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01.10.2005 | Original Contribution

The Impact of Diagnosis and Treatment of Rectal Cancer on Paid and Unpaid Labor

verfasst von: Mandy van den Brink, M.Sc., Wilbert B. van den Hout, Ph.D., Job Kievit, M.D., Ph.D., Corrie A. M. Marijnen, M.D., Ph.D., Hein Putter, Ph.D., Cornelis J. H. van de Velde, M.D., Ph.D., Anne M. Stiggelbout, Ph.D.

Erschienen in: Diseases of the Colon & Rectum | Ausgabe 10/2005

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PURPOSE

This study was designed to describe the consequences of diagnosis and treatment of rectal cancer for paid and unpaid labor over time and to identify sociodemographic-related factors, treatment-related factors, and quality of life-related factors associated with paid and unpaid labor.

METHODS

Data were assessed prospectively in two samples of patients with primary rectal cancer, participating in a multicenter clinical trial, who were randomized to receive surgery with or without 5 × 5-Gy preoperative radiotherapy. For paid labor, 292 patients who indicated paid labor before treatment filled out quality of life questionnaires, which included questions on paid labor at 3, 6, 12, 18, and 24 months after surgery. For unpaid labor, another sample of 92 patients also filled out the Health and Labor questionnaire, which included questions on unpaid labor, before treatment, and at 3 and 12 months after treatment.

RESULTS

From 3 to 18 months after surgery, paid labor resumption increased from 19 to 63 percent (P < 0.001). At 24 months after surgery, paid labor resumption was 61 percent. In a multivariate analysis, age older than 55 years (P ≤ 0.001), lower education level (P ≤ 0.003), shorter time since surgery (P < 0.001), preoperative radiotherapy (P = 0.02), lower valuation of overall health (P < 0.01), more physical symptom distress (P < 0.001), and more limitations in daily activities (P < 0.001) were all associated with less or later resumption of paid labor. The average amount of unpaid labor increased from 17.3 hours per week at 3 months to 21 hours per week at 12 months after surgery. In a multivariate analysis, only shorter time since surgery (P = 0.03) and male gender (P < 0.001) were related to less unpaid labor.

