Skip to main content
Erschienen in:

09.01.2024 | Scientific Article

The value of a repeat MRI examination of the sacroiliac joints following an inconclusive initial examination

verfasst von: Tamar Goitein Inbar, Merav Lidar, Iris Eshed

Erschienen in: Skeletal Radiology | Ausgabe 6/2024

Einloggen, um Zugang zu erhalten

Abstract

Objective

Assess the diagnostic utility of repeat sacroiliac joint (SIJ) magnetic resonance imaging (MRI) examinations following an inconclusive initial examination performed for suspected sacroiliitis.

Method

Subjects with > 1 SIJ MRI examinations, an inconclusive first scan and at least 6 months interval between scans, were included. All scans were evaluated for the presence of structural/active SIJ lesions as well as any other pathology. Clinical data was extracted from the patients’ clinical files, and any missing data was obtained by a telephone interview. Diagnosis and active/structural scores were compared between first and follow-up examinations (t test).

Results

Seventy-one subjects were included in the study, 77.4% females, mean age 41.0 ± 15 years, mean time interval between exams 30.4 ± 25.24 months. Twelve subjects performed > 2 scans. In only two subjects (2.81%), both females, MRI diagnosis changed from inconclusive to definite sacroiliitis. None of the subjects with > 2 scans had evidence of sacroiliitis in any of the following MRI examinations. Significant differences were observed between the scores of active SIJ lesion of the first and follow-up MRI (1.51/1.62, p = 0.02) but not for scores of structural lesions (1.22/1.68, p = 0.2).

