Erschienen in:
01.12.2007 | Short communication
The origins of oestrogen receptor negative breast cancer
verfasst von:
D Craig Allred
Erschienen in:
Breast Cancer Research
|
Sonderheft 2/2007
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Excerpt
Human invasive breast cancers (IBCs) are categorized in many ways, including on the basis of whether the tumour cells express oestrogen receptor (ER)-α. ER status is important clinically because ER mediates the growth-stimulating effects of circulating oestrogen and because tumours expressing ER have a significant chance of responding to hormonal therapies such as tamoxifen and aromatase inhibitors [
1]. …