Skip to main content
main-content

01.12.2019 | Research article | Ausgabe 1/2019 Open Access

BMC Psychiatry 1/2019

The prevalence, metabolic disturbances and clinical correlates of recent suicide attempts in Chinese inpatients with major depressive disorder

Zeitschrift:
BMC Psychiatry > Ausgabe 1/2019
Autoren:
Yue-Jiao Ma, Dong-Fang Wang, Ming Yuan, Xiao-Jie Zhang, Jiang Long, Shu-Bao Chen, Qiu-Xia Wu, Xu-Yi Wang, Marguerite Patel, Christopher D. Verrico, Tie-Qiao Liu, Xiang-Yang Zhang

Abstract

Background

Metabolic disturbances have been correlated with suicidality, but little is known about the association between suicide risk and metabolic disturbances among individuals with depression. This study was to evaluate the prevalence and clinical correlations, especially cardio-metabolic associated factors of recent suicide attempts in Chinese patients with major depressive disorder (MDD).

Methods

A total of 288 MDD inpatients were recruited. Their clinical and demographic data together with plasma glucose, lipid and thyroid function parameters were collected. Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS) and Eysenck Personality Questionnaire (EPQ) were rated for most of the patients.

Results

Of these MDD inpatients, 20.14% had attempted suicide during the past 1 month. Compared to those who had not attempted suicide, the suicide attempters had a significantly longer duration of illness, lower low-density lipoprotein (LDL) cholesterol, lower total cholesterol, and more psychotic symptoms. However, all these significant results did not survive after the bonferroni correction (all p > 0.05). A logistic regression analysis indicated that suicide attempts were associated with the lower total cholesterol and more psychotic symptoms.

Conclusions

Our findings support the hypothesis of the association of low plasma cholesterol level and recent suicidal attempts in patients with MDD.
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2019

BMC Psychiatry 1/2019 Zur Ausgabe

Neu im Fachgebiet Psychiatrie