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Current Allergy and Asthma Reports

Erschienen in:

01.01.2018 | Food Allergy (T Green, Section Editor)

The Genetics of Food Allergy

verfasst von: Cristina A. Carter, Pamela A. Frischmeyer-Guerrerio

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 1/2018

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Abstract

Purpose of Review

Food allergy likely arises from a complex interplay between environmental triggers and genetic susceptibility. Here, we review recent studies that have investigated the genetic pathways and mechanisms that may contribute to the pathogenesis of food allergy.

Recent Findings

A heritability component of food allergy has been observed in multiple studies. A number of monogenic diseases characterized by food allergy have elucidated pathways that may be important in pathogenesis. Several population-based genetic variants associated with food allergy have also been identified.

Summary

The genetic mechanisms that play a role in the development of food allergy are heterogeneous and complex. Advances in our understanding of the genetics of food allergy, and how this predisposition interacts with environmental exposures to lead to disease, will improve our understanding of the key pathways leading to food allergy and inform more effective prevention and treatment strategies.

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Titel: The Genetics of Food Allergy
verfasst von: Cristina A. Carter
Pamela A. Frischmeyer-Guerrerio
Publikationsdatum: 01.01.2018
Verlag: Springer US
Erschienen in: Current Allergy and Asthma Reports / Ausgabe 1/2018
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI: https://doi.org/10.1007/s11882-018-0756-z

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The Genetics of Food Allergy