Conclusions

Repeat SIJ MRI when the first MRI is inconclusive for sacroiliitis is more valuable in ruling out than in securing diagnosis of sacroiliitis. We suggest that when MRI findings are inconclusive, decision-making should be based on clinical data.
Literatur
2.
Zurück zum Zitat Zochling J, Brandt J, Braun J. The current concept of spondyloarthritis with special emphasis on undifferentiated spondyloarthritis. Rheumatology (Oxford). 2005;44(12):1483–91.CrossRefPubMed Zochling J, Brandt J, Braun J. The current concept of spondyloarthritis with special emphasis on undifferentiated spondyloarthritis. Rheumatology (Oxford). 2005;44(12):1483–91.CrossRefPubMed
3.
Zurück zum Zitat Rudwaleit M, Jurik AG, Hermann KG, Landewe R, van der Heijde D, Baraliakos X, et al. Defining active sacroiliitis on magnetic resonance imaging (MRI) for classification of axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI group. Ann Rheum Dis. 2009;68(10):1520–7.CrossRefPubMed Rudwaleit M, Jurik AG, Hermann KG, Landewe R, van der Heijde D, Baraliakos X, et al. Defining active sacroiliitis on magnetic resonance imaging (MRI) for classification of axial spondyloarthritis: a consensual approach by the ASAS/OMERACT MRI group. Ann Rheum Dis. 2009;68(10):1520–7.CrossRefPubMed
4.
Zurück zum Zitat Eshed I, Miloh-Raz H, Dulitzki M, Lidar Z, Aharoni D, Liberman B, et al. Peripartum changes of the sacroiliac joints on MRI: increasing mechanical load correlating with signs of edema and inflammation kindling spondyloarthropathy in the genetically prone. Clin Rheumatol. 2015;34(8):1419–26.CrossRefPubMed Eshed I, Miloh-Raz H, Dulitzki M, Lidar Z, Aharoni D, Liberman B, et al. Peripartum changes of the sacroiliac joints on MRI: increasing mechanical load correlating with signs of edema and inflammation kindling spondyloarthropathy in the genetically prone. Clin Rheumatol. 2015;34(8):1419–26.CrossRefPubMed
5.
Zurück zum Zitat Renson T, Depicker A, De Craemer AS, Deroo L, Varkas G, de Hooge M, et al. High prevalence of spondyloarthritis-like MRI lesions in postpartum women: a prospective analysis in relation to maternal, child and birth characteristics. Ann Rheum Dis. 2020;79(7):929–34.CrossRefPubMed Renson T, Depicker A, De Craemer AS, Deroo L, Varkas G, de Hooge M, et al. High prevalence of spondyloarthritis-like MRI lesions in postpartum women: a prospective analysis in relation to maternal, child and birth characteristics. Ann Rheum Dis. 2020;79(7):929–34.CrossRefPubMed
6.
Zurück zum Zitat Poddubnyy D, Weineck H, Diekhoff T, Redeker I, Gobejishvili N, Llop M, et al. Clinical and imaging characteristics of osteitis condensans ilii as compared with axial spondyloarthritis. Rheumatology (Oxford). 2020;59(12):3798–806.CrossRefPubMed Poddubnyy D, Weineck H, Diekhoff T, Redeker I, Gobejishvili N, Llop M, et al. Clinical and imaging characteristics of osteitis condensans ilii as compared with axial spondyloarthritis. Rheumatology (Oxford). 2020;59(12):3798–806.CrossRefPubMed
7.
Zurück zum Zitat Weber U, Jurik AG, Zejden A, Larsen E, Jorgensen SH, Rufibach K, et al. MRI of the sacroiliac joints in athletes: recognition of non-specific bone marrow oedema by semi-axial added to standard semi-coronal scans. Rheumatology (Oxford). 2020;59(6):1381–90.CrossRefPubMed Weber U, Jurik AG, Zejden A, Larsen E, Jorgensen SH, Rufibach K, et al. MRI of the sacroiliac joints in athletes: recognition of non-specific bone marrow oedema by semi-axial added to standard semi-coronal scans. Rheumatology (Oxford). 2020;59(6):1381–90.CrossRefPubMed
8.
Zurück zum Zitat de Winter J, de Hooge M, van de Sande M, de Jong H, van Hoeven L, de Koning A, et al. Magnetic resonance imaging of the sacroiliac joints indicating sacroiliitis according to the Assessment of SpondyloArthritis international Society definition in healthy individuals, runners, and women with postpartum back pain. Arthritis & rheumatology. 2018;70(7):1042–8.CrossRef de Winter J, de Hooge M, van de Sande M, de Jong H, van Hoeven L, de Koning A, et al. Magnetic resonance imaging of the sacroiliac joints indicating sacroiliitis according to the Assessment of SpondyloArthritis international Society definition in healthy individuals, runners, and women with postpartum back pain. Arthritis & rheumatology. 2018;70(7):1042–8.CrossRef
9.
Zurück zum Zitat Lukas C, Cyteval C, Dougados M, Weber U. MRI for diagnosis of axial spondyloarthritis: major advance with critical limitations ‘Not everything that glisters is gold (standard).’ RMD Open. 2018;4(1): e000586.CrossRefPubMedPubMedCentral Lukas C, Cyteval C, Dougados M, Weber U. MRI for diagnosis of axial spondyloarthritis: major advance with critical limitations ‘Not everything that glisters is gold (standard).’ RMD Open. 2018;4(1): e000586.CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Weber U, Lambert RG, Pedersen SJ, Hodler J, Ostergaard M, Maksymowych WP. Assessment of structural lesions in sacroiliac joints enhances diagnostic utility of magnetic resonance imaging in early spondylarthritis. Arthritis Care Res. 2010;62(12):1763–71.CrossRef Weber U, Lambert RG, Pedersen SJ, Hodler J, Ostergaard M, Maksymowych WP. Assessment of structural lesions in sacroiliac joints enhances diagnostic utility of magnetic resonance imaging in early spondylarthritis. Arthritis Care Res. 2010;62(12):1763–71.CrossRef
11.
Zurück zum Zitat Song IH, Hermann K, Haibel H, Althoff CE, Listing J, Burmester G, et al. Effects of etanercept versus sulfasalazine in early axial spondyloarthritis on active inflammatory lesions as detected by whole-body MRI (ESTHER): a 48-week randomised controlled trial. Ann Rheum Dis. 2011;70(4):590–6.CrossRefPubMed Song IH, Hermann K, Haibel H, Althoff CE, Listing J, Burmester G, et al. Effects of etanercept versus sulfasalazine in early axial spondyloarthritis on active inflammatory lesions as detected by whole-body MRI (ESTHER): a 48-week randomised controlled trial. Ann Rheum Dis. 2011;70(4):590–6.CrossRefPubMed
12.
Zurück zum Zitat Bakker PAC, Ramiro S, Ez-Zaitouni Z, van Lunteren M, Berg IJ, Landewe R, et al. Is it useful to repeat magnetic resonance imaging of the sacroiliac joints after three months or one year in the diagnosis of patients with chronic back pain and suspected axial spondyloarthritis? Arthritis & rheumatology. 2019;71(3):382–91.CrossRef Bakker PAC, Ramiro S, Ez-Zaitouni Z, van Lunteren M, Berg IJ, Landewe R, et al. Is it useful to repeat magnetic resonance imaging of the sacroiliac joints after three months or one year in the diagnosis of patients with chronic back pain and suspected axial spondyloarthritis? Arthritis & rheumatology. 2019;71(3):382–91.CrossRef
13.
Zurück zum Zitat Sengupta R, Marzo-Ortega H, McGonagle D, Wadeley A, Bennett AN. Short-term repeat magnetic resonance imaging scans in suspected early axial spondyloarthritis are clinically relevant only in HLA-B27-positive male subjects. J Rheumatol. 2018;45(2):202–5.CrossRefPubMed Sengupta R, Marzo-Ortega H, McGonagle D, Wadeley A, Bennett AN. Short-term repeat magnetic resonance imaging scans in suspected early axial spondyloarthritis are clinically relevant only in HLA-B27-positive male subjects. J Rheumatol. 2018;45(2):202–5.CrossRefPubMed
14.
Zurück zum Zitat van Onna M, van Tubergen A, Jurik AG, van der Heijde D, Landewe R. Natural course of bone marrow oedema on magnetic resonance imaging of the sacroiliac joints in patients with early inflammatory back pain: a 2-year follow-up study. Scand J Rheumatol. 2015;44(2):129–34.CrossRefPubMed van Onna M, van Tubergen A, Jurik AG, van der Heijde D, Landewe R. Natural course of bone marrow oedema on magnetic resonance imaging of the sacroiliac joints in patients with early inflammatory back pain: a 2-year follow-up study. Scand J Rheumatol. 2015;44(2):129–34.CrossRefPubMed
15.
Zurück zum Zitat Lambert RG, Bakker PA, van der Heijde D, Weber U, Rudwaleit M, Hermann KG, et al. Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group. Ann Rheum Dis. 2016;75(11):1958–63.CrossRefPubMed Lambert RG, Bakker PA, van der Heijde D, Weber U, Rudwaleit M, Hermann KG, et al. Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group. Ann Rheum Dis. 2016;75(11):1958–63.CrossRefPubMed
16.
Zurück zum Zitat Mau W, Zeidler H, Mau R, Majewski A, Freyschmidt J, Stangel W, et al. Clinical features and prognosis of patients with possible ankylosing spondylitis Results of a 10-year followup. J Rheumatol. 1988;15(7):1109–14.PubMed Mau W, Zeidler H, Mau R, Majewski A, Freyschmidt J, Stangel W, et al. Clinical features and prognosis of patients with possible ankylosing spondylitis Results of a 10-year followup. J Rheumatol. 1988;15(7):1109–14.PubMed
17.
Zurück zum Zitat Tournadre A, Pereira B, Lhoste A, Dubost JJ, Ristori JM, Claudepierre P, et al. Differences between women and men with recent-onset axial spondyloarthritis: results from a prospective multicenter French cohort. Arthritis Care Res. 2013;65(9):1482–9.CrossRef Tournadre A, Pereira B, Lhoste A, Dubost JJ, Ristori JM, Claudepierre P, et al. Differences between women and men with recent-onset axial spondyloarthritis: results from a prospective multicenter French cohort. Arthritis Care Res. 2013;65(9):1482–9.CrossRef
18.
Zurück zum Zitat Ortolan A, van Lunteren M, Ramiro S, Ramonda R, Landewe RBM, Dagfinrud H, et al. Are gender-specific approaches needed in diagnosing early axial spondyloarthritis? Data from the SPondyloArthritis Caught Early cohort. Arthritis Res Ther. 2018;20(1):218.CrossRefPubMedPubMedCentral Ortolan A, van Lunteren M, Ramiro S, Ramonda R, Landewe RBM, Dagfinrud H, et al. Are gender-specific approaches needed in diagnosing early axial spondyloarthritis? Data from the SPondyloArthritis Caught Early cohort. Arthritis Res Ther. 2018;20(1):218.CrossRefPubMedPubMedCentral
Metadaten
Titel
The value of a repeat MRI examination of the sacroiliac joints following an inconclusive initial examination
verfasst von
Tamar Goitein Inbar
Merav Lidar
Iris Eshed
Publikationsdatum
09.01.2024
Verlag
Springer Berlin Heidelberg
Erschienen in
Skeletal Radiology / Ausgabe 6/2024
Print ISSN: 0364-2348
Elektronische ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-024-04561-2

