Skip to main content
main-content

01.12.2017 | Research | Ausgabe 1/2017 Open Access

Scoliosis and Spinal Disorders 1/2017

The role of the paravertebral muscles in adolescent idiopathic scoliosis evaluated by temporary paralysis

Zeitschrift:
Scoliosis and Spinal Disorders > Ausgabe 1/2017
Autoren:
Christian Wong, Kasper Gosvig, Stig Sonne-Holm

Abstract

Background

Muscle imbalance has been suggested as implicated in the pathology of adolescent idiopathic scoliosis (AIS). The specific “pathomechanic” role of the paravertebral muscles as being scoliogenic (inducing scoliosis) or counteracting scoliosis in the initial development and maintenance of this spinal deformity has yet to be clarified in humans. In the present study, we investigated the radiographic changes of temporal paralysis using botulinum toxin A as localized injection therapy (ITB) in the psoas major muscle in AIS patients.

Methods

Nine patients with AIS were injected one time with ITB using ultrasonic and EMG guidance in the selected spine muscles. Radiographic and clinical examinations were performed before and 6 weeks after the injection. Primary outcome parameters of radiological changes were analyzed using Wilcoxon signed-rank test and binomial test, and secondary outcome parameters of short- and long-term clinical effects were obtained.

Results

Significant radiological corrective changes were seen in the frontal plane in the thoracic and lumbar spine as well as significant derotational corrective change in the lumbar spine according to Cobb’s angle measurements and to Nash and Moe’s classification, respectively. No serious adverse events were detected at follow-up.

Conclusions

In conclusion, this study demonstrated that the psoas major muscle do play a role into the pathology in adolescent idiopathic scoliosis by maintaining the curvature of the lumbar spine and thoracic spine.

Trial registration

EudraCT number 2008-004584-19
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2017

Scoliosis and Spinal Disorders 1/2017 Zur Ausgabe

Neu im Fachgebiet Orthopädie und Unfallchirurgie

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Orthopädie und Unfallchirurgie und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise