When keratinized tissue width around dental implants is poorly represented, the clinician could resort to autogenous soft tissue grafting. Autogenous soft tissue grafting procedures are usually associated with a certain degree of morbidity. Collagen matrices could be used as an alternative to reduce morbidity and intra-operatory times. The aim of this study was to assess the efficacy of a xenogeneic collagen matrix as a substitute for soft tissue grafting around dental implants.
Fifteen consecutive patients underwent a vestibuloplasty and keratinized tissue reconstruction around dental implants, both in the mandible and the maxilla, with a porcine collagen matrix. The so obtained keratinized tissues were measured and evaluated after 6 months and 1, 4, and 5 years.
The average gain of keratinized tissue was 5.7 mm. After 6 months, it was observed a resorption of 37%, after 1 year 48%, and after 5 years 59%. The mean gain of keratinized tissue after 5 years was 2.4 mm. Hemostatic effect and post-operative pain were evaluated too. All subjects referred minimal pain with no bleeding. No adverse reaction nor infection was noted.
The present study showed the efficacy of a porcine collagen matrix in keratinized tissue augmentation. The possibility to use a soft tissue substitute is a great achievement as morbidity decreases and bigger areas can be treated in a single surgery.
Chiapasco M, Casentini P, Zaniboni M. Bone augmentation procedures in implant dentistry. Int J Oral Maxillofac Implants. 2009;24(Suppl):237–59. PubMed
Grusovin MG, Coulthard P, Worthington HV, Esposito M. Maintaining and recovering soft tissue health around dental implants: a Cochrane systematic review of randomised controlled clinical trials. Eur J Oral Implantol. 2008;1(1):11–22. PubMed
Costello BJ, Betts NJ, Barber HD, Fonseca RJ. Preprosthetic surgery for the edentulous patients. Dent Clin N Am. 1996;40(1):19–38. PubMed
Zucchelli G, Mele M, Stefanini M, Mazzotti C, Marzadori M, Montebugnoli L, et al. Patient morbidity and root coverage outcome after subepithelial connective tissue and de-epithelialized grafts: a comparative randomized-controlled clinical trial. J Clin Periodontol. 2010;37(8):728–38. PubMed
Nevins M, Nevins ML, Kim SW, Schupbach P, Kim DM. The use of mucograft collagen matrix to augment the zone of keratinized tissue around teeth: a pilot study. Int J Periodontics Restorative Dent. 2011;31(4):367–73. PubMed
Vignoletti F, Nuñez J, Discepoli N, De Sanctis F, Caffesse R, Muñoz F, et al. Clinical and histological healing of a new collagen matrix in combination with the coronally advanced flap for the treatment of Miller class-I recession defects: an experimental study in the minipig. J Clin Periodontol. 2011;38(9):847–55. CrossRefPubMed
Sanz M, Lorenzo R, Aranda JJ, Martin C, Orsini M. Clinical evaluation of a new collagen matrix (Mucograft prototype) to enhance the width of keratinized tissue in patients with fixed prosthetic restorations: a randomized prospective clinical trial. J Clin Periodontol. 2009;36(10):868–76. CrossRefPubMed
Mankoski A. Mankoski Pain Scale, copyright 1995. 1996.
Petrauskaite O, PDS G, Fernandes MH, Juodzbaylys G, Stumbras A, Maminskas J, Cicciù M. Biomimetic mineralization on a macroporous cellulose-based matrix for bone regeneration. Biomed Res Int. 2013;2013:452750.
Harris RJ. Gingival augmentation with an acellular dermal matrix: human histologic evaluation of a case—placement of the graft on bone. Int J Periodontics Restorative Dent. 2001;21(1):69–75. PubMed
Harris RJ. Gingival augmentation with an acellular dermal matrix: human histologic evaluation of a case—placement of the graft on periosteum. Int J Periodontics Restorative Dent. 2004;24(4):378–85. PubMed
Rotundo R, Pini-Prato G. Use of a new collagen matrix (mucograft) for the treatment of multiple gingival recessions: case reports. Int J Periodontics Restorative Dent. 2012;32(4):413–9. PubMed
Laino L, Troiano G, Menditti D, Herford AS, Lucchese A, Cervino G, Lauritano F, Serpico R, Cicciù M. Use of collagen matrix to improve wound repair after mucosal biopsy: a multicenter case series. Int J Clin Exp Med. 2017;10(5):8363–8.
Schmitt CM, Moest T, Lutz R, Wehrhan F, Neukam FW, Schlegel KA. Long-term outcomes after vestibuloplasty with a porcine collagen matrix (Mucograft®) versus the free gingival graft: a comparative prospective clinical trial. Clin Oral Impl Res. 2016;27:e125–33. CrossRef
- The efficacy of a porcine collagen matrix in keratinized tissue augmentation: a 5-year follow-up study
G. B. Grossi
A. S. Herford
- Springer Berlin Heidelberg
Neu im Fachgebiet Zahnmedizin
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