Anzeige
06.09.2024 | Head and Neck
The utility and reliability of a deep learning algorithm as a diagnosis support tool in head & neck non-melanoma skin malignancies
Erschienen in: European Archives of Oto-Rhino-Laryngology
Einloggen, um Zugang zu erhaltenAbstract
Objective
The incidence of non-melanoma skin cancers, encompassing basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), is on the rise globally and new methods to improve skin malignancy diagnosis are necessary. This study aims to assess the performance of a CE-certified medical device as a diagnosis support tool in a head & neck (H&N) outpatient clinic, specifically focusing on the classification of three key diagnostics: BCC, cSCC, and non-malignant lesions (such as Actinic Cheilitis, Actinic Keratosis, and Seborrheic Keratosis).
Methods
a prospective, longitudinal, non-randomized study was designed to evaluate the performance of a deep learning-based method as a diagnosis tool in a group of patients referred to the head & neck clinic for suspicious skin lesions.
Results
135 patients were included, 92 (68.1%) were male and 43 (31.9%) were female. The median age was 71 years +/- 9 (Min: 56/Max: 91). Of those, 108 were malignant pathologies (54 basal cell carcinoma and 54 squamous cell carcinoma) and 27 benign pathologies (14 seborrheic keratoses, 2 actinic keratoses, and 11 actinic cheilitis). Of special significance is the remarkable performance of the medical device in identifying malignant lesions (basal cell carcinoma and squamous cell carcinoma) within the top-5 most likely diagnoses in above 90% of cases, underscoring its potential utility for early diagnosis and treatment.
Conclusion
In this study, the effectiveness of deep learning methods, with a particular focus on vision transformers, as a diagnostic aid for H&N cutaneous non-melanoma skin cancers was demonstrated, highlighting its potential value for early detection and treatment of non-melanoma skin cancers. In this vein, further research is needed in the future to elucidate the role of this technology, because of its potential in the primary care clinic, dermatology, and head & neck surgery clinic as well as in patients with suspicious lesions, as a self-exploration tool.
