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Erschienen in:

23.03.2021 | Original Scientific Report

The Worldwide Epidemiology of Acute Appendicitis: An Analysis of the Global Health Data Exchange Dataset

verfasst von: Dakshitha P. Wickramasinghe, Chrisjit Xavier, Dharmabandhu N. Samarasekera

Erschienen in: World Journal of Surgery | Ausgabe 7/2021

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Abstract

Background

This study aims to describe the worldwide epidemiology and changing disease trends of acute appendicitis (AA).

Methods

Epidemiological data on the incidence of AA and deaths were collected from the Global Health Data Exchange repository from 1990 to 2019. Data were stratified by age, sex and Socio-Demographic Index (SDI).

Results

In 2019, there were an estimated 17.7 million cases (incidence 228/100,000) with over 33,400 deaths (0.43/100,000). Both the absolute number and the incidence had increased from 1990 to 2019 (+ 38.8% and + 11.4%, respectively). The number of deaths and deaths per 100,000 declined during this period (− 21.8% and − 46.2%, respectively). These trends were largely similar in all 5 SDI groups. There was a significant difference in the incidence of AA between the SDI groups, with low SDI group having the lowest and high SDI group having the highest. The high SDI group had the lowest mortality rate (Kruskall–Wallis test, p < 0.001). The peak incidence was in the 15–19-year age group. The mortality rate increased exponentially from the third decade of life.

Conclusions

The mortality rate of AA is declining worldwide, while the incidence is increasing. The peak incidence is in the 15–19-year group.
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Literatur
2.
Zurück zum Zitat Bhangu A et al (2015) Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management. The Lancet 386(10000):1278–1287CrossRef Bhangu A et al (2015) Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management. The Lancet 386(10000):1278–1287CrossRef
3.
Zurück zum Zitat Buckius MT et al (2012) Changing Epidemiology of Acute Appendicitis in the United States: Study Period 1993–2008. J Surg Res 175(2):185–190CrossRef Buckius MT et al (2012) Changing Epidemiology of Acute Appendicitis in the United States: Study Period 1993–2008. J Surg Res 175(2):185–190CrossRef
4.
Zurück zum Zitat Ferris M, et al (2017) The Global Incidence of Appendicitis: A Systematic Review of Population-based Studies. Annals of Surgery 266(2) Ferris M, et al (2017) The Global Incidence of Appendicitis: A Systematic Review of Population-based Studies. Annals of Surgery 266(2)
5.
Zurück zum Zitat Davies Glenn M, Dasbach Erik J, Teutsch Steven (2004) The Burden of Appendicitis-Related Hospitalizations in the United States in 1997. Surgical Infections 5(2):160–165CrossRef Davies Glenn M, Dasbach Erik J, Teutsch Steven (2004) The Burden of Appendicitis-Related Hospitalizations in the United States in 1997. Surgical Infections 5(2):160–165CrossRef
6.
Zurück zum Zitat Evaluation., I.f.H.M.a., Global Health Data Exchange, I.f.H.M.a. Evaluation., Editor. 2020 Evaluation., I.f.H.M.a., Global Health Data Exchange, I.f.H.M.a. Evaluation., Editor. 2020
7.
Zurück zum Zitat Vos T et al (2020) Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the global burden of disease study 2019. The Lancet 396(10258):1204–1222CrossRef Vos T et al (2020) Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the global burden of disease study 2019. The Lancet 396(10258):1204–1222CrossRef
9.
Zurück zum Zitat Coward S et al (2016) Incidence of Appendicitis over Time: A Comparative Analysis of an Administrative Healthcare Database and a Pathology-Proven Appendicitis Registry. PLoS ONE 11(11):e0165161CrossRef Coward S et al (2016) Incidence of Appendicitis over Time: A Comparative Analysis of an Administrative Healthcare Database and a Pathology-Proven Appendicitis Registry. PLoS ONE 11(11):e0165161CrossRef
10.
Zurück zum Zitat Oguntola A, Adeoti M, Oyemolade T (2010) Appendicitis: Trends in incidence, age, sex, and seasonal variations in South-Western Nigeria. Ann Afr Med 9(4):213CrossRef Oguntola A, Adeoti M, Oyemolade T (2010) Appendicitis: Trends in incidence, age, sex, and seasonal variations in South-Western Nigeria. Ann Afr Med 9(4):213CrossRef
11.
Zurück zum Zitat Papadopoulos AA et al (2008) Dramatic decline of acute appendicitis in greece over 30 years: Index of Improvement of socioeconomic conditions or diagnostic aids? Dig Dis 26(1):80–84CrossRef Papadopoulos AA et al (2008) Dramatic decline of acute appendicitis in greece over 30 years: Index of Improvement of socioeconomic conditions or diagnostic aids? Dig Dis 26(1):80–84CrossRef
13.
Zurück zum Zitat Goldacre MJ et al (2011) Trends in mortality from appendicitis and from gallstone disease in English populations, 1979–2006: study of multiple-cause coding of deaths. Postgrad Med J 87(1026):245–250CrossRef Goldacre MJ et al (2011) Trends in mortality from appendicitis and from gallstone disease in English populations, 1979–2006: study of multiple-cause coding of deaths. Postgrad Med J 87(1026):245–250CrossRef
14.
Zurück zum Zitat Piri SM et al (2020) Trend of appendicitis mortality at national and provincial levels in iran from 1990 to 2015. Arch Iran Med 23(5):302–311CrossRef Piri SM et al (2020) Trend of appendicitis mortality at national and provincial levels in iran from 1990 to 2015. Arch Iran Med 23(5):302–311CrossRef
15.
17.
Zurück zum Zitat Bregendahl S et al (2013) Risk of complications and 30-day mortality after laparoscopic and open appendectomy in a Danish region, 1998–2007; a population-based study of 18,426 patients. Polish J Surg 7(85):395–400 Bregendahl S et al (2013) Risk of complications and 30-day mortality after laparoscopic and open appendectomy in a Danish region, 1998–2007; a population-based study of 18,426 patients. Polish J Surg 7(85):395–400
18.
Zurück zum Zitat Al-Omran M, Mamdani M, Mcleod RS (2003) Epidemiologic features of acute appendicitis in Ontario Canada Canadian journal of surgery. J Canadien de Chirurgie 46(4):263–268 Al-Omran M, Mamdani M, Mcleod RS (2003) Epidemiologic features of acute appendicitis in Ontario Canada Canadian journal of surgery. J Canadien de Chirurgie 46(4):263–268
21.
Zurück zum Zitat Andersson MN, Andersson RE (2011) Causes of short-term mortality after appendectomy: a population-based case-controlled study. Ann Surg 254(1):103–107CrossRef Andersson MN, Andersson RE (2011) Causes of short-term mortality after appendectomy: a population-based case-controlled study. Ann Surg 254(1):103–107CrossRef
Metadaten
Titel
The Worldwide Epidemiology of Acute Appendicitis: An Analysis of the Global Health Data Exchange Dataset
verfasst von
Dakshitha P. Wickramasinghe
Chrisjit Xavier
Dharmabandhu N. Samarasekera
Publikationsdatum
23.03.2021
Verlag
Springer International Publishing
Erschienen in
World Journal of Surgery / Ausgabe 7/2021
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-021-06077-5

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