nach oben

Archives of Gynecology and Obstetrics

Erschienen in:

27.12.2017 | Gynecologic Oncology

The morbidity of sexual dysfunction of 125 Chinese women following different types of radical hysterectomy for gynaecological malignancies

verfasst von: Xueqin Wang, Chunlin Chen, Ping Liu, Weili Li, Liling Wang, Yunlu Liu

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 2/2018

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Due to early detection and effective treatment, quality of sexual life of patients with gynaecological malignancies has become an important issue. However, the morbidity of sexual dysfunction and the proportion of different kinds of sexual dysfunction after radical hysterectomy are unclear. The aim of the current study was to assess the morbidity of sexual dysfunction and to conduct multivariate logistic regression analysis of patients’ sexual dysfunction.

Methods

Between July 2007 and December 2012, 125 women underwent radical hysterectomy, modified radical hysterectomy, and nerve-sparing radical hysterectomy were administered a self-reported sexual function questionnaire.

Results

The preoperative, and 1- and 2-year postoperative sexual dysfunction rates were 50.5% (50/99), 86.9% (93/107), and 92.3% (72/78), respectively. The incidence rates of sexual desire disorders before operation, at postoperative year 1, and at postoperative year 2 were 14.7% (14/95), 42.1% (45/107), and 51.9% (40/77), respectively. The preoperative incidence rates of sexual arousal disorders, orgasmic disorders, and sexual pain disorders were 18.4% (18/98), 51.1% (48/94), and 10.9% (11/101), respectively. At postoperative years 1 and 2, these were 38.8% (31/80), 81.0% (64/79), and 24.4% (20/82), and 49.1% (26/53), 84.6% (44/52), and 30.2% (16/53), respectively. Multivariable regression analysis revealed that age, preserved ovary, preserved posterior vaginal wall length, preoperative stage, radiotherapy, and education background were risk factors associated with sexual dysfunction.

Conclusion

The patients following radical hysterectomy had a high incidence of sexual dysfunction, which plateaued in postoperative years 1 and 2.

Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61(2):69–90. https://doi.org/10.3322/caac.20107 CrossRefPubMed

Eifel PJ, Winter K, Morris M, Levenback C, Grigsby PW, Cooper J, Rotman M, Gershenson D, Mutch DG (2004) Pelvic irradiation with concurrent chemotherapy versus pelvic and para-aortic irradiation for high-risk cervical cancer: an update of radiation therapy oncology group trial (RTOG) 90-01. J Clin Oncol 22(5):872–880. https://doi.org/10.1200/jco.2004.07.197 CrossRefPubMed

Peters WALP III, Barett RJ et al (2000) Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early stage cancer of the cervix. J Clin Oncol 18(8):1606–1613CrossRefPubMed

Ryu HS, Chun M, Chang KH, Chang HJ, Lee JP (2005) Postoperative adjuvant concurrent chemoradiotherapy improves survival rates for high-risk, early stage cervical cancer patients. Gynecol Oncol 96(2):490–495. https://doi.org/10.1016/j.ygyno.2004.10.038 CrossRefPubMed

Society AC (2011) Cancer facts and figures 2010. American Cancer Society, Atlanta

Vistad I, Fossa SD, Dahl AA (2006) A critical review of patient-rated quality of life studies of long-term survivors of cervical cancer. Gynecol Oncol 102(3):563–572. https://doi.org/10.1016/j.ygyno.2006.03.050 CrossRefPubMed

Pompili M, Innamorati M, Serafini G, Gonda X, Campi S, Rapinesi C, Giordano G, Montebovi F, Palermo M, Giupponi G, Tatarelli R, Biondi M, Amore M, Sher L, Rihmer Z, Girardi P (2012) How does subjective experience of pain relate to psychopathology among psychiatric patients? Gen Hosp Psychiatry 34(5):534–540. https://doi.org/10.1016/j.genhosppsych.2012.03.022 CrossRefPubMed

Cano A, Weisberg JN, Gallagher RM (2000) Marital satisfaction and pain severity mediate the association between negative spouse responses to pain and depressive symptoms in a chronic pain patient sample. Pain Med (Malden, Mass) 1(1):35–43. https://doi.org/10.1046/j.1526-4637.2000.99100.x CrossRef

Bergmark K, Avall-Lundqvist E, Dickman PW, Henningsohn L, Steineck G (1999) Vaginal changes and sexuality in women with a history of cervical cancer. N Engl J Med 340(18):1383–1389. https://doi.org/10.1056/nejm199905063401802 CrossRefPubMed

10.