CONCLUSIONS

Diagnosis and treatment of rectal cancer affect paid and unpaid labor. The impact on paid labor is most pronounced. Multiple other sociodemographic and quality of life-related variables also were associated with paid labor. Patient information and decision making on preoperative radiotherapy should include the effects on paid labor, and interventions focused on promoting paid labor participation in patients with rectal cancer should be tailored to the specific characteristics and needs of those patients.
Literatur
1.
Zurück zum Zitat Eindhoven Cancer Registry. Cancer incidence and survival in the Southeast of the Netherlands 1955–1994. Eindhoven, the Netherlands: Comprehensive Cancer Center South, 1995 Eindhoven Cancer Registry. Cancer incidence and survival in the Southeast of the Netherlands 1955–1994. Eindhoven, the Netherlands: Comprehensive Cancer Center South, 1995
2.
Zurück zum Zitat Netherlands Cancer Registry. Trends of cancer in the Netherlands 1989–1998. Utrecht, the Netherlands: Association of Comprehensive Cancer Centres, 2002 Netherlands Cancer Registry. Trends of cancer in the Netherlands 1989–1998. Utrecht, the Netherlands: Association of Comprehensive Cancer Centres, 2002
3.
Zurück zum Zitat Spelten, ER, Sprangers, MA, Verbeek, JH 2002Factors reported to influence the return to work of cancer survivors: a literature reviewPsychooncology1112431CrossRefPubMed Spelten, ER, Sprangers, MA, Verbeek, JH 2002Factors reported to influence the return to work of cancer survivors: a literature reviewPsychooncology1112431CrossRefPubMed
4.
Zurück zum Zitat Fobair, P, Hoppe, RT, Bloom, J, Cox, R, Varghese, A, Spiegel, D 1986Psychosocial problems among survivors of Hodgkin's diseaseJ Clin Oncol480514PubMed Fobair, P, Hoppe, RT, Bloom, J, Cox, R, Varghese, A, Spiegel, D 1986Psychosocial problems among survivors of Hodgkin's diseaseJ Clin Oncol480514PubMed
5.
Zurück zum Zitat van den Hout, WB, van den Brink, M, Stiggelbout, AM, Velde, CJ, Kievit, J 2002Cost-effectiveness analysis of colorectal cancer treatmentsEur J Cancer3895363CrossRefPubMed van den Hout, WB, van den Brink, M, Stiggelbout, AM, Velde, CJ, Kievit, J 2002Cost-effectiveness analysis of colorectal cancer treatmentsEur J Cancer3895363CrossRefPubMed
6.
Zurück zum Zitat Hawrylshyn, O 1977Towards a definition of non-market activitiesThe Review of Income and Wealth237996CrossRef Hawrylshyn, O 1977Towards a definition of non-market activitiesThe Review of Income and Wealth237996CrossRef
7.
Zurück zum Zitat Wiggers, T, Vries, MR, Veeze-Kuypers, B 1996Surgery for local recurrence of rectal carcinomaDis Colon Rectum393238CrossRefPubMed Wiggers, T, Vries, MR, Veeze-Kuypers, B 1996Surgery for local recurrence of rectal carcinomaDis Colon Rectum393238CrossRefPubMed
8.
Zurück zum Zitat Enker, WE 1992Potency, cure, and local control in the operative treatment of rectal cancerArch Surg1271396401PubMed Enker, WE 1992Potency, cure, and local control in the operative treatment of rectal cancerArch Surg1271396401PubMed
9.
Zurück zum Zitat Heald, RJ, Karanjia, ND 1992Results of radical surgery for rectal cancerWorld J Surg1684857CrossRefPubMed Heald, RJ, Karanjia, ND 1992Results of radical surgery for rectal cancerWorld J Surg1684857CrossRefPubMed
10.
Zurück zum Zitat Harnsberger, JR, Vernava, VM, Longo, WE 1994Radical abdominopelvic lymphadenectomy: historic perspective and current role in the surgical management of rectal cancerDis Colon Rectum377387CrossRefPubMed Harnsberger, JR, Vernava, VM, Longo, WE 1994Radical abdominopelvic lymphadenectomy: historic perspective and current role in the surgical management of rectal cancerDis Colon Rectum377387CrossRefPubMed
11.
Zurück zum Zitat Kapiteijn, E, Marijnen, CA, Colenbrander, AC, et al. 1998Local recurrence in patients with rectal cancer diagnosed between 1988 and 1992: a population-based study in the west NetherlandsEur J Surg Oncol2452835CrossRefPubMed Kapiteijn, E, Marijnen, CA, Colenbrander, AC,  et al. 1998Local recurrence in patients with rectal cancer diagnosed between 1988 and 1992: a population-based study in the west NetherlandsEur J Surg Oncol2452835CrossRefPubMed
12.
