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Breast Cancer Research and Treatment

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19.04.2019 | Review

The relation between stressful life events and breast cancer: a systematic review and meta-analysis of cohort studies

verfasst von: Narjes Bahri, Tahereh Fathi Najafi, Fatemeh Homaei Shandiz, Hamid Reza Tohidinik, Abdoljavad Khajavi

Erschienen in: Breast Cancer Research and Treatment | Ausgabe 1/2019

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Abstract

Purpose

Breast cancer is the most common cancer among women with high rate of mortality. This systematic review and meta-analysis was conducted to investigate the relation between stressful life events and breast cancer.

Methods

We searched PubMed, Scopus, ScienceDirect, and Google scholar databases from their inception until June 2018. The keywords and phrases we used in the search were (life events AND stress AND breast cancer OR neoplasm) to identify potentially relevant cohort studies that reported relative risk estimates and confidence intervals of this association. Pooled Risk ratio and 95% confidence intervals (CIs) were calculated using random effects model.

Results

Out of 168 potentially relevant publications, 11 documents met the inclusion criteria. The results showed that history of stressful life events slightly increases the risk of breast cancer [pooled Risk Ratio: 1.11 (95% CI 1.03 to 1.19)].

Conclusions

History of stressful life events could be associated with a moderate increase in the risk of breast cancer. We advise that receiving psychological and counseling services after occurrence of stressful life events of women should be taken seriously.

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Titel: The relation between stressful life events and breast cancer: a systematic review and meta-analysis of cohort studies
verfasst von: Narjes Bahri
Tahereh Fathi Najafi
Fatemeh Homaei Shandiz
Hamid Reza Tohidinik
Abdoljavad Khajavi
Publikationsdatum: 19.04.2019
Verlag: Springer US
Erschienen in: Breast Cancer Research and Treatment / Ausgabe 1/2019
Print ISSN: 0167-6806
Elektronische ISSN: 1573-7217
DOI: https://doi.org/10.1007/s10549-019-05231-x

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The relation between stressful life events and breast cancer: a systematic review and meta-analysis of cohort studies

Abstract

Purpose

Methods

Results

Conclusions

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Stereotaktische Radiatio schlägt konventionelle Bestrahlung

Adjuvante Brustkrebstherapie: Doppelt hält besser

HNO-Op. auch mit über 90?

Manche Gestagene können das Risiko für Meningeome erhöhen

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusions

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