Donovan KA, Taliaferro LA, Alvarez EM, Jacobsen PB, Roetzheim RG, Wenham RM (2007) Sexual health in women treated for cervical cancer: characteristics and correlates. Gynecol Oncol 104(2):428–434. https://doi.org/10.1016/j.ygyno.2006.08.009 CrossRefPubMed

11.

Grumann M, Robertson R, Hacker NF, Sommer G (2001) Sexual functioning in patients following radical hysterectomy for stage IB cancer of the cervix. Int J Gynecol Cancer 11(5):372–380CrossRefPubMed

12.

Gallo-Silver L (2000) The sexual rehabilitation of persons with cancer. Cancer Pract 8(1):10–15CrossRefPubMed

13.

Pieterse QD, Maas CP, ter Kuile MM, Lowik M, van Eijkeren MA, Trimbos JB, Kenter GG (2006) An observational longitudinal study to evaluate miction, defecation, and sexual function after radical hysterectomy with pelvic lymphadenectomy for early-stage cervical cancer. Int J Gynecol Cancer 16(3):1119–1129. https://doi.org/10.1111/j.1525-1438.2006.00461.x CrossRefPubMed

14.

Pieterse QD, Ter Kuile MM, Deruiter MC, Trimbos JB, Kenter GG, Maas CP (2008) Vaginal blood flow after radical hysterectomy with and without nerve sparing. A preliminary report. Int J Gynecol Cancer 18(3):576–583. https://doi.org/10.1111/j.1525-1438.2007.01046.x CrossRefPubMed

15.

Aerts L, Enzlin P, Verhaeghe J, Poppe W, Vergote I, Amant F (2014) Long-term sexual functioning in women after surgical treatment of cervical cancer stages IA to IB: a prospective controlled study. Int J Gynecol Cancer 24(8):1527–1534. https://doi.org/10.1097/igc.0000000000000236 CrossRefPubMed

16.

Pieterse QD, Kenter GG, Maas CP, de Kroon CD, Creutzberg CL, Trimbos JB, Ter Kuile MM (2013) Self-reported sexual, bowel and bladder function in cervical cancer patients following different treatment modalities: longitudinal prospective cohort study. Int J Gynecol Cancer 23(9):1717–1725. https://doi.org/10.1097/IGC.0b013e3182a80a65 CrossRefPubMed

17.

Han Z, Gan Z, Han H, Chen J, Li K, Guan N (2014) Validity of the Chinese version of the brief index of sexual functioning for women with a new scoring algorithm and comparison of normative and recurrently depressed Han Chinese population. J Sex Med 11(2):439–446. https://doi.org/10.1111/jsm.12385 CrossRefPubMed

18.

Laumann EO, Paik A, Rosen RC (1999) Sexual dysfunction in the United States: prevalence and predictors. JAMA 281(6):537–544CrossRefPubMed

19.

Salonia A, Munarriz RM, Naspro R, Nappi RE, Briganti A, Chionna R, Federghini F, Mirone V, Rigatti P, Goldstein I, Montorsi F (2004) Women’s sexual dysfunction: a pathophysiological review. BJU Int 93(8):1156–1164. https://doi.org/10.1111/j.1464-410X.2004.04796.x CrossRefPubMed

20.

Tangjitgamol S, Manusirivithaya S, Hanprasertpong J, Kasemsarn P, Soonthornthum T, Leelahakorn S, Thawaramara T, Lapcharoen O (2007) Sexual dysfunction in Thai women with early-stage cervical cancer after radical hysterectomy. Int J Gynecol Cancer 17(5):1104–1112. https://doi.org/10.1111/j.1525-1438.2007.00907.x CrossRefPubMed

21.

Dennerstein L, Lehert P (2004) Women’s sexual functioning, lifestyle, mid-age, and menopause in 12 European countries. Menopause (New York, NY) 11(6 Pt 2):778–785CrossRef

22.