Zurück zum Zitat Phillips, RK, Hittinger, R, Blesovsky, L, Fry, JS, Fielding, LP 1984Local recurrence following ‘curative’ surgery for large bowel cancer: I. The overall pictureBr J Surg71126PubMed Phillips, RK, Hittinger, R, Blesovsky, L, Fry, JS, Fielding, LP 1984Local recurrence following ‘curative’ surgery for large bowel cancer: I. The overall pictureBr J Surg71126PubMed
13.
Zurück zum Zitat Martijn, H, Voogd, AC, Poll-Franse, LV, Repelaer van Driel, OJ, Rutten, HJ, Coebergh, JW 2003Improved survival of patients with rectal cancer since 1980: a population-based studyEur J Cancer3920739CrossRefPubMed Martijn, H, Voogd, AC, Poll-Franse, LV, Repelaer van Driel, OJ, Rutten, HJ, Coebergh, JW 2003Improved survival of patients with rectal cancer since 1980: a population-based studyEur J Cancer3920739CrossRefPubMed
14.
Zurück zum Zitat Kapiteijn, E, Marijnen, CA, Nagtegaal, ID, et al. 2001Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancerN Engl J Med34563846PubMed Kapiteijn, E, Marijnen, CA, Nagtegaal, ID,  et al. 2001Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancerN Engl J Med34563846PubMed
15.
Zurück zum Zitat Stockholm Rectal Cancer Study Group. Preoperative short-term radiation therapy in operable rectal carcinoma. A prospective randomized trial. Cancer 1990;66:49–55 Stockholm Rectal Cancer Study Group. Preoperative short-term radiation therapy in operable rectal carcinoma. A prospective randomized trial. Cancer 1990;66:49–55
16.
Zurück zum Zitat Stockholm Colorectal Cancer Study Group. Randomized study on preoperative radiotherapy in rectal carcinoma. Ann Surg Oncol 1996;3:423–30 Stockholm Colorectal Cancer Study Group. Randomized study on preoperative radiotherapy in rectal carcinoma. Ann Surg Oncol 1996;3:423–30
17.
Zurück zum Zitat Swedish Rectal Cancer Trial. Initial report from a Swedish multicentre study examining the role of preoperative irradiation in the treatment of patients with resectable rectal carcinoma. Br J Surg 1993; 80: 1333–6 Swedish Rectal Cancer Trial. Initial report from a Swedish multicentre study examining the role of preoperative irradiation in the treatment of patients with resectable rectal carcinoma. Br J Surg 1993; 80: 1333–6
18.
Zurück zum Zitat Goldberg, PA, Nicholls, RJ, Porter, NH, Love, S, Grimsey, JE 1994Long-term results of a randomised trial of short-course low-dose adjuvant pre-operative radiotherapy for rectal cancer: reduction in local treatment failureEur J Cancer30A16026CrossRefPubMed Goldberg, PA, Nicholls, RJ, Porter, NH, Love, S, Grimsey, JE 1994Long-term results of a randomised trial of short-course low-dose adjuvant pre-operative radiotherapy for rectal cancer: reduction in local treatment failureEur J Cancer30A16026CrossRefPubMed
19.
Zurück zum Zitat Marijnen, CA, Kapiteijn, EK, Velde, CJ, et al. 2002Acute side effects and complications after short-term preoperative radiotherapy combined with total mesorectal excision in primary rectal cancer: report of a multicenter randomized trialJ Clin Oncol2081725CrossRefPubMed Marijnen, CA, Kapiteijn, EK, Velde, CJ,  et al. 2002Acute side effects and complications after short-term preoperative radiotherapy combined with total mesorectal excision in primary rectal cancer: report of a multicenter randomized trialJ Clin Oncol2081725CrossRefPubMed
20.
Zurück zum Zitat Holm, T, Singnomklao, T, Rutqvist, LE, Cedermark, B 1996Adjuvant preoperative radiotherapy in patients with rectal carcinoma. Adverse effects during long term follow-up of two randomized trialsCancer7896876CrossRefPubMed Holm, T, Singnomklao, T, Rutqvist, LE, Cedermark, B 1996Adjuvant preoperative radiotherapy in patients with rectal carcinoma. Adverse effects during long term follow-up of two randomized trialsCancer7896876CrossRefPubMed
21.
Zurück zum Zitat Pahlman, L, Glimelius, B 1990Pre- or postoperative radiotherapy in rectal and rectosigmoid carcinoma. Report from a randomized multicenter trialAnn Surg21118795PubMed Pahlman, L, Glimelius, B 1990Pre- or postoperative radiotherapy in rectal and rectosigmoid carcinoma. Report from a randomized multicenter trialAnn Surg21118795PubMed
22.
