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Clinical Oral Investigations

Erschienen in:

10.11.2018 | Original Article

The improvement of biocompatibility of adhesives

The effects of resveratrol on biocompatibility and dentin micro-tensile bond strengths of self-etch adhesives

verfasst von: Cigdem Atalayin, Huseyin Tezel, Zeynep Ergucu, Nimet Unlu, Guliz Armagan, Taner Dagci, Timur Kose

Erschienen in: Clinical Oral Investigations | Ausgabe 8/2019

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Abstract

Objective

The aim of this in vitro study is to evaluate the effects of resveratrol (RES) addition on the cytotoxicity and microtensile bond strength (μTBS) of different adhesives.

Materials and methods

Five self-etching adhesives (G-aenial Bond-GC, Optibond All in One-Kerr, Gluma Self Etch-Kulzer, Clearfil S³ Bond-Kuraray, and Nova Compo-B Plus-Imicryl) were tested. They were applied to L-929 cell culture by the extract method. In the test groups, 0.5 μM RES (Sigma-Aldrich) was added into the medium. Cell viability was assessed by MTT assay after 24 h. Human extracted third molars were used for μTBS test (n = 7). The adhesives with or without 0.5 μM RES addition were applied on dentin surfaces. A composite build-up was constructed. Then, the specimens were sectioned into multiple beams with the non-trimming version of the microtensile test and subjected to microtensile forces. Statistical analysis was performed using ANOVA and post hoc Tukey test (p ˂ 0.05).

Results

The extracts of all adhesives decreased the cell viability. However, RES addition increased the cell viability in all groups (p ˂ 0.05). RES addition did not cause any decrease in μTBS values of the adhesives compared to baseline. Optibond All in One showed the highest μTBS after RES addition. It was followed by Clerafil S³ Bond and Nova Compo-B Plus. No difference was determined between the Optibond All in One and Clearfil S³ Bond. There was difference between Optibond All in One and Nova Compo-B Plus (p ˂ 0.05).

Conclusion

RES addition may improve the biocompatibility without causing negative influence on μTBS of the adhesives.

Clinical relevance

RES addition has clinical applicable potential to overcome the adverse biocompatibility of adhesives.

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Titel: The improvement of biocompatibility of adhesives
The effects of resveratrol on biocompatibility and dentin micro-tensile bond strengths of self-etch adhesives
verfasst von: Cigdem Atalayin
Huseyin Tezel
Zeynep Ergucu
Nimet Unlu
Guliz Armagan
Taner Dagci
Timur Kose
Publikationsdatum: 10.11.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Clinical Oral Investigations / Ausgabe 8/2019
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-018-2745-y

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The improvement of biocompatibility of adhesives

The effects of resveratrol on biocompatibility and dentin micro-tensile bond strengths of self-etch adhesives

Abstract

Objective

Materials and methods

Results

Conclusion

Clinical relevance

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Springer Medizin

Abstract

Objective

Materials and methods

Results

Conclusion

Clinical relevance

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