nach oben

Brain Structure and Function

Erschienen in:

23.01.2016 | Original Article

The system neurophysiological basis of backward inhibition

verfasst von: Rui Zhang, Ann-Kathrin Stock, Rico Fischer, Christian Beste

Erschienen in: Brain Structure and Function | Ausgabe 9/2016

Einloggen, um Zugang zu erhalten

Abstract

Task switching is regularly required in our everyday life. To succeed in switching, it is important to inhibit the most recently performed task and instead activate the currently relevant task. The process that inhibits a recently performed task when a new task is to be performed is referred to as ‘backward inhibition’ (BI). While the BI effect has been subject to intense research in cognitive psychology, little is known about the neuronal mechanisms that are related to the BI effect and those that relate to differences in the magnitude of the BI effect. In the current study, we examined the system neurophysiological basis of BI processes using event-related potentials (ERPs) and sLORETA by also taking inter-individual differences in the magnitude of the BI into account. The results suggest that BI processes and inter-individual differences in them strongly depend upon attentional selection mechanisms (reflected by N1-ERP modulations in the current task/trial) mediated via networks consisting of extrastriate occipital areas, the temporo-parietal junction and the inferior frontal gyrus. Other processes and mechanisms related to conflict monitoring, response selection, or the updating, organization and implementation of a new task-set (i.e. N2 and P3 processes) were not shown to be modulated by BI processes and differences in their magnitude, as evoked with a common BI paradigm.

Nur mit Berechtigung zugänglich

Allport A, Wylie G (1999) Task-switching: positive and negative priming of task-set. In: Humphreys GW, Duncan J, Treisman AM (eds) Attention, space and action: studies in cognitive neuroscience. Oxford University Press, Oxford, pp 273–296

Allport A, Styles EA, Hsieh S (1994) Shifting intentional set: exploring the dynamic control of task. In: Umiltà C, Moscovitch M (eds) Attention and performance XV: conscious and nonconscious information processing. MIT Press, Cambridge, pp 421–452

Aron AR, Robbins TW, Poldrack RA (2004) Inhibition and the right inferior frontal cortex. Trends Cogn Sci 8:170–177CrossRefPubMed

Banich MT (1998) The missing link: the role of interhemispheric interaction in attentional processing. Brain Cognit 36(2):128–157. doi:10.1006/brcg.1997.0950 CrossRef

Barceló F, Muñoz-Céspedes JM, Pozo MA, Rubia FJ (2000) Attentional set shifting modulates the target P3b response in the Wisconsin card sorting test. Neuropsychologia 38(10):1342–1355CrossRefPubMed

Beste C, Saft C, Andrich J, Gold R, Falkenstein M (2008) Stimulus-response compatibility in Huntington’s disease: a cognitive-neurophysiological analysis. J Neurophysiol 99(3):1213–1223. doi:10.1152/jn.01152.2007 CrossRefPubMed

Beste C, Baune BT, Falkenstein M, Konrad C (2010a) Variations in the TNF-α gene (TNF-α-308G→A) affect attention and action selection mechanisms in a dissociated fashion. J Neurophysiol 104(5):2523–2531. doi:10.1152/jn.00561.2010 CrossRefPubMed

Beste C, Willemssen R, Saft C, Falkenstein M (2010b) Response inhibition subprocesses and dopaminergic pathways: basal ganglia disease effects. Neuropsychologia 48(2):366–373. doi:10.1016/j.neuropsychologia.2009.09.023 CrossRefPubMed

Beste C, Ness V, Falkenstein M, Saft C (2011) On the role of fronto-striatal neural synchronization processes for response inhibition—evidence from ERP phase-synchronization analyses in pre-manifest Huntington’s disease gene mutation carriers. Neuropsychologia 49(12):3484–3493. doi:10.1016/j.neuropsychologia.2011.08.024 CrossRefPubMed

Bokura H, Yamaguchi S, Kobayashi S (2001) Electrophysiological correlates for response inhibition in a Go/NoGo task. Clin Neurophysiol Off J Int Fed Clin Neurophysiol 112(12):2224–2232CrossRef

Cabeza R, Ciaramelli E, Moscovitch M (2012) Cognitive contributions of the ventral parietal cortex: an integrative theoretical account. Trends Cognit Sci 16(6):338–352. doi:10.1016/j.tics.2012.04.008 CrossRef

Costa RE, Friedrich FJ (2012) Inhibition, interference, and conflict in task switching. Psychon Bull Rev 19(6):1193–1201. doi:10.3758/s13423-012-0311-1 CrossRefPubMed