Carter J, Sonoda Y, Baser RE, Raviv L, Chi DS, Barakat RR, Iasonos A, Brown CL, Abu-Rustum NR (2010) A 2-year prospective study assessing the emotional, sexual, and quality of life concerns of women undergoing radical trachelectomy versus radical hysterectomy for treatment of early-stage cervical cancer. Gynecol Oncol 119(2):358–365. https://doi.org/10.1016/j.ygyno.2010.07.016 CrossRefPubMedPubMedCentral

23.

Sarrel PM (1998) Ovarian hormones and vaginal blood flow: using laser Doppler velocimetry to measure effects in a clinical trial of post-menopausal women. Int J Impot Res 10(Suppl 2):S91–S93 (discussion S98–S101) PubMed

24.

Echeverry MC, Arango A, Castro B, Raigosa G (2010) Study of the prevalence of female sexual dysfunction in sexually active women 18 to 40 years of age in Medellin, Colombia. J Sex Med 7(8):2663–2669. https://doi.org/10.1111/j.1743-6109.2009.01695.x CrossRefPubMed

25.

Cibula D, Velechovska P, Slama J, Fischerova D, Pinkavova I, Pavlista D, Dundr P, Hill M, Freitag P, Zikan M (2010) Late morbidity following nerve-sparing radical hysterectomy. Gynecol Oncol 116(3):506–511. https://doi.org/10.1016/j.ygyno.2009.10.061 CrossRefPubMed

26.

Plotti F, Nelaj E, Sansone M, Antonelli E, Altavilla T, Angioli R, Benedetti Panici P (2012) Sexual function after modified radical hysterectomy (Piver II/Type B) vs. classic radical hysterectomy (Piver III/Type C2) for early stage cervical cancer. A prospective study. J Sex Med 9(3):909–917. https://doi.org/10.1111/j.1743-6109.2011.02581.x CrossRefPubMed

27.

Amsterdam A, Krychman ML (2006) Sexual dysfunction in patients with gynecologic neoplasms: a retrospective pilot study. J Sex Med 3(4):646–649. https://doi.org/10.1111/j.1743-6109.2006.00204.x CrossRefPubMed

28.

Zhou W, Yang X, Dai Y, Wu Q, He G, Yin G (2016) Survey of cervical cancer survivors regarding quality of life and sexual function. J Cancer Res Ther 12(2):938–944. https://doi.org/10.4103/0973-1482.175427 CrossRefPubMed

Titel: The morbidity of sexual dysfunction of 125 Chinese women following different types of radical hysterectomy for gynaecological malignancies
verfasst von: Xueqin Wang
Chunlin Chen
Ping Liu
Weili Li
Liling Wang
Yunlu Liu
Publikationsdatum: 27.12.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Archives of Gynecology and Obstetrics / Ausgabe 2/2018
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-017-4625-0

Neu im Fachgebiet Gynäkologie und Geburtshilfe

23.04.2024 | Medikamente in Schwangerschaft und Stillzeit | Nachrichten

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.

Newsletter bestellen

Springer Medizin

The morbidity of sexual dysfunction of 125 Chinese women following different types of radical hysterectomy for gynaecological malignancies

Abstract

Purpose

Methods

Results

Conclusion

Neu im Fachgebiet Gynäkologie und Geburtshilfe

ICI-Therapie in der Schwangerschaft wird gut toleriert

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

Bei RSV-Impfung vor 60. Lebensjahr über Off-Label-Gebrauch aufklären!

Harnwegsinfektprophylaxe: Es geht auch ohne Antibiotika

Update Gynäkologie

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2018

Effect of intramural fibroid on uterine and endometrial vascularity in infertile women scheduled for in-vitro fertilization

The role of serum ADAMTS-1 and aggrecan on polycystic ovary syndrome in adolescents and younger-aged females

Stimulation of chemokines in human endometrial stromal cells by tumor necrosis factor-α and interferon-γ is similar under apoptotic and non-apoptotic conditions

Vacuum extraction in low birth weight (< 2500 g) neonates

Failed manual removal of the placenta after vaginal delivery

MicroRNA-21 promotes proliferation, migration, and invasion of cervical cancer through targeting TIMP3

Neu im Fachgebiet Gynäkologie und Geburtshilfe

ICI-Therapie in der Schwangerschaft wird gut toleriert

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

Bei RSV-Impfung vor 60. Lebensjahr über Off-Label-Gebrauch aufklären!

Harnwegsinfektprophylaxe: Es geht auch ohne Antibiotika

Update Gynäkologie