Skip to main content
main-content

23.06.2018 | Bone and Joint Pain (T King and S Amin, Section Editors) | Ausgabe 4/2018 Open Access

Current Osteoporosis Reports 4/2018

The Impact of Exercise in Rodent Models of Chronic Pain

Zeitschrift:
Current Osteoporosis Reports > Ausgabe 4/2018
Autor:
Mark Henry Pitcher
Wichtige Hinweise
This article is part of the Topical Collection on Bone and Joint Pain

Abstract

Purpose of Review

Physical activity is increasingly recommended for chronic pain. In this review, we briefly survey recent, high-quality meta-analyses on the effects of exercise in human chronic pain populations, followed by a critical discussion of the rodent literature.

Recent Findings

Most meta-analytical studies on the effects of exercise in human chronic pain populations describe moderate improvements in various types of chronic pain, despite substantial variability in the outcomes reported in the primary literature. The most consistent findings suggest that while greater adherence to exercise programs produces better outcomes, there is minimal support for the superiority of one type of exercise over another. The rodent literature similarly suggests that while regular exercise reduces hypersensitivity in rodent models of chronic pain, exercise benefits do not appear to relate to either the type of injury or any particular facet of the exercise paradigm. Potential factors underlying these results are discussed, including the putative involvement of stress-induced analgesic effects associated with certain types of exercise paradigms.

Summary

Exercise research using rodent models of chronic pain would benefit from increased attention to the role of stress in exercise-induced analgesia, as well as the incorporation of more clinically relevant exercise paradigms.

Unsere Produktempfehlungen

e.Med Interdisziplinär

Kombi-Abonnement

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Premium-Inhalten der Fachzeitschriften, inklusive eines Print-Abos.

Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 4/2018

Current Osteoporosis Reports 4/2018Zur Ausgabe

Bone and Joint Pain (T King Deeny and S Amin, Section Editors)

New Insights in Understanding and Treating Bone Fracture Pain

Bone Marrow and Adipose Tissue (G Duque and B Lecka-Czernik, Section Editors)

Bone Marrow Adipose Tissue and Skeletal Health

Genetics (M Johnson and S Ralston, Section Editors)

Mouse Cre Models for the Study of Bone Diseases

Craniofacial Skeleton (WE Roberts, Section Editor)

Part I: Development and Physiology of the Temporomandibular Joint

Neu im Fachgebiet Orthopädie und Unfallchirurgie

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Orthopädie und Unfallchirurgie und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise