Introduction
The outcomes of PEEK cages
Author, year | Study design | Surgical indications | Patients | PEEK cage type | Mean follow-up |
---|---|---|---|---|---|
Cho et al., 2002 | Prospective CS | Radiculopathy Myelopathy Radiculomyelopathy | 22 one-level 10 two-level 8 three-level | Filled with autograft | 6 months |
Liao et al., 2008 | Case Series | Radiculopathy Myelopathy Radiculomyelopathy | 19 Number of levels not specified. | Filled with allograft | 12 to 18 months (mean not reported) |
Lied et al., 2010 | Prospective CS | Radiculopathy Myelopathy Radiculomyelopathy No radiculopathy or myelopathy | 77 Number of levels not specific per study group. | Empty | 6 months |
Niu et al., 2010 | RCT | Radiculopathy Myelopathy Radiculomyelopathy | 16 one-level 9 two-level | Filled with allograft | 12 months |
Zhou et al., 2011 | Prospective CS | Radiculopathy Myelopathy | 30 one-level 17 two-level | Filled with autograft | 12 months |
Cabraja et al., 2012 | Retrospective CS | Radiculopathy Myelopathy | 42 one-level | Empty | 28.4 months |
Klingler et al., 2014 | Retrospective CS | Radiculopathy Myelopathy | 27 one-level 12 two-level | Empty | 16 months |
Shiban et al., 2015 | Case series | Radiculopathy Myelopathy | 127 one-level 125 two-level 13 three-level | Empty | 21 months |
Gok et al., 2016 | Case series | Radiculopathy | 25 one-level | Empty | 16 months |
Park et al., 2016 | Case series | Radiculopathy Myelopathy Radiculomyelopathy | 77 one-level | Empty | 21 months for subsidence patients 16 months for non-subsidence patients |
Farrokhi et al., 2017 | RCT | Radiculopathy Myelopathy Radiculomyelopathy | 32 one-level | Filled with bone substitute | 12 months |
Ofluoglu et al., 2017 | Case series | Radiculopathy Myelopathy | 16, no level specified | Filled with with ß-TCP | 13 months |
Suess et al., 2017 | RCT | Radiculopathy Myelopathy | 239 one-level | Empty | 18 months |
Kapetanakis et al., 2018 | Case series | Radiculopathy | 36 one-level | Empty | 12 months |
Godlewski et al, 2018 | Case series | Non-specific | 100 one- or multi-level | Filled with phosphocalcic hydroxyapatite | 12 months |
Kim et al., 2018 | Case series | Radiculopathy Myelopathy | 60 two-level 8 three-level | Empty | 27.6 months |
Fusion and subsidence rates
Author, year | Type of PEEK cage | Fusion rate | Subsidence rate | Mean follow-up |
---|---|---|---|---|
Cho et al., 2002 | Filled with autograft | 100% | 0% | 6 months |
Liao et al., 2008 | Filled with allograft | 100% | 0% | Range: 12–18 months |
Niu et al., 2010 | Filled with allograft | 100% | 0% | 12 months |
Zhou et al., 2011 | Filled with autograft | 100% | - | 12 months |
Cabraja et al., 2012 | Empty PEEK cages | 88.1% | 14.3% | 28.4 months |
Klingler et al., 2014 | Empty PEEK cages | 65% | 31% | 16 months |
Shiban et al., 2015 | Empty PEEK cages | 85% in one-level 95% in two-levels 94% in three-levels | 25% in one-level 27% in two-levels 15% in three-levels | 21 months |
Gok et al., 2016 | Empty PEEK cages | 92.3% | 33.8% | 16 months |
Park et al., 2016 | Empty PEEK cages | 92% | 12% | 12 months |
Farrokhi et al., 2017 | Filled with bone substitute | 93.8% | - | 12 months |
Kapetanakis et al., 2017 | Empty PEEK cages | 100% | 0% | 12 months |
Ofluoglu et al., 2017 | Filled with with ß-TCP | 95% | - | 13 months |
Suess et al., 2017 | Empty PEEK cages | 83% | - | 18 months |
Godlewski et al, 2018 | Filled with phosphocalcic hydroxyapatite | - | 10.23 | 12 months |
Kim et al., 2018 | Empty PEEK cages | 81.3% | 48.3% | 27.6 months |
Clinical outcomes
Author, year | VAS for neck pain | VAS for arm pain | Neck disability index | Odom’s criteria | JOA score | Modified JOA score |
---|---|---|---|---|---|---|
Niu et al., 2010 | X | |||||
Liao et al., 2008 | X | |||||
Zhou et al., 2011 | X | |||||
Cabraja et al., 2012 | X | X | X | X | ||
Klingler et al., 2014 | X | X | X | |||
Shiban et al., 2015 | X | X | ||||
Gok et al., 2016 | X | X | X | |||
Park et al., 2016 | X | X | X | X | ||
Farrokhi et al., 2017 | X | |||||
Kapetanakis et al., 2017 | X | X | X | |||
Ofluoglu et al., 2017 | X | X | X | |||
Suess et al., 2017 | X | X | X | X | ||
Godlewski et al, 2018 | X | X | X | |||
Kim et al., 2018 | X | X | X | X |
Visual analogue scale
Neck disability index
Odom’s criteria
Japanese Orthopaedic Society (JOA) score
Complications
Complications | |
18 Adjacent segment diseases requiring revision surgeries 4 Pseudarthrosis requiring revision surgeries 3 Post-operative haematoma requiring evacuation 2 Transient hoarseness of voice 2 Adjacent segment disease requiring revision surgeries 1 Pharyngitis 1 Transient dysphagia 1 Neurologic deterioration |