Skip to main content
main-content

05.02.2018 | Original Contributions | Ausgabe 7/2018

Obesity Surgery 7/2018

The Impact of Bariatric Surgery on Short Term Risk of Clostridium Difficile Admissions

Zeitschrift:
Obesity Surgery > Ausgabe 7/2018
Autoren:
Hisham Hussan, Emmanuel Ugbarugba, Michael T. Bailey, Kyle Porter, Bradley Needleman, Sabrena Noria, Benjamin O’Donnell, Steven K. Clinton
Wichtige Hinweise

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s11695-018-3131-1) contains supplementary material, which is available to authorized users.
AWARD:
This research was presented as an oral at the American College of Gastroenterology (ACG) 2016 National Meeting and awarded the 2016 ACG Obesity Award for Best Scientific Paper.

Grant Support:

No financial support was utilized in the creation of this project.

Abstract

Background and Aims

Clostridium difficile infection (CDI) is major health care concern with reports linking it to obesity. Our aim was to investigate the little known impact of the two most common bariatric surgeries, Roux-en-Y gastric bypass (RYGB) and vertical sleeve gastrectomy (VSG), on risk of CDI admissions.

Methods

This is a retrospective cohort study using the 2013 Nationwide Readmission Database. We examined inpatient CDI rates within 120 days after RYGB (n = 40,059) and VSG (n = 45,394). In a time to event analysis we also evaluated inpatient CDI rates up to 11 months post-surgery. We chose morbidly obese patients that underwent non-emergent ventral hernia repair (VHR) as additional surgical controls (n = 9673).

Result

CDI rates were higher after RYGB than VSG in the first 30 days (odds ratio [OR] = 2.10; 95% confidence interval [CI], 1.05–4.20) with a similar but nonsignificant trend within 31–120 days. CDI rates were also higher after RYGB compared to VHR controls within 31–120 days after surgery (OR = 3.22, 95%CI: 1.31, 7.88, p = 0.01). In a time to event analysis with up to 11 months follow up, RYGB led to higher CDI compared to VSG (hazard ratio [HR] = 1.87; 95% CI, 1.12–3.13) with a trend towards higher CDI compared to VHR (HR = 1.95; 95% CI, 0.94–4.06). Similar CDI rates occurred after VSG vs VHR.

Conclusions

RYGB may increase the risk of CDI hospitalization when compared to VSG and VHR controls. This data suggest VSG may be a better bariatric choice when post-surgical CDI risk is a concern.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Weitere Produktempfehlungen anzeigen
Zusatzmaterial
ESM 1 (DOCX 96 kb)
11695_2018_3131_MOESM1_ESM.docx
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 7/2018

Obesity Surgery 7/2018 Zur Ausgabe
  1. Das kostenlose Testabonnement läuft nach 14 Tagen automatisch und formlos aus. Dieses Abonnement kann nur einmal getestet werden.

Neu im Fachgebiet Chirurgie

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Chirurgie und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise