a 3-year longitudinal study in early postmenopausal women. Osteoporos Int J Established Result Coop Eur Found Osteoporos Natl Osteoporos Found U S A 17:133–142CrossRef
27.
Going S, Lohman T, Houtkooper L et al (2003) Effects of exercise on bone mineral density in calcium-replete postmenopausal women with and without hormone replacement therapy. Osteoporos Int J Established Result Coop Eur Found Osteoporos Natl Osteoporos Found U S A 14:637–643CrossRef
28.
Jessup JV, Horne C, Vishen RK, Wheeler D (2003) Effects of exercise on bone density, balance, and self-efficacy in older women. Biol Res Nurs 4:171–180CrossRefPubMed
29.
Kemmler W, Engelke K, Weineck J, Hensen J, Kalender WA (2003) The Erlangen Fitness Osteoporosis Prevention Study: a controlled exercise trial in early postmenopausal women with low bone density-first-year results. Arch Phys Med Rehabil 84:673–682PubMed
30.
Kemmler W, Lauber D, Weineck J, Hensen J, Kalender W, Engelke K (2004) Benefits of 2 years of intense exercise on bone density, physical fitness, and blood lipids in early postmenopausal osteopenic women: results of the Erlangen Fitness Osteoporosis Prevention Study (EFOPS). Arch Intern Med 164:1084–1091CrossRefPubMed
31.
Kemmler W, von Stengel S, Bebenek M, Engelke K, Hentschke C, Kalender WA (2012) Exercise and fractures in postmenopausal women: 12-year results of the Erlangen Fitness and Osteoporosis Prevention Study (EFOPS). Osteoporos Int J Established Result Coop Eur Found Osteoporos Natl Osteoporos Found U S A 23:1267–1276CrossRef
32.
Milliken LA, Going SB, Houtkooper LB, Flint-Wagner HG, Figueroa A, Metcalfe LL, Blew RM, Sharp SC, Lohman TG (2003) Effects of exercise training on bone remodeling, insulin-like growth factors, and bone mineral density in postmenopausal women with and without hormone replacement therapy. Calcif Tissue Int 72:478–484CrossRefPubMed
33.
Villareal DT, Binder EF, Yarasheski KE, Williams DB, Brown M, Sinacore DR, Kohrt WM (2003) Effects of exercise training added to ongoing hormone replacement therapy on bone mineral density in frail elderly women. J Am Geriatr Soc 51:985–990CrossRefPubMed
34.
von Stengel S, Kemmler W, Engelke K, Kalender WA (2011) Effects of whole body vibration on bone mineral density and falls: results of the randomized controlled ELVIS study with postmenopausal women. Osteoporos Int J Established Result Coop Eur Found Osteoporos Natl Osteoporos Found U S A 22:317–325CrossRef
35.
Moher D, Liberati A, Tetzlaff J, Altman DG, Group P (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151(264–269):W264CrossRef
36.
Higgins J, Green S (2008) Cochrane reviewers’ handbook 5.0.1 (updated September 2008). The Cochrane Library. Wiley, Chichester
37.
Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, McQuay HJ (1996) Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 17:1–12CrossRefPubMed
38.
Milliken LA, Wilhelmy J, Martin CJ, Finkenthal N, Cussler E, Metcalfe L, Guido TA, Going SB, Lohman TG (2006) Depressive symptoms and changes in body weight exert independent and site-specific effects on bone in postmenopausal women exercising for 1 year. J Gerontol A: Biol Med Sci 61:488–494CrossRef
39.
Liu-Ambrose TY, Khan KM, Eng JJ, Heinonen A, McKay HA (2004) Both resistance and agility training increase cortical bone density in 75- to 85-year-old women with low bone mass: a 6-month randomized controlled trial. J Clin Densitom Off J Int Soc Clin Densitom 7:390–398CrossRef
40.
Tobias JH (2003) At the crossroads of skeletal responses to estrogen and exercise. Trends Endocrinol Metab TEM 14:441–443CrossRef
41.
Zhang J, Gao R, Cao P, Yuan W (2014) Additive effects of antiresorptive agents and exercise on lumbar spine bone mineral density in adults with low bone mass: a meta-analysis. Osteoporos Int J Established Result Coop Eur Found Osteoporos Natl Osteoporos Found U S A 25:1585–1594CrossRef
42.
Howe TE, Shea B, Dawson LJ, Downie F, Murray A, Ross C, Harbour RT, Caldwell LM, Creed G (2011) Exercise for preventing and treating osteoporosis in postmenopausal women. The Cochrane database of systematic reviews CD000333
43.
Martyn-St James M, Carroll S (2009) A meta-analysis of impact exercise on postmenopausal bone loss: the case for mixed loading exercise programmes. Br J Sports Med 43:898–908CrossRefPubMed
44.