Deng Y, Wang Y, Ding X, Tang Y-Y (2015) Conflict monitoring and adjustment in the task-switching paradigm under different memory load conditions: an ERP/sLORETA analysis. Neuroreport. doi:10.1097/WNR.0000000000000310 PubMed

Dippel G, Beste C (2015) A causal role of the right inferior frontal cortex in the strategies of multi-component behaviour. Nature Commun. doi:10.1038/ncomms7587

Donkers FCL, van Boxtel GJM (2004) The N2 in go/no-go tasks reflects conflict monitoring not response inhibition. Brain Cognit 56(2):165–176. doi:10.1016/j.bandc.2004.04.005 CrossRef

Dreher JC, Berman KF (2002) Fractionating the neural substrate of cognitive control processes. Proc Natl Acad Sci USA 99:14595–14600CrossRefPubMedPubMedCentral

Druey MD, Hübner R (2007) The role of temporal cue-target overlap in backward inhibition under task switching. Psychon Bull Rev 14(4):749–754CrossRefPubMed

Falkenstein M, Hohnsbein J, Hoormann J (1994a) Effects of choice complexity on different subcomponents of the late positive complex of the event-related potential. Electroencephalogr Clin Neurophysiol 92(2):148–160CrossRefPubMed

Falkenstein M, Hohnsbein J, Hoormann J (1994b) Time pressure effect on late components of the event-related potential (ERP). J Psychophysiol 8:22–30

Fuchs M, Kastner J, Wagner M, Hawes S, Ebersole JS (2002) A standardized boundary element method volume conductor model. Clin Neurophysiol Off J Int Fed Clin Neurophysiol 113(5):702–712CrossRef

Gade M, Koch I (2008) Dissociating cue-related and task-related processes in task inhibition: evidence from using a 2:1 cue-to-task mapping. Can J Exp Psychol Revue Canadienne de Psychologie Expérimentale 62(1):51–55. doi:10.1037/1196-1961.62.1.51 CrossRefPubMed

Gajewski PD, Wild-Wall N, Schapkin SA, Erdmann U, Freude G, Falkenstein M (2010) Effects of aging and job demands on cognitive flexibility assessed by task switching. Biol Psychol 85(2):187–199. doi:10.1016/j.biopsycho.2010.06.009 CrossRefPubMed

Gajewski PD, Hengstler JG, Golka K, Falkenstein M, Beste C (2011) The Met-allele of the BDNF Val66Met polymorphism enhances task switching in elderly. Neurobiol Aging 32(12):2327.e7–19. doi:10.1016/j.neurobiolaging.2011.06.010

Gehring WJ, Bryck RL, Jonides J, Albin RL, Badre D (2003) The mind’s eye, looking inward? In search of executive control in internal attention shifting. Psychophysiology 40(4):572–585CrossRefPubMed

Geng JJ, Vossel S (2013) Re-evaluating the role of TPJ in attentional control: contextual updating? Neurosci Biobehav Rev 37(10, Part 2):2608–2620. doi:10.1016/j.neubiorev.2013.08.010

Getzmann S, Gajewski PD, Hengstler JG, Falkenstein M, Beste C (2013) BDNF Val66Met polymorphism and goal-directed behavior in healthy elderly—evidence from auditory distraction. NeuroImage 64:290–298. doi:10.1016/j.neuroimage.2012.08.079 CrossRefPubMed

Goffaux P, Phillips NA, Sinai M, Pushkar D (2006) Behavioural and electrophysiological measures of task switching during single and mixed-task conditions. Biol Psychol 72(3):278–290. doi:10.1016/j.biopsycho.2005.11.009 CrossRefPubMed

Herrmann CS, Knight RT (2001) Mechanisms of human attention: event-related potentials and oscillations. Neurosci Biobehav Rev 25(6):465–476CrossRefPubMed

Hillyard SA, Anllo-Vento L (1998) Event-related brain potentials in the study of visual selective attention. Proc Natl Acad Sci USA 95(3):781–787CrossRefPubMedPubMedCentral

Hilti CC, Jann K, Heinemann D, Federspiel A, Dierks T, Seifritz E, Cattapan-Ludewig K (2013) Evidence for a cognitive control network for goal-directed attention in simple sustained attention. Brain Cognit 81(2):193–202. doi:10.1016/j.bandc.2012.10.013 CrossRef

Huster RJ, Enriquez-Geppert S, Lavallee CF, Falkenstein M, Herrmann CS (2013) Electroencephalography of response inhibition tasks: functional networks and cognitive contributions. Int J Psychophysiol 87(3):217–233. doi:10.1016/j.ijpsycho.2012.08.001 CrossRefPubMed

Johnson JA, Zatorre RJ (2005) Attention to simultaneous unrelated auditory and visual events: behavioral and neural correlates. Cereb Cortex (New York, N.Y.: 1991) 15(10):1609–1620. doi:10.1093/cercor/bhi039

Karayanidis F, Coltheart M, Michie PT, Murphy K (2003) Electrophysiological correlates of anticipatory and poststimulus components of task switching. Psychophysiology 40(3):329–348CrossRefPubMed

Katzir M, Ori B, Hsieh S, Meiran N (2015) Competitor rule priming: evidence for priming of task rules in task switching. Psychol Res 79(3):446–462. doi:10.1007/s00426-014-0583-3 CrossRefPubMed

Kieffaber PD, Hetrick WP (2005) Event-related potential correlates of task switching and switch costs. Psychophysiology 42(1):56–71. doi:10.1111/j.1469-8986.2005.00262.x CrossRefPubMed

Kiesel A, Steinhauser M, Wendt M, Falkenstein M, Jost K, Philipp AM, Koch I (2010) Control and interference in task switching—a review. Psychol Bull 136(5):849–874. doi:10.1037/a0019842 CrossRefPubMed

Koch I, Gade M, Philipp AM (2004) Inhibition of response mode in task switching. Exp Psychol 51:52–58. doi:10.1027/1617-3169.51.1.52 CrossRefPubMed

Koch I, Gade M, Schuch S, Philipp AM (2010) The role of inhibition in task switching: a review. Psychon Bull Rev 17(1):1–14. doi:10.3758/PBR.17.1.1 CrossRefPubMed

Larson MJ, Clayson PE, Clawson A (2014) Making sense of all the conflict: a theoretical review and critique of conflict-related ERPs. Int J Psychophysiol Off J Int Org Psychophysiol 93(3):283–297. doi:10.1016/j.ijpsycho.2014.06.007

Logan GD, Bundesen C (2003) Clever homunculus: is there an endogenous act of control in the explicit task-cuing procedure? J Exp Psychol Hum Percept Perform 29:575–599CrossRefPubMed

Lopez-Larson MP, King JB, Terry J, McGlade EC, Yurgelun-Todd D (2012) Reduced insular volume in attention deficit hyperactivity disorder. Psychiatry Res 204(1):32–39. doi:10.1016/j.pscychresns.2012.09.009 CrossRefPubMedPubMedCentral

Lorist MM, Klein M, Nieuwenhuis S, De Jong R, Mulder G, Meijman TF (2000) Mental fatigue and task control: planning and preparation. Psychophysiology 37(5):614–625CrossRefPubMed

Luck SJ, Heinze HJ, Mangun GR, Hillyard SA (1990) Visual event-related potentials index focused attention within bilateral stimulus arrays. II. Functional dissociation of P1 and N1 components. Electroencephalogr Clin Neurophysiol 75(6):528–542CrossRefPubMed

Luck SJ, Chelazzi L, Hillyard SA, Desimone R (1997) Neural mechanisms of spatial selective attention in areas V1, V2, and V4 of macaque visual cortex. J Neurophysiol 77(1):24–42PubMed

Marco-Pallarés J, Grau C, Ruffini G (2005) Combined ICA-LORETA analysis of mismatch negativity. NeuroImage 25(2):471–477. doi:10.1016/j.neuroimage.2004.11.028 CrossRefPubMed

Masson MEJ (2011) A tutorial on a practical Bayesian alternative to null-hypothesis significance testing. Behav Res Methods 43(3):679–690. doi:10.3758/s13428-010-0049-5 CrossRefPubMed

Mattler U, Wüstenberg T, Heinze H-J (2006) Common modules for processing invalidly cued events in the human cortex. Brain Res 1109(1):128–141. doi:10.1016/j.brainres.2006.06.051 CrossRefPubMed

Mayr U, Keele SW (2000) Changing internal constraints on action: the role of backward inhibition. J Exp Psychol Gen 129(1):4–26CrossRefPubMed

Mayr U, Diedrichsen J, Ivry R, Keele SW (2006) Dissociating task-set selection from task-set inhibition in the prefrontal cortex. J Cogn Neurosci 18:14–21CrossRefPubMed

Micheli C, Kaping D, Westendorff S, Valiante TA, Womelsdorf T (2015) Inferior-frontal cortex phase synchronizes with the temporal-parietal junction prior to successful change detection. NeuroImage. doi:10.1016/j.neuroimage.2015.06.043 PubMed

Mincic AM (2010) Neural substrate of the cognitive and emotional interference processing in healthy adolescents. Acta Neurobiologiae Experimentalis 70(4):406–422PubMed

Monsell S (2003) Task switching. Trends Cognit Sci 7(3):134–140. doi:10.1016/S1364-6613(03)00028-7 CrossRef

Mückschel M, Stock A-K, Beste C (2014) Psychophysiological mechanisms of interindividual differences in goal activation modes during action cascading. Cereb Cortex (New York, N.Y.: 1991) 24(8):2120–2129. doi:10.1093/cercor/bht066

Munneke J, Heslenfeld DJ, Usrey WM, Theeuwes J, Mangun GR (2011) Preparatory effects of distractor suppression: evidence from visual cortex. PloS One 6(12):e27700. doi:10.1371/journal.pone.0027700 CrossRefPubMedPubMedCentral

Nicholson R, Karayanidis F, Poboka D, Heathcote A, Michie PT (2005) Electrophysiological correlates of anticipatory task-switching processes. Psychophysiology 42(5):540–554. doi:10.1111/j.1469-8986.2005.00350.x PubMed

Nicholson R, Karayanidis F, Davies A, Michie PT (2006) Components of task-set reconfiguration: differential effects of “switch-to” and “switch-away” cues. Brain Res 1121(1):160–176. doi:10.1016/j.brainres.2006.08.101 CrossRefPubMed

Nunez PL, Pilgreen KL (1991) The spline-Laplacian in clinical neurophysiology: a method to improve EEG spatial resolution. J Clin Neurophysiol Off Publ Am Electroencephalogr Soc 8(4):397–413

Oldfield RC (1971) The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9(1):97–113CrossRefPubMed

Pammer K, Hansen P, Holliday I, Cornelissen P (2006) Attentional shifting and the role of the dorsal pathway in visual word recognition. Neuropsychologia 44(14):2926–2936. doi:10.1016/j.neuropsychologia.2006.06.028 CrossRefPubMed

Pascual-Marqui RD (2002) Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details. Methods Find Exp Clin Pharmacol 24(Suppl D):5–12

Pessoa L, Rossi A, Japee S, Desimone R, Ungerleider LG (2009) Attentional control during the transient updating of cue information. Brain Res 1247:149–158. doi:10.1016/j.brainres.2008.10.010 CrossRefPubMed

Philipp AM, Koch I (2005) Switching of response modalities. Q J Exp Psychol A 58:1325–1338CrossRefPubMed

Philipp AM, Weidner R, Koch I, Fink GR (2013) Differential roles of inferior frontal and inferior parietal cortex in task switching: evidence from stimulus-categorization switching and response-modality switching. Human Brain Mapp 34(8):1910–1920. doi:10.1002/hbm.22036 CrossRef

Raftery AE (1995) Bayesian model selection in social research. In: Mardsen P (ed) Sociological methodology. Blackwell, Cambridge, pp 11–196

Regev S, Meiran N (2015) Cue-type manipulation dissociates two types of task set inhibition: backward inhibition and competitor rule suppression. Psychol Res. doi:10.1007/s00426-015-0663-z PubMed

Reynolds JH, Desimone R (1999) The role of neural mechanisms of attention in solving the binding problem. Neuron 24(1):19–29, 111–125

Rossi AF, Pessoa L, Desimone R, Ungerleider LG (2009) The prefrontal cortex and the executive control of attention. Exp Brain Res 192(3):489–497. doi:10.1007/s00221-008-1642-z CrossRefPubMed

Rushworth MFS, Passingham RE, Nobre AC (2002) Components of switching intentional set. J Cognit Neurosci 14(8):1139–1150. doi:10.1162/089892902760807159 CrossRef

Scheil J, Kleinsorge T (2014) N − 2 repetition costs depend on preparation in trials n − 1 and n − 2. J Exp Psychol Learn Mem Cognit 40(3):865–872. doi:10.1037/a0035281 CrossRef

Schuch S, Koch I (2003) The role of response selection for inhibition of task sets in task shifting. J Exp Psychol Human Percept Perform 29(1):92–105. doi:10.1037/0096-1523.29.1.92 CrossRef

Sekihara K, Sahani M, Nagarajan SS (2005) Localization bias and spatial resolution of adaptive and non-adaptive spatial filters for MEG source reconstruction. NeuroImage 25(4):1056–1067. doi:10.1016/j.neuroimage.2004.11.051 CrossRefPubMedPubMedCentral

Sinai M, Goffaux P, Phillips NA (2007) Cue-versus response-locked processes in backward inhibition: evidence from ERPs. Psychophysiology 44(4):596–609. doi:10.1111/j.1469-8986.2007.00527.x CrossRefPubMed

Stock A-K, Gohil K, Beste C (2015) Age-related differences in task goal processing strategies during action cascading. Brain Struct Funct. doi:10.1007/s00429-015-1071-2

Thiel CM, Fink GR (2008) Effects of the cholinergic agonist nicotine on reorienting of visual spatial attention and top-down attentional control. Neuroscience 152(2):381–390. doi:10.1016/j.neuroscience.2007.10.061 CrossRefPubMed

Uddin LQ (2015) Salience processing and insular cortical function and dysfunction. Nature Rev Neurosci 16(1):55–61. doi:10.1038/nrn3857 CrossRef

Van Veen V, Carter CS (2002) The anterior cingulate as a conflict monitor: fMRI and ERP studies. Physiol Behav 77(4–5):477–482CrossRefPubMed

Verleger R, Jaśkowski P, Wascher E (2005) Evidence for an integrative role of P3b in linking reaction to perception. J Psychophysiol 19(3):165–181CrossRef

Vidyasagar TR (1999) A neuronal model of attentional spotlight: parietal guiding the temporal. Brain Res Brain Res Rev 30(1):66–76CrossRefPubMed

Vossel S, Thiel CM, Fink GR (2006) Cue validity modulates the neural correlates of covert endogenous orienting of attention in parietal and frontal cortex. NeuroImage 32(3):1257–1264. doi:10.1016/j.neuroimage.2006.05.019 CrossRefPubMed

Wagenmakers E-J (2007) A practical solution to the pervasive problems of p values. Psychon Bull Rev 14(5):779–804CrossRefPubMed

Wascher E, Beste C (2010) Tuning perceptual competition. J Neurophysiol 103(2):1057–1065. doi:10.1152/jn.00376.2009 CrossRefPubMed

Whitmer AJ, Banich MT (2012) Brain activity related to the ability to inhibit previous task sets: an fMRI study. Cognit Affect Behav Neurosci 12(4):661–670. doi:10.3758/s13415-012-0118-6 CrossRef

Titel: The system neurophysiological basis of backward inhibition
verfasst von: Rui Zhang
Ann-Kathrin Stock
Rico Fischer
Christian Beste
Publikationsdatum: 23.01.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: Brain Structure and Function / Ausgabe 9/2016
Print ISSN: 1863-2653
Elektronische ISSN: 1863-2661
DOI: https://doi.org/10.1007/s00429-016-1186-0

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Neurologie

23.04.2024 | Demenz | Nachrichten

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

The system neurophysiological basis of backward inhibition

Abstract

Leitlinien kompakt für die Neurologie

Neu im Fachgebiet Neurologie

Demenzkranke durch Antipsychotika vielfach gefährdet

Parkinson-Therapie im Wandel – aktuelle Leitlinie im Fokus

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Hustenstiller lindert Agitation bei Alzheimer

Update Neurologie

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 9/2016

Attentional function and basal forebrain cholinergic neuron morphology during aging in the Ts65Dn mouse model of Down syndrome

mGluR4-containing corticostriatal terminals: synaptic interactions with direct and indirect pathway neurons in mice

Alcohol dependence-induced regulation of the proliferation and survival of adult brain progenitors is associated with altered BDNF-TrkB signaling

Projections from a single NUCB2/nesfatin-1 neuron in the paraventricular nucleus to different brain regions involved in feeding

A single-neuron tracing study of arkypallidal and prototypic neurons in healthy rats

Altered resonance properties of somatosensory responses in mice deficient for the schizophrenia risk gene Neuregulin 1

Leitlinien kompakt für die Neurologie

Neu im Fachgebiet Neurologie

Demenzkranke durch Antipsychotika vielfach gefährdet

Parkinson-Therapie im Wandel – aktuelle Leitlinie im Fokus

Auf diese Krankheiten bei Geflüchteten sollten Sie vorbereitet sein

Hustenstiller lindert Agitation bei Alzheimer

Update Neurologie