The online version of this article (doi:10.1007/s00705-016-3102-6) contains supplementary material, which is available to authorized users.
Z. Dian and M. Fan contribute to the article equally.
The aim of this study was to determine the prevalence of rotavirus A (RVA) infections in children from Kunming, China, and the RVA genotypes present. A total of 16,311 children with acute gastroenteritis were recruited for the study, and 33.1 % (5,394/16,311) were RVA positive. Children under 24 months of age were more susceptible to RVA infection, with an infection rate of 87.4 % (4,712/5,394). The most prevalent genotype was G9P (85/107, 79.4 %), which showed high sequence similarity to G9P strains from other regions of China and neighbouring countries, but not to the licensed vaccine strain LLR. These findings should be useful for the prevention of RVA infections.
Supplementary material 1 (DOC 708 kb)705_2016_3102_MOESM1_ESM.doc
Chen SC, Tan LB, Huang LM, Chen KT (2012) Rotavirus infection and the current status of rotavirus vaccines. J Formos Med Assoc 4:183–193
Duan ZJ, Liu N, Yang SH, Zhang J, Sun LW, Tang JY, Jin Y, Du ZQ, Xu J, Wu QB, Tong ZL, Gong ST, Qian Y, Ma JM, Liao XC, Widdowson MA, Jiang B, Fang ZY (2009) Hospital-based surveillance of rotavirus diarrhea in the People’s Republic of China, August 2003–July 2007. J Infect Dis 200(Suppl 1):S167–S173 CrossRefPubMed
Zhen Shuangping HY, Zongliu Hou (2006) Rotavirus molecular epidemic features in infants with enteritis in Kunming from 2002 to 2004. Chin J Pediatr 21(5):4
Wang YH, Pang BB, Ghosh S, Zhou X, Shintani T, Urushibara N, Song YW, He MY, Liu MQ, Tang WF, Peng JS, Hu Q, Zhou DJ, Kobayashi N (2014) Molecular epidemiology and genetic evolution of the whole genome of G3P human rotavirus in Wuhan, China, from 2000 through 2013. PLoS One 9(3):e88850 CrossRefPubMedPubMedCentral
Mullick S, Mandal P, Nayak MK, Ghosh S, De P, Rajendran K, Bhattacharya MK, Mitra U, Ramamurthy T, Kobayashi N, Chawla-Sarkar M (2014) Hospital based surveillance and genetic characterization of rotavirus strains in children (<5 years) with acute gastroenteritis in Kolkata, India, revealed resurgence of G9 and G2 genotypes during 2011–2013. Vaccine 32(Suppl 1):A20–A28 CrossRefPubMed
Wang X, Shi L, Qiao M, Wang Y, He M, Yong W, Du X, Guo B, Xie G, Xu Z, Ding J (2015) Phylogenetic Analyses and Characterization of the VP7 Genes of Serotype G9 Rotaviruses Circulating in Nanjing (China), 2012–2013. Bing du xue bao 31(4):425–432 PubMed
- The prevalence and genotype distribution of rotavirus A infection among children with acute gastroenteritis in Kunming, China
- Springer Vienna
Neu im Fachgebiet Innere Medizin
Meistgelesene Bücher aus der Inneren Medizin
e.Med Kampagnen-Visual, Mail Icon II