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Erschienen in: The Journal of Obstetrics and Gynecology of India 2/2014

01.04.2014 | Original Article

The Risk Factors for Failure of Labor Induction: A Cohort Study

verfasst von: Emilio Giugliano, Elisa Cagnazzo, Viviana Milillo, Massimo Moscarini, Fortunato Vesce, Donatella Caserta, Roberto Marci

Erschienen in: The Journal of Obstetrics and Gynecology of India | Ausgabe 2/2014

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Abstract

Purpose

To assess how some factors may influence the failure of labor induction.

Methods

We conducted a prospective observational study from January 2009 to December 2011 with 248 patients who were admitted to the Obstetrics Unit of Ferrara University for labor induction. We selected only patients with unfavorable characteristics such as nulliparity, maternal and gestational age, and Bishop score and specific obstetric conditions such as mild preeclampsia, isolated oligohydramnios, premature rupture membrane, gestational diabetes, and hypertension for the success of labor induction.

Results

The induction was carried out by rapid-release gel dinoprostone. 200 patients (80.6 %) delivered vaginally (Group A), while 48 (19.4 %) underwent a cesarean section (Group B). Maternal age was one independent significant variable (p = 0.01, OR 1.08) determining the risk of cesarean delivery. Patients affected by mild preeclampsia had a three times higher risk for cesarean section. Despite the several unfavorable characteristics of the patients, the cesarean section rate was comparable to that of the normal population.

Conclusions

Several factors and clinical conditions historically considered as negative predictors of induction result should be reassessed. The success of labor induction is determined by many maternal and fetal variables, which must all be taken into account to avoid unnecessary cesarean sections.
Literatur
1.
Zurück zum Zitat Pandis GK, Papageorghiou AT, Ramanathan VG, et al. Preinduction sonographic measurement of cervical length in the prediction of successful induction of labor. Ultrasound Obstet Gynecol. 2001;18:623–8.PubMedCrossRef Pandis GK, Papageorghiou AT, Ramanathan VG, et al. Preinduction sonographic measurement of cervical length in the prediction of successful induction of labor. Ultrasound Obstet Gynecol. 2001;18:623–8.PubMedCrossRef
2.
Zurück zum Zitat Gülmezoglu AM, Crowther CA, Middleton P, et al. Induction of labour for improving birth outcomes for women at or beyond term. Cochrane Database Syst Rev. 2012;13(6):CD004945. Gülmezoglu AM, Crowther CA, Middleton P, et al. Induction of labour for improving birth outcomes for women at or beyond term. Cochrane Database Syst Rev. 2012;13(6):CD004945.
3.
Zurück zum Zitat Park KH, Hong JS, Ko JK, et al. Comparative study of induction of labor in nulliparous women with premature rupture of membranes at term compared to those with intact membranes: duration of labor and mode of delivery. J Obstet Gynaecol Res. 2006;32:482–8.PubMedCrossRef Park KH, Hong JS, Ko JK, et al. Comparative study of induction of labor in nulliparous women with premature rupture of membranes at term compared to those with intact membranes: duration of labor and mode of delivery. J Obstet Gynaecol Res. 2006;32:482–8.PubMedCrossRef
4.
Zurück zum Zitat Tucker Edmonds B, Fager C, Srinivas S, et al. Predictors of cesarean delivery for periviable neonates. Obstet Gynecol. 2011;118:49–56.PubMedCrossRef Tucker Edmonds B, Fager C, Srinivas S, et al. Predictors of cesarean delivery for periviable neonates. Obstet Gynecol. 2011;118:49–56.PubMedCrossRef
5.
Zurück zum Zitat Xenakis EM, Piper JM, Field N, et al. Preeclampsia: is induction of labor more successful? Obstet Gynecol. 1997;89:600–3.PubMedCrossRef Xenakis EM, Piper JM, Field N, et al. Preeclampsia: is induction of labor more successful? Obstet Gynecol. 1997;89:600–3.PubMedCrossRef
6.
Zurück zum Zitat Mozurkewich EL, Chilimigras JL, Berman DR, et al. Methods of induction of labour: a systematic review. BMC Pregnancy Childbirth. 2011;27(11):84.CrossRef Mozurkewich EL, Chilimigras JL, Berman DR, et al. Methods of induction of labour: a systematic review. BMC Pregnancy Childbirth. 2011;27(11):84.CrossRef
7.
Zurück zum Zitat Cheng YW, Sparks TN, Laros RK Jr, et al. Impending macrosomia: will induction of labour modify the risk of caesarean delivery? BJOG. 2012;119:402–9.PubMedCentralPubMedCrossRef Cheng YW, Sparks TN, Laros RK Jr, et al. Impending macrosomia: will induction of labour modify the risk of caesarean delivery? BJOG. 2012;119:402–9.PubMedCentralPubMedCrossRef
8.
Zurück zum Zitat Jackson GL, Rawiki P, Sendelbach D, et al. Hospital course and short-term outcomes of term and late preterm neonates following exposure to prolonged rupture of membranes and/or chorioamnionitis. Pediatr Infect Dis J. 2012;31:89–90.PubMedCrossRef Jackson GL, Rawiki P, Sendelbach D, et al. Hospital course and short-term outcomes of term and late preterm neonates following exposure to prolonged rupture of membranes and/or chorioamnionitis. Pediatr Infect Dis J. 2012;31:89–90.PubMedCrossRef
9.
Zurück zum Zitat Sibai BM. Management of late preterm and early-term pregnancies complicated by mild gestational hypertension/pre-eclampsia. Semin Perinatol. 2011;35:292–6.PubMedCrossRef Sibai BM. Management of late preterm and early-term pregnancies complicated by mild gestational hypertension/pre-eclampsia. Semin Perinatol. 2011;35:292–6.PubMedCrossRef
10.
Zurück zum Zitat Chauhan SP, Sanderson M, Hendrix NW, et al. Perinatal outcome and amniotic fluid index in the antepartum and intrapartum periods: a meta-analysis. Am J Obstet Gynecol. 1999;181:1473–8.PubMedCrossRef Chauhan SP, Sanderson M, Hendrix NW, et al. Perinatal outcome and amniotic fluid index in the antepartum and intrapartum periods: a meta-analysis. Am J Obstet Gynecol. 1999;181:1473–8.PubMedCrossRef
11.
Zurück zum Zitat Ek S, Andersson A, Johansson A, et al. Oligohydramnios in uncomplicated pregnancies beyond 40 completed weeks. A prospective, randomised, pilot study on maternal and neonatal outcomes. Fetal Diagn Ther. 2005;20:182–5.PubMedCrossRef Ek S, Andersson A, Johansson A, et al. Oligohydramnios in uncomplicated pregnancies beyond 40 completed weeks. A prospective, randomised, pilot study on maternal and neonatal outcomes. Fetal Diagn Ther. 2005;20:182–5.PubMedCrossRef
12.
Zurück zum Zitat Voxman EG, Tran S, Wing DA, et al. Low amniotic fluid index as a predictor of adverse perinatal outcome. J Perinatol. 2002;22:282–5.PubMedCrossRef Voxman EG, Tran S, Wing DA, et al. Low amniotic fluid index as a predictor of adverse perinatal outcome. J Perinatol. 2002;22:282–5.PubMedCrossRef
13.
Zurück zum Zitat Crane JM. Factors predicting labor induction success: a critical analysis. Clin Obstet Gynecol. 2006;49:573–84.PubMedCrossRef Crane JM. Factors predicting labor induction success: a critical analysis. Clin Obstet Gynecol. 2006;49:573–84.PubMedCrossRef
14.
Zurück zum Zitat Sentilhes L, Bouet PE, Mezzadri M, et al. Assessment of the benefit-harm balance depending on gestationnal age to induce delivery for post-term pregnancies. J Gynecol Obstet Biol Reprod (Paris). 2011;40:747–66.CrossRef Sentilhes L, Bouet PE, Mezzadri M, et al. Assessment of the benefit-harm balance depending on gestationnal age to induce delivery for post-term pregnancies. J Gynecol Obstet Biol Reprod (Paris). 2011;40:747–66.CrossRef
15.
Zurück zum Zitat Kelly AJ, Malik S, Smith L, et al. Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term. Cochrane Database Syst Rev. 2009;7:CD003101. Kelly AJ, Malik S, Smith L, et al. Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term. Cochrane Database Syst Rev. 2009;7:CD003101.
16.
Zurück zum Zitat Sheiner E, Levy A, Katz M, et al. Gender does matter in perinatal medicine. Fetal Diagn Ther. 2004;19:366–9.PubMedCrossRef Sheiner E, Levy A, Katz M, et al. Gender does matter in perinatal medicine. Fetal Diagn Ther. 2004;19:366–9.PubMedCrossRef
17.
Zurück zum Zitat Reslan OM, Khalil RA. Molecular and vascular targets in the pathogenesis and management of the hypertension associated with preeclampsia. Cardiovasc Hematol Agents Med Chem. 2010;8:204–26.PubMedCentralPubMedCrossRef Reslan OM, Khalil RA. Molecular and vascular targets in the pathogenesis and management of the hypertension associated with preeclampsia. Cardiovasc Hematol Agents Med Chem. 2010;8:204–26.PubMedCentralPubMedCrossRef
Metadaten
Titel
The Risk Factors for Failure of Labor Induction: A Cohort Study
verfasst von
Emilio Giugliano
Elisa Cagnazzo
Viviana Milillo
Massimo Moscarini
Fortunato Vesce
Donatella Caserta
Roberto Marci
Publikationsdatum
01.04.2014
Verlag
Springer India
Erschienen in
The Journal of Obstetrics and Gynecology of India / Ausgabe 2/2014
Print ISSN: 0971-9202
Elektronische ISSN: 0975-6434
DOI
https://doi.org/10.1007/s13224-013-0486-z

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