Erschienen in:
22.10.2020 | Original Article
The prevalence and risks of major comorbidities among inpatients with pulmonary tuberculosis in China from a gender and age perspective: a large-scale multicenter observational study
verfasst von:
Wanli Kang, Jian Du, Song Yang, Jiajia Yu, Hongyan Chen, Jianxiong Liu, Jinshan Ma, Mingwu Li, Jingmin Qin, Wei Shu, Peilan Zong, Yi Zhang, Yongkang Dong, Zhiyi Yang, Zaoxian Mei, Qunyi Deng, Pu Wang, Wenge Han, Meiying Wu, Ling Chen, Xinguo Zhao, Lei Tan, Fujian Li, Chao Zheng, Hongwei Liu, Xinjie Li, A. Ertai, Yingrong Du, Fenglin Liu, Wenyu Cui, Quanhong Wang, Xiaohong Chen, Junfeng Han, Qingyao Xie, Yanmei Feng, Wenyu Liu, Peijun Tang, Jianyong Zhang, Jian Zheng, Dawei Chen, Xiangyang Yao, Tong Ren, Yang Li, Yuanyuan Li, Lei Wu, Qiang Song, Mei Yang, Jian Zhang, Yuanyuan Liu, Shuliang Guo, Kun Yan, Xinghua Shen, Dan Lei, Yangli Zhang, Xiaofeng Yan, Liang Li, Shenjie Tang
Erschienen in:
European Journal of Clinical Microbiology & Infectious Diseases
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Ausgabe 4/2021
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Abstract
In clinical practice, PTB patients have concurrent many types of comorbidities such as pneumonia, liver disorder, diabetes mellitus, hematological disorder, and malnutrition. Detecting and treating specific comorbidities and preventing their development are important for PTB patients. However, the prevalence of most comorbid conditions in patients with PTB is not well described. We conducted a large-scale, multicenter, observational study to elucidate and illustrate the prevalence rates of major comorbidities in inpatients at 21 hospitals in China. The 19 specific comorbidities were selected for analysis in this patient cohort, and stratified the inpatient cohort according to age and gender. A total of 355,929 PTB inpatients were included, with a male:female ratio of 1.98 and the proportion of ≥ 65 years PTB inpatients was the most. Approximately 70% of PTB inpatients had at least one defined type of comorbidity. The prevalence of 19 specific comorbidities in inpatients with PTB was analyzed, with pneumonia being the most common comorbidity. The prevalence of most comorbidities was higher in males with PTB except thyroid disorders, mental health disorders, etc. The prevalence of defined most comorbidities in patients with PTB tended to increase with increasing age, although some specific comorbidities tended to increase initially then decrease with increasing age. Our study describes multiple clinically important comorbidities among PTB inpatients, and their prevalence between different gender and age groups. The results will enhance the clinical aptitude of physicians who treat patients with PTB to recognize, diagnose, and treat PTB comorbidities early.