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Indian Journal of Surgical Oncology
Erschienen in:

03.08.2020 | Review Article

The Value of Lymphadenectomy Post-Neoadjuvant Therapy in Carcinoma Esophagus: a Review

verfasst von: Syed Nusrath, Ajesh Raj Saxena, K. V. V. N. Raju, Sujith Patnaik, T. Subramanyeshwar Rao, Naren Bollineni

Erschienen in: Indian Journal of Surgical Oncology | Ausgabe 3/2020

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Abstract

Lymph nodal metastasis is one of the most important prognostic factors determining survival in patients with carcinoma esophagus. Radical esophagectomy, with the resection of surrounding lymph nodes, is considered the prime treatment of carcinoma esophagus. An extensive lymphadenectomy improves the accuracy of staging and betters locoregional control, but its effect on survival is still not apparent and carries the disadvantage of increased morbidity. The extent of lymphadenectomy during esophagectomy also remains debatable, with many studies revealing contradictory results, especially in the era of neoadjuvant therapy. The pattern of distribution and the number of nodal metastasis are modified by neoadjuvant therapy. The paper reviews the existing evidence to determine whether increased lymph node yield improves oncological outcomes in patients undergoing esophagectomy with particular attention to those patients receiving neoadjuvant therapy.
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Metadaten
Titel
The Value of Lymphadenectomy Post-Neoadjuvant Therapy in Carcinoma Esophagus: a Review
verfasst von
Syed Nusrath
Ajesh Raj Saxena
K. V. V. N. Raju
Sujith Patnaik
T. Subramanyeshwar Rao
Naren Bollineni
Publikationsdatum
03.08.2020
Verlag
Springer India
Erschienen in
Indian Journal of Surgical Oncology / Ausgabe 3/2020
Print ISSN: 0975-7651
Elektronische ISSN: 0976-6952
DOI
https://doi.org/10.1007/s13193-020-01156-w

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