Shaw JM, Snow CM (1998) Weighted vest exercise improves indices of fall risk in older women. J Gerontol A: Biol Med Sci 53:M53–M58CrossRef
45.
Snow CM, Shaw JM, Winters KM, Witzke KA (2000) Long-term exercise using weighted vests prevents hip bone loss in postmenopausal women. J Gerontol A: Biol Med Sci 55:M489–M491CrossRef
46.
El-Khoury F, Cassou B, Charles MA, Dargent-Molina P (2013) The effect of fall prevention exercise programmes on fall induced injuries in community dwelling older adults: systematic review and meta-analysis of randomised controlled trials. BMJ 347:f6234CrossRefPubMedCentralPubMed
47.
Karinkanta S, Piirtola M, Sievanen H, Uusi-Rasi K, Kannus P (2010) Physical therapy approaches to reduce fall and fracture risk among older adults. Nat Rev Endocrinol 6:396–407CrossRefPubMed
48.
Cummings SR, Black DM, Nevitt MC, Browner W, Cauley J, Ensrud K, Genant HK, Palermo L, Scott J, Vogt TM (1993) Bone density at various sites for prediction of hip fractures. The Study of Osteoporotic Fractures Research Group. Lancet 341:72–75CrossRefPubMed
49.
Lanyon LE (1987) Functional strain in bone tissue as an objective, and controlling stimulus for adaptive bone remodelling. J Biomech 20:1083–1093CrossRefPubMed
50.
Borer KT (2005) Physical activity in the prevention and amelioration of osteoporosis in women: interaction of mechanical, hormonal and dietary factors. Sports Med 35:779–830CrossRefPubMed
51.
Rubin CT, McLeod KJ (1994) Promotion of bony ingrowth by frequency-specific, low-amplitude mechanical strain. Clin Orthop Relat Res 298:165–174
52.
Martyn-St James M, Carroll S (2010) Effects of different impact exercise modalities on bone mineral density in premenopausal women: a meta-analysis. J Bone Miner Metab 28:251–267CrossRefPubMed
53.
54.
Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 62:e1–e34CrossRefPubMed
55.
Harris ST, Watts NB, Genant HK et al (1999) Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA J Am Med Assoc 282:1344–1352CrossRef
56.
Rabenda V, Mertens R, Fabri V, Vanoverloop J, Sumkay F, Vannecke C, Deswaef A, Verpooten GA, Reginster JY (2008) Adherence to bisphosphonates therapy and hip fracture risk in osteoporotic women. Osteoporos Int J Established Result Coop Eur Found Osteoporos Natl Osteoporos Found U S A 19:811–818CrossRef
57.
Cramer JA, Gold DT, Silverman SL, Lewiecki EM (2007) A systematic review of persistence and compliance with bisphosphonates for osteoporosis. Osteoporos Int J Established Result Coop Eur Found Osteoporos Natl Osteoporos Found U S A 18:1023–1031CrossRef
58.
59.
Miller PD, Derman RJ (2010) What is the best balance of benefits and risks among anti-resorptive therapies for postmenopausal osteoporosis? Osteoporos Int J Established Result Coop Eur Found Osteoporos Natl Osteoporos Found U S A 21:1793–1802CrossRef
60.
Rossouw JE, Anderson GL, Prentice RL et al (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trial. JAMA J Am Med Assoc 288:321–333CrossRef
61.
62.
Pildal J, Hrobjartsson A, Jorgensen KJ, Hilden J, Altman DG, Gotzsche PC (2007) Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials. Int J Epidemiol 36:847–857CrossRefPubMed
63.
Wood L, Egger M, Gluud LL, Schulz KF, Juni P, Altman DG, Gluud C, Martin RM, Wood AJ, Sterne JA (2008) Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: meta-epidemiological study. BMJ 336:601–605CrossRefPubMedCentralPubMed
64.
Wang Q, Nicholson PH, Suuriniemi M, Lyytikainen A, Helkala E, Alen M, Suominen H, Cheng S (2004) Relationship of sex hormones to bone geometric properties and mineral density in early pubertal girls. J Clin Endocrinol Metab 89:1698–1703CrossRefPubMed
65.
Karinkanta S, Heinonen A, Sievanen H, Uusi-Rasi K, Pasanen M, Ojala K, Fogelholm M, Kannus P (2007) A multi-component exercise regimen to prevent functional decline and bone fragility in home-dwelling elderly women: randomized, controlled trial. Osteoporos Int J Established Result Coop Eur Found Osteoporos Natl Osteoporos Found U S A 18:453–462CrossRef
66.
Metadaten
Titel
The effects of differing resistance training modes on the preservation of bone mineral density in postmenopausal women: a meta-analysis
verfasst von
R. Zhao
M. Zhao
Z. Xu
Publikationsdatum
01.05.2015
Verlag
Springer London
Erschienen in
Osteoporosis International / Ausgabe 5/2015
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI
https://doi.org/10.1007/s00198-015-3034-0

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