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Erschienen in: Journal of Assisted Reproduction and Genetics 2/2018

02.03.2018 | Editor's Commentary

The non-cell autonomy of human gametes

verfasst von: David F. Albertini

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 2/2018

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Excerpt

Despite our efforts as taskmasters, we continue to search for that perfect pair of gametes to recombine on the hopeful way to embryo transfer; the outcome inadequacies of such searches remain poor in clinical terms. As ARTs evolved, the notion that gamete developmental proficiency would be evident in intrinsic morphological appearances or other extragametic (read niche) biomarkers of said gamete’s potential as embryo generators has settled deeply into the mindset of contemporary ART practitioners. …
Literatur
1.
Zurück zum Zitat Martin-DeLeon PA. Epididymosomes: transfer of fertility-modulating proteins to the sperm surface. Asian J Androl. 2015;17(5):720–5.PubMedPubMedCentral Martin-DeLeon PA. Epididymosomes: transfer of fertility-modulating proteins to the sperm surface. Asian J Androl. 2015;17(5):720–5.PubMedPubMedCentral
3.
Zurück zum Zitat Sullivan R. Epididymosomes: role of extracellular microvesicles in sperm maturation. Front Biosci (Schol Ed). 2016;8:106–14.CrossRef Sullivan R. Epididymosomes: role of extracellular microvesicles in sperm maturation. Front Biosci (Schol Ed). 2016;8:106–14.CrossRef
4.
Zurück zum Zitat Reilly JN, McLaughlin EA, Stanger SJ, Anderson AL, Hutcheon K, Church K, et al. Characterisation of mouse epididymosomes reveals a complex profile of microRNAs and a potential mechanism for modification of the sperm epigenome. Sci Rep. 2016;6:31794.CrossRefPubMedPubMedCentral Reilly JN, McLaughlin EA, Stanger SJ, Anderson AL, Hutcheon K, Church K, et al. Characterisation of mouse epididymosomes reveals a complex profile of microRNAs and a potential mechanism for modification of the sperm epigenome. Sci Rep. 2016;6:31794.CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat Murta D, Batista M, Silva E, Trindade A, Henrique D, Duarte A, et al. Notch signaling in the epididymal epithelium regulates sperm motility and is transferred at a distance within epididymosomes. Andrology. 2016;4(2):314–27.CrossRefPubMed Murta D, Batista M, Silva E, Trindade A, Henrique D, Duarte A, et al. Notch signaling in the epididymal epithelium regulates sperm motility and is transferred at a distance within epididymosomes. Andrology. 2016;4(2):314–27.CrossRefPubMed
6.
Zurück zum Zitat Sun L, Li D, Song K, Wei J, Yao S, Li Z, et al. Exosomes derived from human umbilical cord mesenchymal stem cells protect against cisplatin-induced ovarian granulosa cell stress and apoptosis in vitro. Sci Rep. 2017;7(1):2552.CrossRefPubMedPubMedCentral Sun L, Li D, Song K, Wei J, Yao S, Li Z, et al. Exosomes derived from human umbilical cord mesenchymal stem cells protect against cisplatin-induced ovarian granulosa cell stress and apoptosis in vitro. Sci Rep. 2017;7(1):2552.CrossRefPubMedPubMedCentral
7.
Zurück zum Zitat Salamonsen LA, Evans J, Nguyen HP, Edgell TA. The microenvironment of human implantation: determinant of reproductive success. Am J Reprod Immunol. 2016;75(3):218–25.CrossRefPubMed Salamonsen LA, Evans J, Nguyen HP, Edgell TA. The microenvironment of human implantation: determinant of reproductive success. Am J Reprod Immunol. 2016;75(3):218–25.CrossRefPubMed
8.
Metadaten
Titel
The non-cell autonomy of human gametes
verfasst von
David F. Albertini
Publikationsdatum
02.03.2018
Verlag
Springer US
Erschienen in
Journal of Assisted Reproduction and Genetics / Ausgabe 2/2018
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-018-1139-z

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