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Current Treatment Options in Gastroenterology
Erschienen in: Current Treatment Options in Gastroenterology 4/2018

05.11.2018 | Motility (H Parkman and R Schey, Section Editors)

The Role of Botox in Colorectal Disorders

verfasst von: Dan Carter, MD, Ram Dickman, MD

Erschienen in: Current Treatment Options in Gastroenterology | Ausgabe 4/2018

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Abstract

Purpose of review

To overview the current medical literature on the efficacy of botulism toxin treatment (BTX-A) for lower gastrointestinal disorders (GIT).

Recent findings

BTX-A was found to have a short-term efficacy for the treatment of dyssynergic defecation. Surgical treatment was found to be more effective than BTX-A for the healing of chronic anal fissures, and BTX-A can be considered when surgery is undesirable. Data regarding the effects of BTX-A injection for the treatment of chronic anal pain is limited. Beneficial effects were observed only in a minority of patients. BTX-A treatment was found to be effective for the treatment of obstructive symptoms after surgery for Hirsprung’s disease as well as for the treatment of internal anal sphincter achalasia.

Summary

BTX-A treatment has a short-term efficacy and is safe. Further research is still needed in order to establish the exact place of BTX-A treatment of lower GIT disorders.
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Metadaten
Titel
The Role of Botox in Colorectal Disorders
verfasst von
Dan Carter, MD
Ram Dickman, MD
Publikationsdatum
05.11.2018
Verlag
Springer US
Erschienen in
Current Treatment Options in Gastroenterology / Ausgabe 4/2018
Print ISSN: 1092-8472
Elektronische ISSN: 1534-309X
DOI
https://doi.org/10.1007/s11938-018-0205-z

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