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01.12.2015 | Research article | Ausgabe 1/2015 Open Access

BMC Public Health 1/2015

The Qatar Biobank: background and methods

Zeitschrift:
BMC Public Health > Ausgabe 1/2015
Autoren:
Hanan Al Kuwari, Asma Al Thani, Ajayeb Al Marri, Abdulla Al Kaabi, Hadi Abderrahim, Nahla Afifi, Fatima Qafoud, Queenie Chan, Ioanna Tzoulaki, Paul Downey, Heather Ward, Neil Murphy, Elio Riboli, Paul Elliott
Wichtige Hinweise

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

HAK, AAT, AAM, AAK contributed to the overall concept, design and oversight of the study; HA, NA and FQ contributed to study management, quality control and acquisition of data; QC, IT, HW, and NM performed the statistical analysis and contributed to interpretation of the data and drafting of the manuscript; PD contributed to development and scientific review of study protocols; ER and PE contributed to the design of the study, development of study protocols, study oversight, and drafted and revised the paper. All authors read and approved the final manuscript for submission.

Abstract

Background

The Qatar Biobank aims to collect extensive lifestyle, clinical, and biological information from up to 60,000 men and women Qatari nationals and long-term residents (individuals living in the country for ≥15 years) aged ≥18 years (approximately one-fifth of all Qatari citizens), to follow up these same individuals over the long term to record any subsequent disease, and hence to study the causes and progression of disease, and disease burden, in the Qatari population.

Methods

Between the 11th-December-2012 and 20th-February-2014, 1209 participants were recruited into the pilot study of the Qatar Biobank. At recruitment, extensive phenotype information was collected from each participant, including information/measurements of socio-demographic factors, prevalent health conditions, diet, lifestyle, anthropometry, body composition, bone health, cognitive function, grip strength, retinal imaging, total body dual energy X-ray absorptiometry, and measurements of cardiovascular and respiratory function. Blood, urine, and saliva were collected and stored for future research use. A panel of 66 clinical biomarkers was routinely measured on fresh blood samples in all participants. Rates of recruitment are to be progressively increased in the coming period and the recruitment base widened to achieve a cohort of consented individuals broadly representative of the eligible Qatari population. In addition, it is planned to add additional measures in sub-samples of the cohort, including Magnetic Resonance Imaging (MRI) of the brain, heart and abdomen.

Results

The mean time for collection of the extensive phenotypic information and biological samples from each participant at the baseline recruitment visit was 179 min. The 1209 pilot study participants (506 men and 703 women) were aged between 28–80 years (median 39 years); 899 (74.4 %) were Qatari nationals and 310 (25.6 %) were long-term residents. Approximately two-thirds of pilot participants were educated to graduate level or above.

Conclusions

The pilot has proven that recruitment of volunteers into the Qatar Biobank project with intensive baseline measurements of behavioural, physical, and clinical characteristics is well accepted and logistically feasible. Qatar Biobank will provide a powerful resource to investigate the major determinants of ill-health and well-being in Qatar, providing valuable insights into the current and future public health burden that faces the country.
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