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01.09.2017 | Review

The intensive care delirium research agenda: a multinational, interprofessional perspective

verfasst von: Pratik P. Pandharipande, E. Wesley Ely, Rakesh C. Arora, Michele C. Balas, Malaz A. Boustani, Gabriel Heras La Calle, Colm Cunningham, John W. Devlin, Julius Elefante, Jin H. Han, Alasdair M. MacLullich, José R. Maldonado, Alessandro Morandi, Dale M. Needham, Valerie J. Page, Louise Rose, Jorge I. F. Salluh, Tarek Sharshar, Yahya Shehabi, Yoanna Skrobik, Arjen J. C. Slooter, Heidi A. B. Smith

Erschienen in: Intensive Care Medicine | Ausgabe 9/2017

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Abstract

Delirium, a prevalent organ dysfunction in critically ill patients, is independently associated with increased morbidity. This last decade has witnessed an exponential growth in delirium research in hospitalized patients, including those critically ill, and this research has highlighted that delirium needs to be better understood mechanistically to help foster research that will ultimately lead to its prevention and treatment. In this invited, evidence-based paper, a multinational and interprofessional group of clinicians and researchers from within the fields of critical care medicine, psychiatry, pediatrics, anesthesiology, geriatrics, surgery, neurology, nursing, pharmacy, and the neurosciences sought to address five questions: (1) What is the current standard of care in managing ICU delirium? (2) What have been the major recent advances in delirium research and care? (3) What are the common delirium beliefs that have been challenged by recent trials? (4) What are the remaining areas of uncertainty in delirium research? (5) What are some of the top study areas/trials to be done in the next 10 years? Herein, we briefly review the epidemiology of delirium, the current best practices for management of critically ill patients at risk for delirium or experiencing delirium, identify recent advances in our understanding of delirium as well as gaps in knowledge, and discuss research opportunities and barriers to implementation, with the goal of promoting an integrated research agenda.

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Titel: The intensive care delirium research agenda: a multinational, interprofessional perspective
verfasst von: Pratik P. Pandharipande
E. Wesley Ely
Rakesh C. Arora
Michele C. Balas
Malaz A. Boustani
Gabriel Heras La Calle
Colm Cunningham
John W. Devlin
Julius Elefante
Jin H. Han
Alasdair M. MacLullich
José R. Maldonado
Alessandro Morandi
Dale M. Needham
Valerie J. Page
Louise Rose
Jorge I. F. Salluh
Tarek Sharshar
Yahya Shehabi
Yoanna Skrobik
Arjen J. C. Slooter
Heidi A. B. Smith
Publikationsdatum: 01.09.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 9/2017
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-017-4860-7

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The intensive care delirium research agenda: a multinational, interprofessional perspective

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