Neu im Fachgebiet Radiologie

Ringen um den richtigen Umgang mit Zufallsbefunden

Wenn 2026 in Deutschland das Lungenkrebsscreening mittels Low-Dose-Computertomografie (LDCT) eingeführt wird, wird es auch viele Zufallsbefunde ans Licht bringen. Das birgt Chancen und Risiken.

Bald 5% der Krebserkrankungen durch CT verursacht

Die jährlich rund 93 Millionen CTs in den USA könnten künftig zu über 100.000 zusätzlichen Krebserkrankungen führen, geht aus einer Modellrechnung hervor. Damit würde eine von 20 Krebserkrankungen auf die ionisierende Strahlung bei CT-Untersuchungen zurückgehen.

Röntgen-Thorax oder LDCT fürs Lungenscreening nach HNSCC?

Personen, die an einem Plattenepithelkarzinom im Kopf-Hals-Bereich erkrankt sind, haben ein erhöhtes Risiko für Metastasen oder zweite Primärmalignome der Lunge. Eine Studie hat untersucht, wie die radiologische Überwachung aussehen sollte.

Statine: Was der G-BA-Beschluss für Praxen bedeutet

Nach dem G-BA-Beschluss zur erweiterten Verordnungsfähigkeit von Lipidsenkern rechnet die DEGAM mit 200 bis 300 neuen Dauerpatienten pro Praxis. Im Interview erläutert Präsidiumsmitglied Erika Baum, wie Hausärztinnen und Hausärzte am besten vorgehen.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.