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International Ophthalmology

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14.10.2017 | Original Paper

The influence of mitomycin C concentration on the outcome of trabeculectomy in uveitic glaucoma

verfasst von: Faisal A. Almobarak, Ali H. Alharbi, Jose Morales, Ibrahim Aljadaan

Erschienen in: International Ophthalmology | Ausgabe 6/2018

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Abstract

Purpose

To evaluate the influence of mitomycin C (MMC) concentration on the outcome of trabeculectomy in uveitic glaucoma.

Methods

Retrospective comparative study included 50 patients who underwent MMC-enhanced trabeculectomy for uncontrolled uveitic glaucoma. Patients were divided into two groups based on the concentration of MMC used during trabeculectomy (high [0.04%] or low [0.02%]). The main outcome measures were: the intraocular pressure (IOP), the number of antiglaucoma medications, the need for further glaucoma surgeries, and trabeculectomy success.

Results

There were no differences in the IOP nor antiglaucoma medications. The success rates were 76.0 and 68.0%, while the failure rates were 24.0 and 32.0% in the 0.02 and 0.04% MMC groups, respectively.

Conclusion

Trabeculectomy augmented with low (0.02%) MMC concentration seems to have comparable outcomes in uveitic glaucoma compared with high (0.04%) concentration.

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Titel: The influence of mitomycin C concentration on the outcome of trabeculectomy in uveitic glaucoma
verfasst von: Faisal A. Almobarak
Ali H. Alharbi
Jose Morales
Ibrahim Aljadaan
Publikationsdatum: 14.10.2017
Verlag: Springer Netherlands
Erschienen in: International Ophthalmology / Ausgabe 6/2018
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-017-0737-6

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The influence of mitomycin C concentration on the outcome of trabeculectomy in uveitic glaucoma

Abstract

Purpose

Methods

Results

Conclusion

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Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

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