Zurück zum Zitat Camma, C, Giunta, M, Fiorica, F, Pagliaro, L, Craxi, A, Cottone, M 2000Preoperative radiotherapy for resectable rectal cancer: a meta-analysisJAMA284100815CrossRefPubMed Camma, C, Giunta, M, Fiorica, F, Pagliaro, L, Craxi, A, Cottone, M 2000Preoperative radiotherapy for resectable rectal cancer: a meta-analysisJAMA284100815CrossRefPubMed
23.
Zurück zum Zitat Colorectal Cancer Collaborative Group. Adjuvant radiotherapy for rectal cancer: a systematic overview of 8,507 patients from 22 randomised trials. Lancet 2001; 358: 1291–304. Colorectal Cancer Collaborative Group. Adjuvant radiotherapy for rectal cancer: a systematic overview of 8,507 patients from 22 randomised trials. Lancet 2001; 358: 1291–304.
24.
Zurück zum Zitat Cedermark, B, Johansson, H, Rutqvist, LE, Wilking, N 1995The Stockholm I trial of preoperative short term radiotherapy in operable rectal carcinoma. A prospective randomized trialCancer75226975PubMed Cedermark, B, Johansson, H, Rutqvist, LE, Wilking, N 1995The Stockholm I trial of preoperative short term radiotherapy in operable rectal carcinoma. A prospective randomized trialCancer75226975PubMed
25.
Zurück zum Zitat van den Brink, M, van den Hout, WB, Stiggelbout, AM, Klein Kranenbarg, E, Velde, CJ, Kievit, J 2004Cost-utility analysis of pre-operative radiotherapy in patients with rectal cancer undergoing total mesorectal excision: a study of the Dutch Colorectal Cancer GroupJ Clin Oncol2224453CrossRefPubMed van den Brink, M, van den Hout, WB, Stiggelbout, AM, Klein Kranenbarg, E, Velde, CJ, Kievit, J 2004Cost-utility analysis of pre-operative radiotherapy in patients with rectal cancer undergoing total mesorectal excision: a study of the Dutch Colorectal Cancer GroupJ Clin Oncol2224453CrossRefPubMed
26.
Zurück zum Zitat Roijen, L, Essink-Bot, M, Koopmanschap, MA, Michel, BC, Rutten, FF 1995Societal perspective on the burden of migraine in the NetherlandsPharmacoeconomics71709PubMed Roijen, L, Essink-Bot, M, Koopmanschap, MA, Michel, BC, Rutten, FF 1995Societal perspective on the burden of migraine in the NetherlandsPharmacoeconomics71709PubMed
27.
Zurück zum Zitat Roijen, L, Essink Bot, ML, Koopmanschap, MA, Bonsel, G, Rutten, FF 1996Labor and health status in economic evaluation of health care. The Health and Labor QuestionnaireInt J Technol Assess Health Care1240515PubMed Roijen, L, Essink Bot, ML, Koopmanschap, MA, Bonsel, G, Rutten, FF 1996Labor and health status in economic evaluation of health care. The Health and Labor QuestionnaireInt J Technol Assess Health Care1240515PubMed
28.
Zurück zum Zitat Haes, JC, Knippenberg, FC, Neijt, JP 1990Measuring psychological and physical distress in cancer patients: structure and application of the Rotterdam Symptom ChecklistBr J Cancer6210348PubMed Haes, JC, Knippenberg, FC, Neijt, JP 1990Measuring psychological and physical distress in cancer patients: structure and application of the Rotterdam Symptom ChecklistBr J Cancer6210348PubMed
29.
Zurück zum Zitat Uyl de Groot, CA, Rutten, FF, Bonsel, GJ 1994Measurement and valuation of quality of life in economic appraisal of cancer treatmentEur J Cancer30A1117PubMed Uyl de Groot, CA, Rutten, FF, Bonsel, GJ 1994Measurement and valuation of quality of life in economic appraisal of cancer treatmentEur J Cancer30A1117PubMed
30.
Zurück zum Zitat Putter H, Marijnen CA, Klein-Kranenbarg E, van de Velde CJ, Stiggelbout AM. Missing forms and dropout in the TME quality of life substudy. Qual Life Res 2005;14:857–65 Putter H, Marijnen CA, Klein-Kranenbarg E, van de Velde CJ, Stiggelbout AM. Missing forms and dropout in the TME quality of life substudy. Qual Life Res 2005;14:857–65
Metadaten
Titel
The Impact of Diagnosis and Treatment of Rectal Cancer on Paid and Unpaid Labor
verfasst von
Mandy van den Brink, M.Sc.
Wilbert B. van den Hout, Ph.D.
Job Kievit, M.D., Ph.D.
Corrie A. M. Marijnen, M.D., Ph.D.
Hein Putter, Ph.D.
Cornelis J. H. van de Velde, M.D., Ph.D.
Anne M. Stiggelbout, Ph.D.
Publikationsdatum
01.10.2005
Erschienen in
Diseases of the Colon & Rectum / Ausgabe 10/2005
Print ISSN: 0012-3706
Elektronische ISSN: 1530-0358
DOI
https://doi.org/10.1007/s10350-005-0120-y

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